Pneumonia + Abscess + Empyema Flashcards

1
Q

What is pneumonia

A

Inflammation of gas exchange region of the lung - usually due to infection

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2
Q

When is it pneumonia rather than LRTI

A

If consolidation seen on CXR

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3
Q

What is bronchopneumonia

A

Pneumonia affects lungs and bronchi

Patchy inflammation

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4
Q

What is lobar pneumonia

A

Pneumonia fills entire lobe

More invasive organism

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5
Q

How can pneumonia be classified

A

Anatomical - lobar or broncho
Aetiological
Microbiological - type of organism

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6
Q

What are etiological

A
Community acquired
Hospital acquired 
Immunocompromised
Atypical
Aspiration - gram -ve 
Hydrostatic
Cardiac failure
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7
Q

What are common community acquired pneumonia

A

S.pneumonia = 80%
H. influenza
M. catarrhalis - immunocompromised / chronic lung

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8
Q

What are other causes

A
Kliebsella
Mycoplasma
Chlamydia
Legionella
Pseudomona - CF / bronchiectasis 
S.Aureus - CF
Anorobes
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9
Q

What is common following influenza and Rx

A

S.aureus pneumonia
- Also common if IVDU as skin contaminant
- Tends to be bibasal
Rx = flucloxacillin

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10
Q

What is HAP and Rx

A

Pneumonia 48 hours after admission to hospital

Rx = Co-amox if within 5 days or pipicellin and tazobactum if >5 days (cephalosporin / ciprofloxacin as well)

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11
Q

What are organisms causing HAP

A
Gram -ve
S.Aureus
Pseudomonas 
Klebsiella
Fungi
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12
Q

What are atypical causes of pneumonia (don’t respond to standard guidelines)

What are common organism in HIV +ve patient

A

Mycoplasma
Legionella
Chlaymdia pssitaci
Coxiella - think if farmer with flu

HIV

  • CMV
  • Cryptococcus
  • PJP
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13
Q

What causes recurrent pneumonia

A
Local obstruction - tumour
Damage - bronchiectasis
CF
COPD
Immunocompromised
Immune deficiency
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14
Q

What are the symptoms of pneumonia

A
Rapid onset
Cough 
Sputum
Pleuritic chest pain
SOB
Haemoptysis
Fever / rigors
Malaise
Anorexia
Headache
Confusion
Signs 
Tachycardia 
Tachypnoea
Cyanosis
Reduced sats 
Hypotension
CAN CAUSE SEPSIS
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15
Q

What is green / yellow suggestive of

A

Pneumococcal

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16
Q

What does rigors suggest

A

Septicaemia

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17
Q

What are chest signs

A
Crackles - focal, inspiratory, coarse 
Dullness on percussion
Bronchial breathing (consolidation)
Increased vocal resonance
Decreased expansion
Pleural rub
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18
Q

When do you get bronchial breathing

A

Consolidation

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19
Q

Who are at risk of atypical

A

Immunocompromised
Aspiration - gram -ve
Chronic lung - COPD / CF
Travel Hx

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20
Q

What do atypical organism tend to be

A

Amoxicillin resistant

Rx = clarithromycin / co-trimoxazole

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21
Q

How do you investigate pneumonia

A

O2 sats
FBC, U+E, LFT, CRP - dehydration / atypical / high WCC
WBC tend to respond faster than CRP which can be delayed
VBG for lactate
ABG if sats low to look for acidosis
CXR

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22
Q

When does CXR show

A

Areas of consolidation due to inflammatory cells
Patchy white opacity
Usually LL
Focal
Not well defined unless whole lobe affected
Air bronchogram sign - can see bronchi
Silouhette sign - diaphragm loses contrast in LL or heart loses contrast in ML

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23
Q

What do you do for higher risk of atypical patients / complications

A

Blood / sputum culture
Pneumococcal antigen
Urinary legionella antigen

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24
Q

What are other tests and when do you do them

A

Atypical serology / viral PCR / fungal culture / throat swab
CT bronchogram if ITU / immunocompromised
Pleural fluid aspiration

