PP Micro Flashcards
What makes an adequate sputum sample?
< 10 epithelial cells and > 25 leukocytes per low power field
How do you know it’s an anaerobe?
Gas
Bad odor
What bugs causes acute bacterial endocarditis?
Staph aureus ( attacks healthy valves)
What bug causes subacute bacterial endocarditis?
Strep viridians ( attack damage valves)
How do you diagnose Rheumatic fever?
Need at least 2 “SPECC”
- subcutaneous nodules
- Polyarthritis
- erythema marginatum ( red margins)
- chorea (Sydenham’s)
- carditis ( MS > AS > TS )
What are the only Gram - diplococci?
Neisseria
What is the only Gram + diplococci?
Strep pneumo
What bugs cause heart block infection?
“Don’t TeLL Chaga”
- diphtheria
- typhoid fever ( salmonella typhii)
- legionella
- Lyme disease
- Chaga’s disease
What are the IgA protease bugs?
Strep pneumo
H. Influenza
Neisseria Catt.
What do the IgA protease bugs cause?
Sinusitis
otitis media
Pneumonia
Bronchitis
What are the simple Gram - bugs?
” simple HE “
- H. Influenza
- E. Coli
What are the atypical ( no cell wall) bacteria?
“CLUMsy”
- chlamydia
- legionella
- ureaplasma
- mycoplasma
What is the only Gram + endotoxin?
Listeria
What is the only Gram - exotoxin?
H. Influenza
Bordetella pertussis
What are the spore forming Gram + bacteria?
Bacillus anthracis
Clostridium botulinum
What bugs cause walking pneumonia?
“Come My Love for a walk”
- 0-2mo: Chlamydia pn.
- 10-30 y: Mycoplasma pn.
- > 40 y: Legionella pn.
- AIDS/Premies: Pneumo Jirovecii
What causes Cryolgobulinemia?
“I AM HE”
- influenza
- adenovirus
- mycoplasma
- hep. B, C
- EBV
What are the Silver Stainers?
” HaLV-C = Comma”
- H. Pylori
- Listeria
- Vibro
- Campylobacter
What bacteria cause diarrhea < 8h after introduction?
“CBS”
- Clostridium
- Bacillus cereus
- Staph aureus
What are the Gram - capsule?
“Some Killers Have Pretty Nice Capsule”
- salmonella
- klebsiella
- H. Influenza B
- pseudomonas
- neisseria
- citobacter
What is the Gram + capsule?
Strep pneumo
What are the Urease + bugs?
“Urease PPUNCH”
- proteus
- pseudomonas
- ureoplasma
- nocardia
- cryptococcus
- H. Pylori
What bugs cause Monocytosis?
” STELS”
- syphilis
- TB
- EBV
- Listeria
- Salmonela
What are the Big Mama Anaerobes?
Bacteroides fragilis
Strep. Bovis
C. Septicum
What bugs disrupt G protein?
Perturris: inhibits Gi
Cholera: stimulates Gs
E. Coli: stimulates Gs
What bug is associated w/ cat scratch?
Bortonella henselae
What bug is associated w/ cat saliva?
Pasturella multocida
What bug is associated w/ cat pee?
Toxoplasmosis
What bug is associated w/ cat caca?
Toxic area cati
What disease are cause by the Ixodes Tick?
Lyme disease - bull’s eye lesion
Babesiosis - hemolytic anemia
Ehrlichiosis - puncture near eye
What bugs cause hospital abscesses?
Day 1-3: Staph aureus -> lost of O2
Day 4-7: Step viridians -> no enzyme
Day >7: Anaerobe -> PMNs
What kind of patients does Staph and Pseudomonas like to attack?
DM
Cystic fibrosis pts
Burn pts
Neutropenia pts
What disease have granulomas?
TB Sarcoidosis Syphilis Histocytosis X The ella's
What disease provide malaria protection?
Sickle cell : AAs
G-6PD: Mediterranean
What bug causes multiple liver abscesses?
Entamoeba histolytica
What bug causes multiple cerebral abscesses?
Citrobacter
What has multiple lung aneurysm?
Osler-Weber-Rendu
What bugs cause Loesffler syndrome?
“NASSA”
- necator americanus
- ancylostoma duodenal
- schistosomiasis
- strongyloides
- ascaris lumbricoides
What is the symptom of Loeffler syndrome?
