Population Genetics Flashcards

1
Q

Define population genetics.

A

Population genetics is the quantative study of the distribution of genetic variation in populations and how the frequencies of genes and genotypes are maintained or changed.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the four main evolutionary forces that affect allele frequency?

A
  1. Natural Selection 2. Genetic Drift 3. Mutation 4. Gene flow
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

__________ is the mechanism for a genome mutation.

A

Chromosome missegragation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

__________ is the mechanism for a chromosome mutation.

A

Chromosome rearrangement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

____________ is the mechanism for a gene mutation

A

Base Pair mutation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How many genes does each individual have?

A

25,000

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Each new baby has a _______ risk of a new mutation at one locus.

A

2.6%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is incidence equal to?

A

Incidence is twice the mutation rate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the idealized assumptions in the Hardy-Weinber Equilibrium?

A
  1. Large population mating randomly 2. allele frequencies remain constant over time because no new mutation, no natural selection and no immigration/emigration
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is stratification?

A

Refers to a population containing two or more subgroups which tend to preferentially mate with their own subgroup

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is assortive mating?

A

Refers to when the choice of mat is dependent on a particular trait

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the three factors that contradict random mating?

A
  1. Stratification 2. Assortive mating 3. Consanguinity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

__________ affect the number of chromosomes in the cell.

A

Genome mutations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

_____________ alter the structure of individual chromosomes.

A

Chromosome Mutations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

____________ can alter individual genes.

A

Gene mutations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

In Huntington’s disease, the error comes from the _________

A

Father

17
Q

In fragile X syndrome, the error comes from the __________

A

Mother

18
Q

In x-linked disease, there are ________ possible male genotypes and ________ possible female genotypes.

A

Two; three