Pneumonia Flashcards

1
Q

What is pneumonia?

A

Infection and inflammation of the alveoli

Pneumonia can be caused by various pathogens including bacteria, viruses, and fungi.

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2
Q

What does the acronym SALAMI stand for in pneumonia risk factors?

A
  • S: Smoking
  • A: Advanced age (over 60)
  • L: Lung diseases or cancer
  • A: Alcohol
  • M: Malnutrition
  • I: Immunocompromised

Immunocompromised individuals may include IV drug users and those with HIV or on antibiotic and cytotoxic drug use.

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3
Q

What are the most common bacterial infections associated with pneumonia?

A
  • Strep pneumoniae
  • Haemophilus influenzae b

These bacteria are often responsible for community-acquired pneumonia.

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4
Q

Which bacteria are associated with pneumonia in immunocompromised or chronic lung disease patients?

A

Moraxella

Moraxella is particularly noted in patients with weakened immune systems.

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5
Q

What bacteria are commonly found in cystic fibrosis patients with pneumonia?

A
  • Pseudomonas aeruginosa
  • Staphylococcus aureus

These pathogens can lead to severe lung infections in cystic fibrosis patients.

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6
Q

What is the primary bacterial cause of pneumonia in bronchiectasis patients?

A

Staphylococcus aureus

Staphylococcus aureus is often implicated in pneumonia for bronchiectasis patients.

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7
Q

What is the definition of hospital-acquired pneumonia?

A

Pneumonia that occurs 48 hours or more after hospital admission and is not present at the admission time

Hospital-acquired pneumonia is often more resistant to treatment due to the pathogens involved.

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8
Q

Define community-acquired pneumonia.

A

Pneumonia contracted in a community setting, not hospital or healthcare facility or nursing homes

This type of pneumonia is generally more common and may be less severe than hospital-acquired pneumonia.

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9
Q

What causes foreign body aspiration pneumonia?

A

Inhalation of a foreign object into the lungs

This type of pneumonia can occur in individuals of all ages, particularly in young children.

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10
Q

What is pneumocystis jiveci pneumonia?

A

A fungal infection that occurs in immunocompromised patients, e.g., poorly controlled HIV

This type of pneumonia is characterized by specific symptoms and requires antifungal treatment.

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11
Q

What are the three signs of pneumocystis jiveci pneumonia?

A
  • Dry cough
  • Shortness of breath on exertion
  • Night sweats

These symptoms are indicative of the infection in immunocompromised individuals.

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12
Q

What is an atypical infection that causes pneumonia associated with infected water systems?

A

Legionella pneumophila

Example: AC systems

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13
Q

What is the hallmark feature of Legionella pneumophila infection?

A

Syndrome of Inappropriate ADH (SIADH) causing hyponatremia

Perform urine antigen test

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14
Q

What atypical infection is associated with infected birds?

A

Chlamydia psittaci

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15
Q

What is the hallmark feature of Mycoplasma pneumoniae infection?

A

Erythema multiforme and neurological symptoms

Occurs in approximately 43% of cases

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16
Q

What atypical infection is common in school-age children?

A

Chlamydia pneumoniae

17
Q

What is Q fever caused by?

A

Coxiella burnetii

Transmitted through infected bodily fluids of animals, e.g., farmers

18
Q

What are common pneumonia presentations?

A

Productive cough, fever, shortness of breath (SOB), malaise, acute confusion, haemoptysis, pleuritic chest pain

19
Q

What are physical examination findings in pneumonia?

A

Bronchial breath sounds, focal coarse crackles, dullness to percussion

20
Q

What are the complications of pneumonia represented by SLAP HER?

A

S: SIADH and hyponatremia
L: Lung abscess
A: ARDS
P: Parapneumonic effusion
H: Hypotension
E: Empyema
R: Respiratory or renal failure

21
Q

What investigations are used for pneumonia?

A

CXR: Consolidation
FBC: Raised WBC count
CRP level: Raised
U&Es: Urea level and acute kidney injury
Microbiology: Sputum cultures, blood cultures

22
Q

What does CURB-65 stand for in pneumonia scoring?

A

C: Confusion
U: Urea more than 7 mmol/L
R: Respiratory rate 30 or more
B: Blood pressure: systolic less than 90 OR diastolic equal to or less than 60
65: Age 65 or over

23
Q

What is the total score range for CURB-65?

A

Ranges from 0-4

0/1: Low risk so can be treated at home
2: Moderate risk so should assess and consider hospital admission
3/4: High risk, give immediate hospital referral so should be admitted to intensive care

24
Q

What is the management for hospital-acquired pneumonia?

A

PO doxycycline 200 mg on the first day then 100 mg once a day for 4 days (total course of 5 days)

25
What is the management for community-acquired pneumonia?
Amoxicillin PO 500 mg three times a day for 5 days
26
What is the second-line treatment for pneumonia?
PO doxycycline 200 mg on the first day then 100 mg once a day for 4 days (total course of 5 days)
27
What is the treatment for Pneumocystis jiroveci pneumonia?
Co-trimoxazole
28
What is the management for foreign body aspiration pneumonia?
Bronchoscopy to remove foreign body, antibiotic course
29
What are the treatments for atypical pneumonia?
Macrolides (e.g., clarithromycin), fluoroquinolones (e.g., levofloxacin) and tetracyclines (e.g., doxycycline)
30
Why is penicillin ineffective for certain pneumonia types?
Can't be cultured with gram staining, so penicillin is ineffective
31
What are general measures for pneumonia management?
Smoking cessation, up to date vaccinations