Pulmonary eosinophilia
What is PIE syndrome?
Pulmonary infiltrate w/ Eosinophilia
What disease have PIE syndrome?
Aspergillus
Loeffler
Churg-Strauss
What disease does Coxsackie A cause?
Hand-Foot-Mooth disease
What disease does Coxsackie B cause?
Endocarditis
DM type 1
What bugs cause Meningitis?
0-2mo: "baby BEL" - group B strep - E. Coli - Listeria > 2mo: strep pneumo 10-21y/o: N. Meningitidis
What are the CSF lbs values for Meningitis?
PMNs-> bacteria
T cells/ MP -> non-bacterial
Normal glucose - > viral
What does the Hep B Core AG tell you?
Gone before pt has symptoms ( 2 mo)
What does the Core Ab tell you?
Past infection
What does the Surface Ag tell you?
Current infection
What does the Surface Ab tell you?
Vaccination has occurred
What does the E Ag tell you?
Transmissibility / infectivity
What does the E Ab tell you?
Low transmissibility
What antibody show current Hep A infection?
IgM
Urease + Bacteria?
"PPUNCHES" Proteus Pseudomonas Ureaplasma Nocardia Cryptococcus neoformans H. Pylori S. Saprofiticus
What antibody shows past Hep A infection?
IgG
What type of people does Hep E like to infect?
Pregnant women
Asians
What is associated w/Staph aureus?
Cellulitis Dairy products Gold pigment Endocarditis Styles Hordeolum (on eyelid)
What is associated w/ Strep pyogenes?
“LINES”
ASO
Hyaluronic acid capsule
What is associated w/ Staph epidermidis?
Central lines
VP shunt
White pigment
What is associated w/ Propionibacterium?
Acne
Progesterone => prop ionic acid
What is associated w/ Pasteurella Multicoda?
Cat/ dog saliva => cellulitis w/ lymphadenitis
What is associated with Staph saprophyticus?
Female UTIs, honeymooners cystitis
What is associated w/ Hemophilus aegyptus?
Swollen eyeball w/ pus
What is associated w/ Francisella tularensis?
Ulcers at rabbit or deer tick bite site
What is associated w/ Pseudomonas aeruginosa ?
Otitis external Ecthyma granulosum Loves rubber Whirlpool folliculitis ADP ribosylates EF-2
What is associated w/ Streptococcus pneumoniae?
Otitis media
Red bulging tympanic membrane
What is associated w/ Fusobacterium?
Painful mouth ulcers
Gum pus
Vincent’s angina
What is associated w/ Strep mutans?
Dental cavities
What is associated w/ Strep viridians?
Subacute bacterial endocarditis
Green pigment
What is associated w/ Strep salivarius?
Cold agglutinin test
What is associated w/ Strep pyogenes?
Rheumatic fever, strain 12 => PSGN
What is associated w/ Group C strep?
Pharyngitis
What is associated w/ Corynebacterium?
Chinese letters Gray pseudomembrane Suffocation ADP ribosylates EF2 Heart block Leek test
What is associated w/ Strep pneumonia?
Gram + diplococci
Rusty sputum
IgA protease
Vaccine covers 23 strains
What is associated w/ H. Influenza?
Gram - pleomorphic rod
Factor V/X
5C-ribose capsule
B-type: meningitis, Epiglotitis, sepsis
What is associated w/ N. Catarrhalis?
Loves mucus -> attacks respiratory tract
What is associated w/ Chlamydia psittaci?
Parakeets, parrots
What is associated w/ Chlamydia pneumonia?
Staccato coughing
Elementary and reticulate bodies
What is associated w/ Mycoplasma?
Bullous miringitis
Ground-glass CXR
P1 protein
Erythema multiforme
What is associated w/ Legionella pneumonia?
AC ducts Silver stain lung CYEA Pontiac fever Legionnaire pneumonia
What is associated w/ Pneumocystis Jiroveciinia?
AIDS/ Premies
Rusty sputum
Silver stains lung
Increase LDH
What is associated w/ Clostridium botulinum?
Canned food Honey Inhibits ACh release Resp. Failure Stool toxins
What is associated w/ Clostridium tetani?
Rusty nail wounds Inhibits Gly release Resp. Failure Risus sardonicus Tennis racquet shape
What is associated w/ Bordetella pertussis?
