Polyarteritis Nodosa Flashcards
1
Q
definition
A
auto-immune systemic inflammatory disease of the medium vessels particularly those in the muscle
2
Q
where does polyarteritis nodosa always spare
A
the lungs
3
Q
who is polyarteritis nodosa most common in
A
those with hepatitis B
4
Q
presentation
A
- peripheral neuropathy
- myalgia
- transient loss of vision
- mononeuritis multiplex
- aneurysms
- livedo reticular
- punched out skin ulcers
- hypertension secondary to activation of RAAS
5
Q
investigation
A
biopsy
6
Q
further useful investigation
A
angiogram
7
Q
management
A
IV steroids and cyclophosphamide/rituximab for 18 months and then methotrexate or azathioprine
8
Q
who can cyclophosphamide nor usually be used in
A
those with hepatitis B
