Polyps Flashcards

1
Q

Colonic polyps structures

A
  1. flat
  2. sessile
  3. pedunculated
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2
Q

pedunculated means?

A

pedunculated (on a stalk)

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3
Q

4 HISTOLOGIC TYPEs of Colonic polyps

A

Hyperplastic
Hamartomatous
Adenomatous
Serrated

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4
Q

Neoplastic Colonic polyps

A

Adenomatous

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5
Q

polyps Generally smaller and majority located in rectosigmoid area.

A

Hyperplastic

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6
Q

Hamartomatous

A

Associated with Peutz-Jeghers syndrome and juvenile polyposis.

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7
Q

Hamartomatous

A

Growths of normal colonic tissue with distorted architecture. Growths of normal colonic tissue with distorted architecture.

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8
Q

Hamartomatous

A

solitary lesions

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9
Q

Polyp type via chromosomal instability pathway with mutations in APC and KRAS.

A

Adenomatous

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10
Q

Adenomatous: Tubular or villous more malignant potential?

A

villous

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11
Q

Premalignant polyp via CpG hypermethylation phenotype pathway with microsatellite instability and mutations in BRAF.

A

Serrated

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12
Q

non-neoplastic polyps

A

Hyperplastic

Hamartomatous

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13
Q

“Saw-tooth” pattern of crypts on biopsy polyp type

A

Serrated

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14
Q

Polyps cz. sporadic CRC.

A

Serrated

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