PP Psychiatry Flashcards
How is mejor depression diagnosed?
Need 5 " SIG E CAPS" >2 weeks - Sleep disturbances: wake in am - loss of Interest (anhedonia) - Guilt - Energy loss - Concentration loss - Appetite loss - Psychomotor agitation - Suicide: hopelessness Usually lasting 6-12 month
What is Autism?
Repetitive behavior
Lac of verbal skills and social interaction
Great focus on objects than on people
Below-normal intelligence
What is Asperger’s?
Milder form of autism Good communication Impaired relationships No mental retardation Normal intelligence
What is Rett’s?
Only in girls Regression Decrease head growth Lose motor skills Normal until 5month ( symptoms apparent around 1-4 y/o)
What is childhood disintegrative disorder?
Kids stop walking/ talking after 2 years of apparently normal development
Onset 3-4 years
More common in boys
What is the selective mutism?
Kids talk some time
What is Separation Anxiety Disorder?
Kids scream when Mom leaves
Common onset at 7-9 years
What is Conduct Disorder?
Before age 18 Aggressive Disregard for rule No sense of guilt Harm animals Illegal activity " bite"
What is Oppositional Defiant Disorder?
Defiant toward authority figures.
Noncompliant
What is Attention Deficit Heyperactivity Disorder?
Tx?
Onset before age 12
Normal intelligence
Overactivity
Difficulty in school
A/w decrease frontal lobe vol/ metabolism.
Tx : Methylphenidate, dextroamphethamine, atomoxetine
What is Dysthymia?
Milder form of depression lasting at least 2 years
What is cyclothymia?
Dysthymia w/ hypomania
Milder form of Bipolar disorder lasting at least 2 years
What is Bipolar I?
> 1 manic episode with or without Psychotic features
What is Bipolar II?
Hypomanic episode + MDD
What is Neologism?
New word
What is delusion?
False belief
What is illusion?
Misinterprets stimulus
What is Cataplexy?
Los of all muscle tone following strong emotional stimulus
* A/w Narcolepsy
What is paranoid personality disorder?
Suspicious about everything, use projection
What is Schizotypal personality disorder?
” Magical thinking”
Bizarre behavior
What is schizoid personality disorder?
“Recluse”
Don’t want to fit in
Distant
What is Antisocial personality disorder?
>18 year Lie Steal Cheat Destroy property Impulsive w/o remorse Illegally activity
What is Histrionic personality disorder?
Theatrical
Sexually provocative, Attention seeking, concern with appearance.
What is Borderline personality disorder?
Unstable mood and interpersonal relationships.
Self-mutilation, impulsivity , sense of emptiness
Splitting (love/hate) mechanisms of defense
What is Narcissistic personality disorder?
Grandiosity
No empathy
What is Dependant personality disorder?
Clingy
Submissive
Low self confidence
Regression
What is Obsessive-Compulsive personality disorder?
Perfectionist
Doesn’t show feeling
Detail-oriented
Uses isolation
What is Avoidant personality disorder?
Socially withdraw
Afraid of rejection but wants to fit in
What is Kleptomania?
Steal for the fun of it
What is Pyromania?
Starts fires
What is Trichotillomania?
Pull out their hair
What is Lewy body dementia?
Stiff, visual hallucinations
What is Normal Pressure Hydrocephalus?
TrIAD = Incontinence, Ataxia “ magnetic gait”, Dementia
What is Korsakoff psychosis?
Alcoholic Thiamine deficiency
What is vascular “ multi-infarct” dementia?
Sudden unset
Uneven progression of deficit
“ stair-step” decline
What is Huntington’s?
In caudate/putamen
Triplet repeat disorder
Choreiform movement
What is Creutzfeldt-Jacob?
Prion included
Die within 1 year
Post cornea transplant
What is Pick’s disease?
Frontal lobe atrophy
Disinhibition
What is Alzheimer’s ?
Decrease ACh in nucleus basales of Meynert
Bad ApoE
Amyloid plaques
Tangles bodies
What is Parkinson’s?
In substantial nigra Bradykinesia Pill-rolling tremor Shuffling gait Lewy bodies Decrease dopamine Increase serotonin and ACh
What is Somatization?
Think they have a different illness all the time (at least 4 organ system)
What is Hypochondriasis?
Think they have the same illness all the time
What is Body Dismorphic disorder?
Imagined physical defect
What is pain disorder?
Prolonged pain not explained by physical causes
What is Malingering?
*Secondary gain
Fake illness for monetary gain
Avoids medical treatment
What is Factitious?
*Sick role
Fake illness to get attention
Seeks medical treatment
What is Munchausen syndrome by proxy?
