Cannabis Flashcards
Plant stems of Cannabis sativa
Source of fiber
Rope and canvas cloth
Bast fibers
Seeds of Cannabis sativa
Rich in oil, low in psychoactive chemicals
Soaps, lamp oil, paint base
Leaves and seeds of Cannabis sativa as traditional medicine
Pain relief, sleep induction, soothing agent for nervous disorders
Roots of Cannabis sativa as traditional medicine
Medieval Europe, gout
Ground-up root mixed with oil and butter
Salve to treat burns
Cannabinoids
Terpenophenolics
Nabilone
Is a synthetic cannabinoid
Mimics THC
Therapeutic use:
Antiemetic
Analgesic for neuropathic pain
THC
Tetrahydrocannabinol concentrated in resin of plant
Pure resin from Cannabis
Removed from surface of young leaves and flowers
High potency
Charas (India)
Hashish (elsewhere)
THC content: 7% - 14%
Sinsemilla
(Mexico)
Spanish, meaning without seeds
Marijuana
(USA and rest of the world)
High grade - 4% - 8% THC content
Cannabis smoking
THC, rapidly absorbed into blood
First reaches the brain
Then redistributes to rest of body
THC, metabolized in liver
THC, wide range of physiological effects on CNS
Alters the electrical properties of nerve membranes
Alters turnover rates of serotonin and dopamine
Affects prostaglandin synthesis
Medicinal use of THC
Neuralgia
Mental depression
Rheumatism
Control epileptic seizures
Types of glaucoma
The concentration of CB1 is highest in:
Basal ganglia
Globus plallidus
And Substantia nigra
The concentration of CB1 is moderate in
Cerebellum
Hippocampus
Caudate nucleus
Putamen
Hypothalamus
CB1 and CB2
Detects similar molecules
Slightly different structures
Anandamide
Essential fatty acid neurotransmitter derived from the non-oxidative metabolism of arachidonic acid
Degraded primarily by the fatty acid amide hydrolase (FAAH) enzyme which converts anandamide into ethanolamine and arachadonic acid
2-Arachidonoylglycerol
Endogenous agonist of the CB1 receptor
It is formed from arachidonic acid + glycerol
It is present at relatively high levels in the CNS
It has been found in bovine and human milk
Harry Anslinger
Racialized approach
Became illegal bc of minority groups
William Randolph Hearst
Drove change of legality in Canada
Owned plantations for forestry
Suffered because plantations were nationalized
Published articles against migrants
