Miscellaneous Flashcards
Evidence triangle order
- systematic reviews
- meta-analysis
- randomised controlled trials
- cohort studies
- case control studies
- case series
- reports
Target of statins
reduce non-HDL cholesterol by 40% in 3 months
Diabetes macrovascular complications
- CVD
- peripheral arterial disease
- peripheral vascular disease
Diabetes microvascular complications
- kidney disease
- retinopathy
- peripheral neuropathy
- autonomic neuropathy
Diabetes metabolic complications
- DKA (T1DM, within hours)
- dyslipidaemia
- hyperosmolar hyperglycaemic state (T2DM, over weeks)
Linagliptin vs sitagliptin
linagliptin better in reduced renal function
Clopidogrel and omeprazole interaction
- increased clot formation
- omeprazole reduces anti platelet effect of clopidogrel
theophylline antidote
activated charcoal
heparins antidote
protamine sulfate
Which co-morbidity increases risk of rhabdomyolysis with statins
Hypothyroidism
Ivabradine side effects
- anti - anginal drug
- Visual effects (luminous phenomena)
- Headache
- Bradycardia
- Heart block
LMWH has a lower risk of what compared to unfractionated heparin
- osteoporosis
- heparin-induced thrombocytopenia
Black person with HTN and diabetes - most appropriate HTN tx
ARB
CK monitoring with statins
only monitor at baseline and if complaint of muscle aches
Which ethnic group require a pre-treatment screening test for HLA-B*1502 allele with carbamazepine
Thai or Han-Chinese
