Practicals Flashcards
What is the usual expiry date of a diluted cream?
Freshly prepared
- 2 week expiry
What is the description of a ‘freshly prepared’ product?
It must be made no more than 48 hours before it is issued and given a 14 day expiry date.
What is the diluent directory?
A guide to which base can be used to dilute a cream/ointment
- Could also contact medicines information or the manufacturer
Which have a lower chance of microbial contamination and why? Creams or Ointments?
Ointments
- They have a lower water content than creams
What is the Expiry date of a cream manufactured extemporaneously from it’s raw ingredients?
4 weeks
What is the usual expiry date of a diluted ointment?
Freshly prepared
- 2 weeks
What is the Expiry date of an ointment manufactured extemporaneously from it’s raw ingredients?
3 months
What is the usual Expiry date of a solution?
4 weeks
Unless stated specifically otherwise or if it needs to be ‘freshly prepared’
What is the usual Expiry date of a suspension?
2 weeks
What are the important factors to consider when make solutions?
- Solubility of solute
- Stability of solute
- Chemical and Physical interactions
- What solvent to use
What is Solubility?
The maximum concentration to which a solution may be prepared with that agent in that solvent - at a given temperature
When is a solution saturated?
When a solvent, at a given temperature, has dissolved all of the solute it can
Most solutions for pharmaceutical use are NOT saturated
What are the requirements for containers for solutions?
- Child resistant caps
- Amber bottles
(- Fluted amber bottles for externals)
How should suspensions normally be stored?
In a cool dry place
What is a suspension?
a solid distributed in a liquid
The solid is insoluble
