Population Genetics Flashcards

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1
Q

Define population genetics.

A

Population genetics is the quantative study of the distribution of genetic variation in populations and how the frequencies of genes and genotypes are maintained or changed.

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2
Q

What are the four main evolutionary forces that affect allele frequency?

A
  1. Natural Selection 2. Genetic Drift 3. Mutation 4. Gene flow
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3
Q

__________ is the mechanism for a genome mutation.

A

Chromosome missegragation

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4
Q

__________ is the mechanism for a chromosome mutation.

A

Chromosome rearrangement

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5
Q

____________ is the mechanism for a gene mutation

A

Base Pair mutation

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6
Q

How many genes does each individual have?

A

25,000

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7
Q

Each new baby has a _______ risk of a new mutation at one locus.

A

2.6%

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8
Q

What is incidence equal to?

A

Incidence is twice the mutation rate

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9
Q

What is the idealized assumptions in the Hardy-Weinber Equilibrium?

A
  1. Large population mating randomly 2. allele frequencies remain constant over time because no new mutation, no natural selection and no immigration/emigration
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10
Q

What is stratification?

A

Refers to a population containing two or more subgroups which tend to preferentially mate with their own subgroup

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11
Q

What is assortive mating?

A

Refers to when the choice of mat is dependent on a particular trait

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12
Q

What are the three factors that contradict random mating?

A
  1. Stratification 2. Assortive mating 3. Consanguinity
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13
Q

__________ affect the number of chromosomes in the cell.

A

Genome mutations

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14
Q

_____________ alter the structure of individual chromosomes.

A

Chromosome Mutations

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15
Q

____________ can alter individual genes.

A

Gene mutations

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16
Q

In Huntington’s disease, the error comes from the _________

A

Father

17
Q

In fragile X syndrome, the error comes from the __________

A

Mother

18
Q

In x-linked disease, there are ________ possible male genotypes and ________ possible female genotypes.

A

Two; three