microscopic polyangiitis (MPA) Flashcards
1
Q
definition
A
auto-immune inflammatory systemic disease associated with p-ANCA and MPO
2
Q
where does MPA mostly involve
A
skin, lungs, kidneys and neuromuscular system
3
Q
presentation of MPA
A
- haemoptysis
- mononeuritis multiplex
- muscle aches
- necrotising glomerulonephritis
4
Q
test for initial suspicion of MPA
A
p-ANCA titre
5
Q
conclusive test for diagnosis
A
biopsy of any area of involvement
6
Q
what is the difference between the biopsy in MPA than in GPA
A
in MPA there are no granulomas seen
7
Q
management of MPA
A
same as for GPA
