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Patho Module 2 > Polycythemia > Flashcards

Polycythemia Flashcards

1
Q

What is erythropoeitin

A

hormone produced by the kidneys that plays a crucial role in red blood cell production.

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2
Q

What is the cause of polycythemia vera

A

JAK2 mutation causes RBC production without the proper protein(erythropoietin)

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3
Q

Dx testing for polycythemia vera

A

Low erythropoietin and JAK2 +

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4
Q

Signs/symptoms of polycythemia vera

A

Headache, dizziness, visual disturbances, pruritis, splenomegaly

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5
Q

Cause of secondary polycythemia

A

1)Hypoxia
2)Erythropoietin stimulating tumora
3)physiologic response to ⬇️ O2 availability (high altitude, sleep apnea, ❤️ disease)

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6
Q

Signs/ symptoms of secondary polycythemia

A

Cyanosis and clubbing

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7
Q

Lab dx for secondary polycythemia

A

⬆️Hgb & Hct
⬆️erythropoietin levels

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8
Q

Cause of Relative polycythemia

A

Decrease plasma volume ie dehydration, burns, stress

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9
Q

What labs are used to dx relative polycythemia?

A

BUN >24
Specific gravity >1.03
RBC will be normal as the polycythemia is from the low volume

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Patho Module 2 (6 decks)

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