Pneumonia Drugs

Question 1

Pneumonial Classifications

Answer 1

Community Acquired
Healthcare Associated
Ventilator Associated

Question 2

Community Acquired Pneumonia Causes: Out Patients

Answer 2

Strep Pneumoniae
Mycoplasma
Hemophilus

Question 3

Community Acquired Pneumonia Causes: Non-ICU Pts

Answer 3

Strep Pneumoniae
Mycoplasma
Chlamdyia Pneumoniae
Hemophilus
Legionella

Question 4

Community Acquired Pneumonia Causes: ICU Pts

Answer 4

Strep Pneumoniae
Staph Aureus
Legionella
Hemophilus

Question 5

CAP Viral Causes

Answer 5

Parainfluenza
Adenovirus
Influenza
RSV

Question 6

Antibiotic Resistant Tx: Strep Pneumoniae

Answer 6

• Fluoroquinolones
  Cipro
  Levo

Question 7

Antibiotic Resistant Tx: MRSA

Answer 7

VANCO

Question 8

CAP: Outpatients w/o Antibiotic tx in >3months

Answer 8

Macrolide (clarithromycin)
Azithromycin
Doxycycline

Question 9

CAP: Outpatients w/ Comorbidities OR antibiotics >3months

Answer 9

• Resp Fluoroquinolones (Moxi, Gemi, Levo)

- Beta-Lactacm (Amox, Augmentin, Ceftri, Cefpo, Cefuro) + Macrolide

Question 10

Anaerobes

Answer 10

Clindamycin or B-Lactam(ase inhibitor)

Question 11

MRSA

Answer 11

Vanco

Question 12

Legionella (W/ HIGH STEROIDS)

Answer 12

Erythromycin

Question 13

Pseudomonas

Answer 13

Aminoglycoside/Cipro/Levo
AND
Anti-pseudomonal Beta-Lactam

Question 14

Beta-Lactams

Answer 14

PCN
Cephalosporins
Carbapenems
Monobactams

Question 15

Protein Synth Inhibitors (30S)

Answer 15

Aminoglycosides - Gentamycin, Tobramycin, Streptomycin
**SE - Nephrotoxicity, Ototoxicity
Spectinomycin
Tetracycline - Doxycycline, Minocyclin,
**SE - Rashes, Phototoxicity, Chelating properties, Teratogenic

Question 16

Protein Synth Inhibitors (50S)

Answer 16

Macrolides - Erythro, Azithro, Clarithro
Clindamycin
-For resistant bugs - Linezolid, streptogranins

Question 17

MOA of Fluoroquinolones

Answer 17

Inhibit DNA Gyrase

Question 18

Strep Pneumoniae

Answer 18

PCN G
Amox
RESISTANT - Vanco, linezolid, HIGH DOSE Amox

Question 19

Staph Aureues

Answer 19

Ox/Clox/Diclox/Naf

RESISTANT - Vanco, Linezolid

Question 20

Hemophilus

Answer 20

Amox

RESISTANT - Augmentin, 2nd/3rd gen Cephalsporin

Question 21

Mycoplasma

Answer 21

Macrolide, Tetracycline

Question 22

Chlamydia

Answer 22

Macrolide, Tetracycline

Question 23

Legionella

Answer 23

Fluoroquinolone, Azithromycin

Question 24

Chlamydophila Psittica

Answer 24

Tetracycline

Question 25

Coxiella Burnetti

Answer 25

Tetracycline

Question 26

Francisella Tularensis

Answer 26

Doxycycline

Question 27

Yersinia

Answer 27

Strep/Gentamicin

Question 28

Anthrax

Answer 28

Cipro/Levo, Docycline

Question 29

Enterobacter

Answer 29

3rd Gen Ceph, Carbapenem

Question 30

Bordetella Pertussis

Answer 30

Macrolide

Question 31

Anaerobe

Answer 31

Beta-Lactam(ase inhibitor), clindamycin

Question 32

Protein Synth Inhibitor: Initiation Complex

Answer 32

Aminoglycosides (30S)

Linezolid (50S)

Question 33

Protein Synth Inhibitor: Peptidyl Transferase

Answer 33

Tetracyclines (30S)

Dalfopristin/Quinopristin (50S)

Question 34

Protein Synth Inhibitor: Translocation

Answer 34

Macrolides and Clindamycin (50S)

Question 35

CAP w/ Septic Shock

Answer 35

Drotecogin Alpha - Activated Protein C

Question 36

HCAP w/o risk factors or MDR

Answer 36

3rd Gen Ceph
Fluoroquinolones
Beta-Lactam
Carbapenem

Question 37

HCAP w/ Risk Factors OR MDR

Answer 37

Beta Lactam + Aminoglycoside + Linezolid/Vanco

Question 38

Failure Of Therapy B/C Of_____

Answer 38

• Incorrect Dx
• Pathogen Resistance
• Host Factors that INC mortality
• Antibiotic Resistance

Question 39

VAP: Non-MDR Bugs

Answer 39

Strep Pneumoniae
Hemophilus
MSSA
Enterobacteriaceae

Question 40

VAP: MDR Bugs

Answer 40

Pseudomonas
MRSA
Acinetobacter
Antibiotic Resistant Enterobacteriaceae