Pre-pregnancy counselling - known medical problems Flashcards
What is Phenylketonuria?
inborn error of protein metabolism which causes an inability to metabolism essential amnio acid phenylalanine.
What is the effect of Phenylketonuria?
- when is it screened for?
high levels which causes mental developmental impairment.
- newborn babies- is amendable to treatment
What will a pregnant women with PKU have to do?
to restart her low phenylalanine diet to prevent high levels reaching the developing fetal brain.
most common thyroid disease in pregnancy?
- what medication will the female take?
hypothyroidism
Thyroxine
How does thyroxine demand change during pregnancy?
increased- doses may need to be increased
What is required for fetal brain development ?
normal thyroxine levels
A small number of women will be hyperthyroid entering pregnancy such as?
Graves disease - need treatment to keep hormone levels normal
What antibodies can cross the palcenta?
Thyroid stimulating antibodies - neonate needs to be checked
Women with type 2 diabetes need to be switched to?
insulin from oral hypoglyceamic meds
High blood glucose is associated with?
congential anomalies
Diabetic patients are more at risk of pregnancy complications such as ? (3)
Where should they be cared for?
pre-eclampsia, stillbirth and macrosomic infants.
joint diabetic obstetric antenatal clinic.
Renal patients are more likely to develop?
When might it be difficult to diagnose?
pre-eclampsia which may be difficult to diagnose if they already have proteinuria and pre-existing hypertension.
What does renal transplantation help to restore?
restores fertility as well as renal function.
main concern for women with epilepsy?
the effect of their anti-epileptic medication on their developing fetus.
What is an effective drug for women with epilepsy
Sodium valproate
