Post transcriptional control Flashcards by Lina Salazar-Bejarano | Brainscape

Q

How is mRNA processed?

A

Transcription, 5’ capping
Cleavage at Poly A site
Addition of Poly A tail
RNA splicing

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Q

How is mRNA modified?

A

mRNA is made 5’ to 3’ so phosphorylation of 5’ is forward

P removed and base pairs methylated

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Q

Describe the process of 5’ cap

A

mRNA is made 5’ to 3’ so phosphorylation of 5’ is forward

P removed and base pairs methylated

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Q

Describe the process of Poly A adding

A

At C Terminus of RNA pol, proteins on end of tail leave and cleave at AAUAAA and then recruits Poly A POL which extends tail.

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Q

How are snRNPs sliced?

A

Happens in a 2 step transesterification. Exposed OH attaches to same intron loop causing it to break off.

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