Epitope Mapping Flashcards
1
Q
Can you define and compare linear versus conformational epitopes?
A
2
Q
What are the methods used to map epitopes?
A
3
Q
Why might you develop Mab approaches to diseases including ebola/sars COV2 viral infection ? Can you give examples? 1. Why is epitope mapping important?
A
4
Q
Can you define the following:
a. Linear epitope,
b. Confirmational epitope
c. Discontinuous epitope
A
5
Q
Describe three methods that could be used to map antigen-antibody interactions
A
6
Q
How does oligo-peptide scanning work?
A
7
Q
What are “CLIPS” and why are they sometimes used in epitope mapping?
A
8
Q
What is the therapeutic purpose of a neutralising mAb?
A
