Poisons Flashcards
Theriaca
From the Greek ‘theriakon’ meaning remedies for venomous bites
Nero
poisons his stepbrother to gain the throne
Mithridates Eupator
King of Pontus (on the Black Sea)
Is extremely paranoid of being poisoned
Mithridates takes small doses of the herbal poison/antidote to make himself immune
Mithridatism
acquired tolerance to poisons
Aconitine
Aconitum napellus
Arrow Toxins:
Alkaloids and cardiac glycosides
contain water soluble mixture of cardiac poison and muscle paralyzing poison
Charles Waterton (1820s)
Revived a donkey dead from curare poisoning by artificial ventilation using a bellows
Claude Bernard (1850s)
French physiologist
Shows that curare preparations block transmission of nerve impulses in frogs
Death is caused because the chest and abdominal muscles become paralyzed
Richard Gill
Brings back 30 pounds of curare and lobbies drug companies
Curare
competitive antagonist at nicotinic acetylcholine receptors
Physostigmine
Physostigma venenosum
Inky Cap Mushrooms
Coprinus atramentarius
Death cap mushroom
Amanita phalloides
Destroying angel
Amanita virosa