Fragment Based Drug Delivery Flashcards

1
Q

What is fragment based screening?

A

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2
Q

What makes something a small molecule vs a fragment

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3
Q

What is the main goal of the fragment-based drug discovery approach

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4
Q

What strategies are used to improve fragment hits

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5
Q

What are the advantages of FBDD over high-throughput screening approaches

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6
Q

What makes a good fragment in drug discovery

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7
Q

How do DSF and SPR compare for screening of fragments

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8
Q

What are the rules of 3 and 5 – how do they compare ?

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9
Q

What are the applications of xray crystallography in fragment based discovery ?

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