Anemia

Question 1

Microcytic anemias (Low MCV/Hgb)

Answer 1

Iron deficiency anemia
Anemia of chronic disease
Thalassemia
Sideroblastic anemia
Lead poisoning

Question 2

Iron deficiency anemia

Answer 2

Most common
Insufficient Iron intake or chronic blood loss
S/s: brittle nails, SOB, fatigue

Question 3

Anemia of chronic disease

Answer 3

1)Associated with chronic infections, inflammation, autoimmune disease
2)Iron sequestered in macrophages
S/s:same

Question 4

Peripheral blood smear for microcytic anemia

Answer 4

Microcytic, hypochromic(pale,lack of hgb) RBCs

Question 5

Microcytic Anemia CBC

Answer 5

⬇️Hgb <12. ⬇️Hct <36%
⬇️RBC <3.5 ⬇️MCH <25.4
⬇️MVC < 80 ⬇️MCHC <31%

Question 6

Megaloblastic anemia

Answer 6

1)Characterized by presence of abnormally lrg, immature RBCs in bone marrow
2)Caused by folate or b12 deficiency

Question 7

Peripheral blood smear in megaloblastic anemia

Answer 7

1) hypersegmented neutrophils
2) macrocytes
3) variation in RBC size and shape

Question 8

CBC in megaloblastic anemia

Answer 8

Low Hgb and Hct (<12 & <36%)
High MCV and MCH (>100 & >34)
RDW: >16