Population Genetics

Question 1

Why do you have to supplement PKU patient with tyrosine in addition to avoid aspartame and phenylalanine?

Answer 1

.

Question 2

Why can we estimate genotype frequencies if one knows allele frequencies and vice versa based on hardy-Weinberg equilibrium?

Answer 2

Because there is a constant and predictable relationship between genotype frequencies and allele frequencies (Hardy-Weinberg equilibrium)

Question 3

What factors can deviate the the hardy-Weinberg equilibrium?

Answer 3

• New mutations (founder effect)
• nonrandom mating (consanguinity)
• Natural selection
• Genetic drift
• Genetic flow

Question 4

How is the risk of a genetic disease to the offspring of a first-cousins mating?

Answer 4

Risk is twice as likely respect offspring of unrelated matings

Question 5

How much genetic information does first cousins share?

Answer 5

Approximately 1/8 of their genes

Question 6

How much genetic information does second cousins share?

Answer 6

Approximately 1/32

Question 7

How much genetic information does half-cousin share?

Answer 7

Approximately 1/16