Nucleic Acid Structure And Organization

Question 1

What is the most likely source of nucleic acid that doesn’t match chargaff’s rules, type of nucleic acid?

Answer 1

Viral genome (ssDNA)

Question 2

Mention 4 differences between gene expression and replication

Answer 2

• Replication: DNA copy, long sequence (entire chromosome), S phase, nucleus
• Expression: RNA copy, short sequence (small section of chromosome), Interphase, cytoplasm

Question 3

What antitumor drugs intercalate between the bases of DNA interfering with topoisomerase II preventing correct replication? What disease treat?

Answer 3

Daunorubicin and Doxorubicin (leukemia treatment)