PowerPoint 2 Flashcards
What is a gold standard test?
Test with highest accuracy
Sensitivity of a test?
How often test shows abnormality in population with disease accurately.
Specificity of a test?
How often test does not show abnormality in population without disease
Four-step process in diagnosing heart disease?
-Initial medical history and physical exam
-Align with recommendations of the American College of Cardiology(ACC) and the American Heart Association (AHA)
-Assess patient with noninvasive and invasive tests
-Diagnosis is highly evidence based, providing sufficient information while containing costs
AHA decision tree eight steps?
-Contraindication to Stress testing?
No
-Symptoms or clinical findings warranting Angiography?
No
-Pt. able to Exercise
Yes
-Previous Coronary revascularization
No
-Resting ECG interpretable?
Yes
-Perform Exercise test
Choose test appropriately
-Test results suggest high risk?
No –> diagnosis Yes –> angiography
-Adequate info on DX and Prognosis available?
Yes
When is an exercise test performed as an initial diagnostic tool?
Patient has chest pain, can exercise, and normal resting ECG
What six things are looked for in an exercise test?
CAD
Fitness level
Pathology of dyspnea
What does exercise do to your body?
Return to work test
Gives insight on severity of disease(s)
How safe are exercise tests?
-Generally safe, if prescreening is done properly
-1/2500 tests experience MI or Death
What is the most popular types of exercise test protocol?
Bruce or modified bruce
Exercise tests should not be longer than ____-____ minutes?
12-14
What is an echocardiogram?
Visual inspection of the anatomy
Ability to capture images in various stages of cardiac cycle
What does an exercising echo do?
Compares images at rest and immediately post-exercise
Normal response to exercise-exercise echo?
Augmentation of the left ventricular wall.
Increased ejection fraction and left ventricular size.
Ischemic heart response to exercise-exercise echo?
Normal LV wall motion at rest.
Hypokinesis of LV wall when >70% artery stenosis
MI pts show no changes in ____ ____ wall at ____ or with ____?
MI pts show no changes in LV wall at rest or with exercise
Echo’s improve confidence level for Ischemia in heart from ~ ____ (standard exercise stress test) to ____-____%.
Echo’s improve confidence level for Ischemia in heart from ~ 75% (standard exercise stress test) to 80–85%.
Appropriate candidates for echocardiography?
-Intermediate pretest probability of coronary artery disease and uninterpretable rest ECG.
-Previous revascularization.
Who has a high probability of false-positive exercise test?
Women and patients with concurrent valvular or primary myocardial disease.
Inappropriate candidates for exercise echocardiography?
Multiple myocardial infarctions
Complex wall motion abnormalities
Obese and COPD
Inadequate ambulation (pharmacologic test possible alternative)
When to use pharmacologic echocardiography?
When exercise is contraindicated
What drug is used in pharmacologic echocardiography?
Dobutamine
What is myocardial perfusion imaging?
When radioisotopes are injected near peak exercise.
-Compare myocardial uptake immediately post exercise versus rest.
When is myocardial perfusion imaging indicated?
Follow-up to abnormal resting ECG.
Patients taking digitalis.
Women.
Angiographic-documented CAD.
When is myocardial perfusion imaging selected?
Uninterpretable resting ECG
Unable to reach high HR or SBP during exercise
Moderate/high risk symptoms in Pt
History of bypass surgery
Referred for echo but poor echo images
When is myocardial perfusion imaging contraindicated?
Risk with exercise
Hx of Bronchospasm with vasodilation drugs.
What is the gold standard for assessing CAD?
Coronary angiography
What is coronary angiography?
Cardiac catheterization (gold standard)
Dye injected to highlight arteries during X-ray
Displays limited flow at lumen stenosis or blockages
How is ischemia determined in coronary angiography?
-Coronary artery lumen restriction (lesion) > 70% = ischemia.
-Lesions between 50% and 70% of lumen diameter = borderline.
-Lesions < 50% stenosed; not generally thought to cause ischemia.
What might intravascular ultrasound be beneficial in?
-Identify lesions requiring revascularization.
-Evaluate vessel patency and stent operation.
-Determine amount of obstruction from individual plaque, when Doppler is used in conjunction with IVUS.
What is PCI?
Percutaneous coronary intervetions
What are two PCI?
AKA coronary angioplasty
Noninvasive surgical procedure using balloon to reestablish normal blood flow in affected coronary arteries.
High (25–50%) rate of restenosis within the initial 6 months without stent.
Drug eluting stent (DES) restenosis rate ~23%.
What is CABG?
Coronary artery bypass graft surgery