Whooping cough
ADP ribosylates Gi
What is associated w/ Bacillus anthracis?
Black eschar
Woolsorter’s lung disease
D-Glu
Boxcar-like spore
What is associated w/ H. Pylori?
Duodenal ulcer
What is associated w/ Slamonella?
Raw chicken & eggs Turtles Rose typhoid spots H2S Sickle cell osteomyelitis
What is associated w/ Campylobacter jejuni?
Raw chicken & eggs Very bloody diarrhea Inactivated bay gastric juice Guillain-Barre Seagull-shape
What is associated w/ clostridium perfringens?
Holiday ham & turkey
DM gas gangrene
Soil/ feces
What is associated w/ Bacillus cereus?
Fried rice
Pre-formed toxin
What is associated w/ Listeria Monocytogenes?
Raw cabbage Hot dog Spoiled milk Migrant workers=> heart block Meningitis Abortions
What is associated w/ Vibrio parahaemolyticus?
Raw fish
What is associated w/ actinomyces?
Face fistulas
Sulfur granules
What is associated w/ Vibrio vulnificus?
Raw oysters
Cellulitis in swimmer’s cuts
What is associated w/ Shiguella?
Day care outbreaks
Seizures
Destroys 60S ribosome
Infects M cells
What is associated w/ Vibrio cholera?
Rice water diarrhea
ADP rybosilates Gs
What is associated w/ Clostridium difficile?
Explosive diarrhea = Pseudomembranous colitis
What is associated w/ Yersinia enterocolitica?
Presents like Apendicitis + Reiter’s
Bloody diarrhea
What is associated w/ Strep bovis?
Colon cancer
Black pigment
What is associated w/ Clostridium seticum?
Colon cancer
What is associated w/ ETEC?
Traveler’s => rice-water diarrhea
What is associated w/ EHETC?
Hemorrhagic => renal failure
What is associated w/ EIEC?
Inflammatory => loose stool
What is associated w/ EPEC?
Pathogenic => newborn diarrhea
What is associated w/ E. Coli?
Raw hamburger
ADP rybosilates Gs
Verotoxin
HUS
What is associated w/ Proteus mirabilis?
Staghorn calculus
UTI
What is associated w/ Klebsiella pneumonia?
Alcoholic
Currant jelly sputum
UTI
Lung fissures
What is associated w/ Staph saprophyticus?
Young and collage girls UTIs
What is associated w/ Enterococcus?
UTI
Infective endocarditis post GI/ GU procedure
What is associated w/ N. Meningitidis?
DIC
Pili
Release toxin in log phase
What is associated w/ Brucella?
Farmers/ vet
Spiking fever 5x/day
Animal placenta
What is associated w/ R. Rikettsii?
Ticks => Rocky Mountain spotted fever
What is associated w/ R. Akari?
Mites => flesh papules
What is associated w/ R. Typhi?
Fleas
Starts in armpit
What is associated w/ R. Prowazekii?
Lice
Starts on body
What is associated w/ R. Tssutsugamushi?
Mites => scrub typhus
What is associated w/ Coxiella busrnetii?
Dusty barn => Q fever
What is associated w/ Yersenia pestis?
Rats
Fleas
Bubonic plague
What is associated w/Bartonella henselae?
Cat scratch => single painful lymph node
Silver stain
What is associated w/ Bacteroides fragilis?
Post-op bowel abscess
Grows in blood clots
What is associated w/ Chlamydia trachomatis?
Neonatal inturned eyelashes/ cornea ulcers
What is associated w/ N. Gonorrhea?
Pili
Urethritis
Tenovitis
Septic arthritis
Enterobacteriaceae?
(E. Coli, Salmonela, Shigella, Klebsiella, Enterobacter, Serratia Proteus)
- Gram (-)
- All have somatic (O) antigen
- Capsular (K) antigen
- Flagelar (H) antigen
- All ferment glucose
- All are oxidative (-)
What bugs cause Food poisoning?
Vibrio Parahaemolyticus & V. Vulnificus ( contaminated seafood)
Bacillus Cereus ( reheated rice)
S. Aureus (meats, mayonnaise and custard)
Clostridium Perfringens ( reheated meat)
C. Botulinum ( canned food)
E. Coli O157:H7 ( undercooked meat)
Salmonella ( poultry, meat and eggs)