Drug Delivery Flashcards
1
Q
What do we mean by tumour-associated hypoxia and what is the signalling pathway involved?
A
2
Q
Which factors in the tumour microenvironment can affect the uptake/effectiveness of drugs (and how)?
A
3
Q
What is a bioreductive drug and can you provide examples ?
A
4
Q
What is the function of carbonic anhydrases and which once are linked to cancer
A
5
Q
Differentiate between passive and active delivery of liposome -loaded drugs
A
6
Q
Define liposomes and how they can be generated from thin lipid film and MLV
A
7
Q
What is involved in the active and passive loading of liposomes with drugs?
A