Need to be the caregiver
Mom fakes child’s illness to get attention
What is Amnesia?
Can’t recall important facts
What is Dossociative fugue?
Travel to new places with inability to recall the past
Usually due to trauma
What is Multiple Personality disorder?
Is a Dissociative identity disorder
Have 5-10 alters
Usually associated w/ incest
What is Depersonalization disorder?
“Out of body” experiences
Deja vu
What is Sublimation?
Replace an unacceptable wish with an action that is similar to the wish but doesn’t conflict with once values.
What is Displacement?
Transferring avoided feeling or ideas to a person or object.
What is Transference?
Patient views doctor as parent
* patient projects feeling onto physician
What is Acting out?
Unacceptable feelings and thoughts are expressed through actions
Ex: “Tantrums”
What is Regression?
- Immature behavior
- go back to previous stages
What is Rationalization?
“Justifying behavior to avoid difficult truth “
- logical reasons
- Make excuses for all situation to avoid self-blame
What is Intellectualization?
Act like a “know-it-all” to avoid feeling emotion
What is Isolation of Affect?
Is an immature defenses of the Ego
Isolate feeling to keep on functioning
What is Suppression?
Choosing to block memory
What is Repression?
Involuntarily block of memory
What is reaction formation?
Replace a bad idea or feeling by focusing on the opposite.
-Unconsciously act opposite to how you feel ( tears of a clown)
What is Sadism?
Gives pain
What is Masochism?
Receives pain
What is Exhibitionism?
Exposure to other
What is Voyeurism?
Watching other people without their permission
What is Frotteurism?
Rub penis against fully clothed women
What is Transsexual?
Gender identity crisis “ man trapped in a woman’s body”
What is Fetish?
Objects (vibrators, dildos, shoes)
What is Pedophile?
Children ( watching child pornography)
What is Necrophile?
Corpses
What is a Beastophile?
Animals
Can you die during EtOH withdrawal?
Yes
Can you die during Opiod withdrawal?
No; just very painful
What is Dissociation?
- drastic change in personality, memory, consciousness or motor behavior to avoid emotional stress
What is Denial?
- avoidance of awareness of some painful reality
What is Fixation?
- remaining at a more childish level of development
What is projection?
an unacceptable internal impulse is attributed to an external source
What is Splitting?
- belief that people are either all good or all bad
- commonly seen in Borderline personality disorder
What is Altruism?
- compensation
- alleviated the gilt with an unsolicited generosity toward others
Which are the childhood and early-onset disorder?
ADHD Conduct disorder Oppositional defiant disorder Tourette's syndrome Separation anxiety disorder
What is Tourette’s syndrome?
Onset before age 18 Tics that persist for > 1 year A/w OCD and ADHD Treatment: - fluphenazine - pimozide - tetrabenazine - clonidine - haloperidol
Types of amnesias?
- Retrograde: before the event
- Anterograde: after the event ( new memory)
- Korsakoff’s : anterograde, caused by thiamine defi., destruction of mammillary bodies, associated with confabulation
- Dissociative: inhability to recall personal information after trauma or stress
What is a Psychotic disorder?
Distorted perception of reality
Characterized bay delusion, hallucination and/or disorganized thinking
Which are the sings of psychosis?
Hallucinations
Delusions
Disorganized speech
What is Schizophrenia?
Mental disorder with periods of psychosis Impaired functioning Symptom last > 6 month Increase dopamine Have positive and negative symptoms
Brief psychotic disorder ?
< 1 month, stress related
What is Schizophreniform disorder ?
Same as schizophrenia but the time is different 1-6 month
What is Schizoaffective disorder?
Needs to present at least 2 weeks of psychotic symptoms with a stable mood and an episode of major depression, manic or mixed
What is a Delusional disorder?
Fixed, persitent, nonbizarre belief system lasting > 1 month
Functioning is not impaired
What is an Hypomanic episode?
Like a Manic episode, except mood disturbance is not severe enough to cause impairment
What is Atypical depression?
Subtype of depression that is characterized by:
- Hyperphagia
- Hypersomnia
- Mood reactivity
- Rejection hypersensitivity
What is Post-traumatic stress disorder?
Disturbance last > 1 month
My involve nightmares or flashback
What is Acute-stress disorder?
Disturbance present between 2 days and 1 month
What is Generalized anxiety disorder?
Pattern of uncontrollable anxiety for at least 6 month
What is Conversion?
Sudden loss of sensory or motor Function, following an acute stressor
Time corse of schizophrenia?
< 1 month : brief psychotic disorder
1-6 month: Schizophreniform
> 6 month : schizophrenia
What is anorexia nervosa?
Excessive dieting Intense fear of gainin weight Body image distortion Amenorrhea Increase exercise
What is Bulimia nervosa?
