PPT 4 Flashcards

1
Q

phenomenon in large
population when more than one wild type allele occur.

A

Genetic Polymorphism

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2
Q

altered pre-existing alleles cause by random mutation that occurs in the population.

A

Mutant Alleles

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3
Q

change the gene or the protein
encoded by a gene so that it gains a
new or abnormal function.

A

Gain-of-function mutations

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4
Q

change a protein such that the
mutant protein acts antagonistically
to the normal protein.

A

Dominant-negative mutations

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5
Q
  • dominant mutant allele is a loss of-function allele.
  • used to describe patterns of inheritance in which a
    heterozygote (with one functional allele and one inactive allele) exhibits an
    abnormal or disease phenotype
A

Haploinsufficiency

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6
Q

a situation
in which an allele that is expected to cause a particular
phenotype does not

A

incomplete penetrance

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7
Q
  • The hybrid (heterozygous)
    offspring displays a THIRD
    phenotype.
A

incomplete dominance

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8
Q

Neither trait is completely
dominant, as a result, there
appears to be a blending
phenotype.

A

incomplete dominance

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9
Q

condition in which the
phenotype of a heterozygote is
intermediate between the
corresponding homozygous
individuals

A

incomplete dominance

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10
Q

interaction between
genes that are alleles
and result in the
heterozygous
individuals being
superior to either of
the homozygous
parents.

A

overdominance

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11
Q

occurs when both alleles are expressed equally in the phenotype of the heterozygote.

A

codominance

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12
Q

may exist in a population level, and
different individuals in the population may have
different pairs of these alleles.

A

multiple alleles/multiple allelism

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13
Q

The gene for this trait is inherited through the X chromosome.

A

sex-influenced and sex-limited traits

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14
Q

If an allele makes one of these genes nonfunctional,
or causes it to take on an abnormal, harmful activity,
it may be impossible to get a living organism with a
homozygous genotype.

A

lethal genes

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15
Q
  • The multiple effects of a single gene on the phenotype of an organism is called
  • occurs when the expression of a
    single gene has two or more phenotypic effects
A

Pleiotropy

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16
Q
  • Phenomenon that describes how the allelic variants of two different
    genes affect a single trait.
  • can exhibit epistasis and complementation.
A

gene interaction

17
Q

the interaction between genes is
antagonistic, such that one gene masks or interferes
with the expression of another.

A

epistasis

18
Q

whenever a dominant allele conceals the expression of both
recessive and dominant alleles at other loci.

A

dominant epistasis

19
Q

when the
recessive allele conceals the expressing.

A

recessive epistasis

20
Q

when genes conceal other genes by suppression.

A

dominant inhibitory

21
Q

There is a recessive allele concealing the expression of dominant alleles at two loci

A

duplicate recessive

22
Q

there is a dominant allele concealing the expression of
recessive alleles at two loci.

A

duplicate dominant

23
Q

prevalent alleles in a natural population

A

Wild Type

24
Q

phenomenon in large
population when more than one wild type allele occur.

A

Genetic Polymorphism

25
Q

altered pre-existing alleles cause by random
mutation that occurs in the population

A

Mutant Alleles

26
Q

refers to the effects of environmental
variation on a phenotype

A

norm of reaction

27
Q

a phenotype in which two different parents that express the same or similar recessive phenotypes produce offspring with a wild-type phenotype.

A

complementation

28
Q

an allele of one gene modifies the phenotypic outcome f an allele of a different gene

A

modifying gene

29
Q

the loss of function in a single gene has no phenotypic effect, but the loss of function of two genes has an effect

A

gene redundancy