Fragment Based Drug Delivery Flashcards
1
Q
What is fragment based screening?
A
2
Q
What makes something a small molecule vs a fragment
A
3
Q
What is the main goal of the fragment-based drug discovery approach
A
4
Q
What strategies are used to improve fragment hits
A
5
Q
What are the advantages of FBDD over high-throughput screening approaches
A
6
Q
What makes a good fragment in drug discovery
A
7
Q
How do DSF and SPR compare for screening of fragments
A
8
Q
What are the rules of 3 and 5 – how do they compare ?
A
9
Q
What are the applications of xray crystallography in fragment based discovery ?
A