Binge eating
Self induce vomiting or use of laxatives, diuretics or emetics
Associated with: parotitis, enamel erosion, electrolyte disturbance, alkalosis
Treated with: Fluoxetine
Which are the Depressants drugs?
- Alcohol
- Opioids ( morphine, heroine, methadone)
- Barbiturates
- Benzodiazepines
Which are the Stimulants drugs?
Amphetamines
Cocaine
Caffeine
Nicotine
Which are the Hallucinogens drugs?
PCP
LSD
Marijuana
How are classify the Antipsychotics?
Typical ( traditional neuroleptics) - low potency - high potency * block Dopamine D2 receptor { increase cAMP} Atypicals
Which are the low potency Antipsychotics?
Chlorpromazine
Thioridazine
Which are the High potency Antipsychotics?
Haloperidol Fluphenazine Loxapine Thiothixene Trifluoperazine
Which are the Atypicals Antipsychotics?
Olanzapine Quetiapine Risperidona Aripiprazole Clozapine ( causes agranulositosis)
Buspirone?
Stimulates 5-HT1A receptors
Use for Generalized anxiety disorder
Which are the types of Antidepresants?
SSRIs: inhibits re-uptake of Serotonin
SNRIs: inhibits re-uptake of Norepinephrine and Serotonin
TCA: inhibits re-uptake of Norepinephrine and Serotonin
MAOI: inhibits enzyme that metabolize and inactivates Norepinephrine
Which are the SSRIs?
Fluoxetine
Paroxetine
Sertraline
Citalopram
Which are the SNRIs?
Venlafaxine
Duloxetine
Which are the TCA?
Amitriptyline Nortriptyline Imipramine Desipramine Clomipramine Doxepin Amoxapine
Which are the MAO?
Tranycypromine
Phenelzine
Isocarboxazid
Selegiline
Which are the Atypical Antidepressants?
Buspiron
Mirtazapine:
Maprotiline:
Trazodone:
Lithium is use for?
Mood stabilizer for Bipolar disorder
Blocks relapse and acute manic event
What is akathisia?
restlessness
inability to sit still
Which are the diagnostic criteria for a Manic episode?
"DIG FAST" Disutractibility Irresponsibility Grandiosity Flight of ideas Increase Activity/ Agitation Sleep Talkativeness
What is a Manic episode?
Period of abnormally and persistently elevated, expansive or irritable mood
Lasting at least 1 week
Generalized anxiety disorder?
Chronic multiple worries, anxiety, tension.
Mention the Key clinical features for acute drug intoxication?
- PCP
- LSD
- Cocaine
- Methanphetamine
- Marijuana (Canabis)
- Heroine
- Nystagmus, violent behavior
- Visual hallucinations
- CP, seizures, Mydriadis ( dilated pupil )
- Choreiform movement, tooth decay
- Conjunctival injection ( red eyes), increase appetite
- Depressed mental status, Miosis ( constricted pupil), respiratory depression
What is adjustment disorder?
Involves emotional or behavioral symptoms developing within 3 months of an indentifiable stressor.
Which are the 2 types of Breath-holding spell?
- They are benign
- Characterized by brief period of apnea and skin color change
- Common in children age 6mo - 2y
1. Cyanotic type:
-crying & BH follow by apnea and loss of consciousness.
-brief with rapid return to baseline.
2. Pallid type:
-trigger by minor trauma
-fleeting loss of consciousness follow by BH, pallor & diaforesis
-less than 1 min with subsequent confusion and sleepiness for a
few min
Nightmare disorder vs. Sleep terror disorder?
- Nightmare: recurrent awakening from REM sleep, full alertness, dream recall, can be consoled.
- Terror: non-REM arousal, incomplete awakening, cannot recall dream, unresponsiveness to confort
Delayed vs. Advanced sleep phase syndrome?
*circadian rhythm disorder characterized by the inability of:
- Delayed: fall asleep at normal bedtime ( results in sleep-onset insomnia & daytime sleepiness)
- Advanced:stay awake in the evening, past 7 ( result in social functioning & early morning insomnia)
Catatonia
A syndrome seen in severe psychiatric &a medical illness.
- Characterized by: immobility, mutism and posturing.
- A Lorazepam challenge test can confirm the Dx
- Tx: Benzodiazepine, ECT for pt that don’t improve.
Dissociative identity disorder
Discontinuity in identity and loss of personal agency with fragmentation into >2 distinct personality state
New onset of severe GI symptoms, confusion, ataxia and tremors.
Lithium toxicity
- use of Lithium in combination of : Thiazides, ACE-inhibitors, Tetracyclines, Metronidazole
Prevalent comorbid conditions that complicate the management and quality of life in pt with Tourette sy.