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25
What do fine crackles suggest
Fibrosis
26
What do coarse crackles suggest
Oedema
27
How do you treat pneumonia
``` Oxygen if hypoxic Analgesia if pleurisy Fluid balance CPAP Neb - SABA / SAMA to open up Suction if needed Anti pyretic Antibiotic Chest physio ```
28
What is standard Ax
B lactam | Macrolide
29
When would you not discharge from hospital
``` If in 24 hours 37.5 RR >24 HR >100 Systolic <90 Sats <90 Abnormal mental Inability to eat ```
30
How do you follow up after pneumonia
CXR at 6 weeks
31
Who gets pneumococcal vaccine
>65 Chronic heart / liver / lung DM Immunosuppression
32
What does CURB 65 take in
``` Used in community to decide need for admission Confusion - AMTS <8 Urea >7 - don't use in community RR >30 BP <90 or <60 Age 65 ```
33
What is a score of 0
``` Low risk Treat in community Amoxicillin 500mg TDS or If allergic Clarithromycin 500mg or Doxycycline 100mg BD with 200mg loading ```
34
What is a score of 1
Do O2 sats + CXR If sats low or CXR shows bilateral shadows = admit to hospital Same as above
35
Score of 2
Hospital Rx Amoxicillin + Clarithromycin / levofloxacin
36
Score of 3+
Consider ITU Coamoxiclav 1g TDS Ceftriaxone 1.5g TDS Tazobactam + Clarithromycin + levofloxacin
37
What are complications of pneumonia
``` Sepsis AKI Pleural effusion Pneumothorax Atelactasis Fibrosis if doesn't clear Empyema Lung Abscess ARDS Type 1 resp failure AF Bronchiectasis ```
38
When would infection not clear
COPD | Bronchiectasis
39
What is abscess common in
Klebsiella | Staph if Hx of influenza
40
What is haemolytic anaemia common in
Mycoplasma
41
How does pneumonia progress
``` 1 week fever resolves 4 week chest pain and sputum stop 6 week cough and Sob reduced - follow up CXR 3 months = fatigue 6 months = normal ```
42
Differential
``` TB Lung cancer - CXR PE CF Pulmonary vasculitis ```
43
How do you treat respiratory failure
High flow O2 Transfer to ITU if CO2 rises or hypoxia doesn't improve Aim sats 94-98%
44
What causes hypotension
Dehydration | Vasodilation due to sepsis
45
How do you treat
If systolic <90 = fluid challenge 250ml of crystalloid over 15 minutes Central line + IV to maintain Inotropic support in ITU
46
What is empyema and what causes
``` Pus in pleural space May see pleural effusion on CXR - Pneumonia - Abscess - Post-op / trauma - OM ```
47
When do you suspect empyema
``` Pneumonia resolving but fever persisting Chest pain Fever SOB No cough ```
48
How do you Dx + treat | What is seen on aspirate
``` Pleural aspiration - Yellow - pH <7.2 - Decreased glucose - Increased LDH CXR = pleural effusion Bronchoscopy ``` Rx - IV Ax - Chest drain - Surgical excision
49
What is a lung abscess and what are common organisms
``` Cavitating area of local infection caused by Pneumonia Aspiration Lung cancer Obstruction Infarction PE Septic emboli - IVDA ``` S.aures post influenza Pseudomona Klebsiella
50
What are features of abscess
``` Swinging fever Cough Purulent sputum Pleuritic pain if discharge into pleural space Haemoptysis Lethargy Weight loss Clubbing Anaemia Crepitations ```
51
How do you Dx abscess
FBC, CRP, culture Sputum microscopy and culture and cytology CXR CT to exclude obstruction
52
How do you treat abscess
``` Ax until healed (minimum 6 weeks) Postural drainage Percutaenous drainage Repeated aspiration Surgical excision Intrapleural tPA/DNase to break down adhesions ```
53
When is AF common
Elderly Improves with Rx Can use BB or digoxin to slow
54
What are rare complications of pneumonia
Myocarditis Pericarditis Meningitis Jaundice 2 to Ax or sepsis
55
What do atypicals tend to do
Don't respond to cephalosporin / penicillin Affect upper lobe Associated LN and deranged LFT
56
Klebsiella pneumonia
Form abscess and empyema | Red current jelly sputum
57
Who is Klebsiella common in
Alcohol DM Elderly
58
Who is pseudomonas common in
``` Bronchiectasis CF ITU HAI As resistant to Ax which these people are on ```
59
How does PJP (fungal) present
``` Dry cough no sputum SOB on exertion Fever Night sweats Exercise induced desaturations Absent chest signs Pneumothorax Bilateral infiltrates ```
60
How do you Dx
CXR = bilateral consolidation | BAL as sputum doesn't pick up with silver stain - often needed
61
How do you treat PJP
IV pentandimine Co-trimoxazole Prophylaxis if severely low CD4 Steroid if severe hypoxia
62
How does mycoplasma present
``` Flu like Dry cough Erythema multiform rash Neuro Sx in young patient Atypical CXR - bilateral Bilateral consolidatin ```
63
How do you Dx mycoplasma
Viral throat swab PCR sputum Cold agglutinins IGM
64
How do you Rx mycoplasma
Macrolide - clarithromycin or doxycycline
65
What are complications of mycoplasma
``` Erythema multiform / nodosum Deranged LFT Haemolytic anaemia ITP Encephalitis Myocarditis GBS - weakness / loss of reflexes Hepatitis Pancreatitis Acute GN ```
66
How does legionella present
``` Flu like Dry cough Brady Confusion Hyponatrameia Abnormal LFT D+V Lymphopenia PLeural effusion Renal failure Haemolytic anaemia Can get hepatitis ```
67
When do you think of Legionella
After holiday to Spain | Contact with infected water etc
68
How do you Dx
Urinary antigen in urine sample
69
How do you Rx
Erythromycin
70
How does psittacosis present
``` Fever FLu Conjunctivitis Dry cough Hx of bird contact Severe headache No response to penicillin ```
71
How do you treat
Tetracycline | Macrolide 2nd line
72
Complications of psittacosis
``` Meningoencephalitis IE Hepatitis Nephritis Splenomegaly ```
73
How does chlamydia pneumonia present
Pharyngitis Hoarse Otits media Pneumonia
74
How do you treat
Doxycline or clarithromyin
75
What does ezithromycin give you
Very sick stomach
76
What puts you at risk of aspiration pneumonia
``` Neurological - poor swallow Stroke MS Spinal cord injury Alcohol intoxication Poor dental hygiene Prolonged hospital Achalasia Reflux Intubation Impaired consciousness Impaired mucociliary clearance ```
77
What is common organism
Klebsiella - red current jelly S.Pneumonia S.Aureus H.influenza
78
What suggest aspiration
R lower lobe | Absence of fever
79
How do you monitor response to Rx
CRP
80
What do you give to break down adhesions caused by empyema / abscess
Intrapleural tPA/DNase
81
why does post-op pain increase risk of pneumonia
Shallow breathing