POM to P Flashcards

1
Q

Give examples of POM to P switches

A
  • amorolfine
  • atovaquone and proguanil
  • azithromycin
  • chloramphenicol
  • esomeprazole
  • levenorgestrel
  • naproxen 250mg
  • omeprazole
  • orlistat
  • sildenafil 50mg
  • sumatriptan 50mg
  • tamsulosin 400mcg
  • tranexamic acid
  • uliprisal
  • clotrimazole 2% cream
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Sildenafil (Viagra connect) OTC details

A
  • 18 + yrs, men
  • max = 8 tablets per sale, 1 tab a day
  • advise to consult GP after 6 months for review of underlying conditions
  • doesn’t work = GP
  • 1 tab (50mg) 1 hour before sex, if taken after meal onset may be delayed
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Sildenafil ADRs

A
  • reported via yellow card scheme
  • flushing, headaches, vision disturbances, dyspepsia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Don’t supply sildenafil OTC if:

A
  • taking a-blocker
  • taking enzyme inhibitors or nitrates
  • acute MI, stroke, unstable angina, severe cardiac failure in last 6 months
  • severe hepatic impairment
  • hypotension (<90/60mmHg)
  • uncontrolled HTN, valvular disease, cardiomyopathy
  • visual disorders or optic neuropathy
  • hypersensitivity
  • galactose intolerance
  • bleeding disorders/peptic ulcer disease
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Sumatriptan OTC details

A
  • for migraines with or without aura that have been diagnosed by a pharmacist or doctor
  • pt must have suffered for at least 1 year and have had at least 5 attacks
  • age 18-65 yrs
  • 1 tab (50mg) as soon as migraine starts. If this helps but migraine returns > 2 hours later - take another tab
  • if first tab doesn’t work dont take another
  • max = 2 tabs in 24 hours
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Sumatriptan ADRs

A
  • asthenia
  • dizziness
  • dyspnoea
  • flushing
  • skin reactions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Don’t supply sumatriptan OTC:

A
  • undiagnosed migraines
  • attacks that last > 24 hours
  • 4 + attacks a month
  • epilepsy
  • hepatic impairment
  • renal impairment
  • CV history
  • pregnant/breastfeeding
  • MAOI
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Omeprazole OTC details

A
  • 10mg caps for short term dyspepsia
  • 18 + years
  • 20mg OD, if symptoms improve reduce to 10mg OD
  • may take a couple of days to work
  • no improvement in 2 weeks = GP
  • if tx still required after 4 wks = GP
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Omeprazole ADRs

A
  • abdominal pain
  • constipation
  • dizziness
  • headache
  • nausea
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Don’t supply omeprazole OTC:

A
  • red flag symptoms = dysphagia, unexplained weight loss, blood in stool/vomit, abdo masses, rectal bleeding
  • over 55s with symptoms not responding to tx
  • over 45s with new/unexplained symptoms
  • recent gastric surgery
  • hepatic impairment
  • clopidogrel
  • B12 deficiency
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Orlistat (Alli) OTC details

A
  • weight loss in 18 +
  • BMI > 28 and check on each supply
  • 60mg TDS with low fat diet
  • take immediately before, during or up to 1 hour after each meal
  • OTC not exceed 6 months
  • if unable to lose weight after 12 weeks see GP
  • reduce absorption of fat soluble vits (DEAK) - take multivitamin at night
  • can cause reduced effectiveness of oral contraceptives
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Orlistat ADRs

A
  • oily stools
  • flatulence
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Don’t supply orlistat OTC:

A
  • diabetic
  • cholestasis
  • chronic malabsorption syndrome (e.g. Crohn’s/UC)
  • pregnant/breastfeeding
  • concurrent use of: oral anticoags, acarbose, ciclosporin, amiodarone, antiepileptics, levothyroxine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Tamsulosin (Flomaztra XL) OTC details

A
  • for BPH in males aged 45-75yrs
  • no improvement after 2 wks = GP
  • refer all to GP within 6 wks of OTC tx - urged to make record on patients PMR
  • can be supplied to a 3rd party except in exceptional circumstances
  • initial supply of 2 weeks, review if further 4 weeks supply required
  • pt must have had symptoms for at least 3 months
  • avoid fluids 1-2 hours before bed, avoid unnecessary use of decongestants
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Don’t supply tamsulosin OTC:

A
  • orthostatic hypotension
  • hepatic impairment
  • previous prostate surgery
  • planned cataract surgery
  • vision impairment
  • red flag symptoms: pain on urination, fever, haematuria, incontinence
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Tranexamic acid (Cyklo-F) OTC details

A
  • for heavy menstrual bleeding in aged 18-45
  • must have regular 21-35 day cycle
  • only complaint must be heavy periods
  • 2 x 500mg tabs TDS for 4 days max
  • max = 4g daily
  • take once heavy bleeding has started, dont pre-empt
17
Q

Tranexamic acid ADRs

A
  • visual disturbance (stop and see GP)
  • thromboembolic events
18
Q

Don’t supply tranexamic acid OTC:

A
  • active thromboembolic disease
  • women under 18 or over 45
  • Tx failure for 3 or more cycles
  • epileptics
  • dysmenorrhoea
  • diabetics
  • clinically obese
  • taking tamoxifen or oral contraceptives
  • red flags = irregular bleeding, haematuria, intermenstrual bleeding, post coital bleeding, pelvic pain, increase in blood loss from what is normal
19
Q

Naproxen (Feminax ultra) OTC details

A
  • for tx of dysmenorrhoea in women aged 15 - 50 years
  • dysmenorrhoea can start upto 48 hours before bleeding begins
  • 2 tabs (500mg) when pain starts, if needed, can take a further tablet 6-8 hours later
  • on 2nd and 3rd day take one tab every 6-8 hours
  • max = 3 days per cycle
  • take with/after food
  • should have tried ibuprofen/para prior to this
  • ensure not taking any other NSAIDs
20
Q

Naproxen ADRs

A

GI upset

21
Q

Don’t supply naproxen OTC

A
  • under 15, over 50
  • history of peptic ulcer disease/active GI bleed
  • respiratory conditions
  • severe HF, hepatic or renal failure
  • pregnancy
  • secondary dysmenorrhoea