ADHD
OCD
Neuroleptic Malignant syndrome signs/symptoms?
Muscle rigidity Fever > 40C (104F) Confusion Autonomic instability Increased CK Leukocytosis
*Serotonin syn: tremor, hyperreflexia, myoclonus, Fever but not as high, nausea and vomiting.
Dissociative Amnesia
Inability to recal important personal info; usually of a traumatic or stressful nature
- Not exploded by another disorder
Precontemplation?
Not yet acknowledged that there is a problem
Atypical depression is characterized by?
Mood reactivity ( feeling better in response to positive events) Laden paralysis (extremities feel heavy) Rejection sensitivity ( overly sensitive to criticism) Increase sleep and appetite
Acute stress disorder Vs. Post-traumatic stress disorder
ASD: more than 3days but less than a month
PTSD: persistence of symptoms for more than a month
4hour Acute dystonia Tx?
Anticholinergics:
- Benztropine
- Diphenhydramine
- symptoms: muscles spasm, stiffness, oculogyric crisis
4 month Tardive dyskinesia?
Involuntary movement ( tongue,lips, face, extremities) * Clozapine may help
Serotonin syndrome is characterized by a triad of?
- Autonomic instability: hyperthermia, HTN, tachycardia
- AMS
- Neuromuscular hyperactivity ( hyperreflexia, miotonic)
Action/ willpower
Changing behavior
Pt experiencing MDD episode should be screen for?
Past MANIC episode to rule out Bipolar disorder
Contemplation
Acknowledging that there is a problem, but not yet ready or willing to make a change
Depressant drugs?
Alcohol
Opioids (morphine, heroin, methadone)
Barbiturates
Benzodiazepines
Delusions or hallucinations fro more than 2 weeks in the absence of MD episode or manic episode is?
Schizoaffective disorder
Symptoms of opioids intoxication?
- morphine, heroin, methadone
Euphoria
Respi & CNS depression
Pupillary constriction ( point pupil)
-Tx for overdose: Naloxone
Caine withdrawal is characterized by?
Acute depression accompanied by:
- Vivid dreams
- Hyperinsomnia
- Hyperphagia
- Fatigue
Dilate pupils, yawning, lacrimation
Heroin withdrawal
- in baby - look for sneezing, vomiting, diarrhea
Pupillary findings on intoxication with
- Stimulants
- Depressants
- Stimulants- dilate
2. Depressant- constrict
Delirium is characterized by?
Acute
Fluctuating cognitive impairments
Ex. Poor attention, disorientation
Alcohol withdrawal syndrome 6-24hrs?
Mild
-symp: anxiety, insomnia, Tremors, diaphoresis, palpitations, GI upset, oriented.
Alcohol withdrawal syndrome 12-48hrs?
- seizures
- hallucinations
- oriented
- normal VS
Alcohol withdrawal syndrome 48-96hrs?
Delirium tremors
- confusion, agitation, fever, tachycardia, HTN, diaphoresis, hallucinations
Tx for Neuroleptic malignant syndrome?
- Dopaminergic agents: Bromocriptine, Amantadine
- Muscle relaxant: Dantrolene
Most consistently replicated neuroimaging finding in schizophrenia?
Enlargement of the. Lateral cerebral ventricles
Specific phobia?
Excessive anxiety about specific object or situation.
Panic disorder?
Recurrent, unexpected panic attack’s
Neurotransmitter changes in Alzheimer disease?
Decrease ACh
Increase glutamate
Neurotransmitter changes in Anxiety?
Increase NE
Decrease GABA and 5-HT
Neurotransmitter changes in Depression?
Decrease: NE, dopamine and 5-HT
Neurotransmitter changes in Huntington disease?
Increase:dopamine
Decrease: GABA and ACh
Neurotransmitter changes in Parkinson disease?
Decrease dopamine
Increase ACh
Sensation of bugs crawling
MC in alcohol withdrawals
Also seen in cocaine abusers
Negative symptoms of schizophrenia?
Flat affects
Social withdrawals
Lack of motivation
Lack of speech or thought .
-Symptoms improve with antipsychotic
Maternal blues
Starts 2-3 days after delivery
Symptoms: depress affect, tearfulness and fatigue.
Tx supportive, FU for evaluation of PD
Postpartum depression (PD)
Starts after 4 weeks of delivery
Symptoms: depression, anxiety, poor concentration
Tx CTB AND SSRI 1 line
Common side effect of ECT?
Amnesias: retrograde and anterograde
Social anxiety disorder?
Social phobia
- anxiety restricted to social & performance situations.
- fear of scrutiny & embarrassment.