Practicals Flashcards
1
Q
What is a monoclonal antibody?
A
2
Q
How do we produce monoclonal antibodies using murine derived spleen cells
A
3
Q
What is a hybridoma and how do we screen for their presence?
A
4
Q
In your practical sessions you tried to develop a mAb against CD20 – what is this molecule and why might it be a useful therapeutic target
A
5
Q
How is HAT media selective
A
6
Q
When might we use monoclonal antibodies
A
7
Q
What are the mechanisms of action of monoclonal antibodies?
A
8
Q
Why might we humanise monoclonal antibodies?
A
