COVID Flashcards
What is the name of COVID virus
SARS COV-2 beta coronavirus
What type of virus
RNA
What other epidemics have been caused by coronavirus
SARS - SARS-COV
MERS
What is a pandemic
Worldwide spread
How is COVID spread
Droplet
Has been detected in stool / ocular secretion / blood
When are you infectious
6 days prior to Sx
Declines after 7 days of symptoms
When is peak infectious
1 day of symptoms
What is incubation
14 days but majority = 4
What can occur after infection
RNA sheeding
Not infectious when this happens but may be V+e
What are Sx
Asymptomatic Pneumonia - cough / SOB / fever Myalgia Headache Sore throat Anosmia N+V Diarrhoea Covid toe due to clot in microvascular
What is 3 different courses
Multi-organ failure with rapid deterioration at day 5-7 due to cytosine
Stable with asymptomatic hypoxia requiring CPAP or help
Delerium - common in elderly
Who is at increased risk
CO-morbid
CVS
DM
HTN
What is associated with poor prognosis
Lymphopenia (low lymphocyte even if high WCC) AKI Elevated liver enzyme Increased lDH Raised inflammatory - CRP / ferritin D-dimer increased Increased PT Increased troponin
How do you image
CXR
CT if stable
What would you see
Bilateral
Lower zone
Ground class appearance
Consolidation
What multi-system involvement
Pneumonia ARDS VTE Cardiomyopathy in heart - may think MI but don't respond Kawasaki in children Transamintiis in liver Delerium Stroke Anosmia GBS
How do you test
Nasopharyngeal swab - detect RNA on PCR
Ab testing
How do you treat
Largely supportive O2 High flow nasal CPAP or BiPAP Invasive VTE prophylaxis Nutrition Dexamethasone Early mobilisation Proning
What is more used CPAP or BiPAP
CPAP as COVID causes type 1 resp failure
BiPAP more used in type 2
What is danger
Risk of aerosol generation as not closed circuit like intubation
What does pneumonitis cause
Fine inspiratory crackles in check like fibrosis
What else can you give
Ax incase bacterial infection underneath
If worsening but CXR normal what would you expect
PE
Treat as may not be stable enough for CTPA
What are CI to posing
Unstable cervical spine
Pregnancy
Unable to get into position indepently
More
Would you treat if -ve swab
If Sx suggestive e.g. lymphopenia