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MIDTERMS > PMQA LAB - MIDTERM > Flashcards

PMQA LAB - MIDTERM Flashcards

1
Q

Manufacturing Order #8

A

Chalk Mixture

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2
Q

Chalk Mixture

Standard Qty:
Actual Order:

A

100mL

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3
Q

Chalk Mixture Raw Materials + Uses (5)

A

1.CALCIUM CARBONATE - ACTIVE INGREDIENTS
2.TRAGACANTH - VISCOSITY ENHANCER
3.SYRUP - SUSPENDING VEHICLE
4.CINNAMON WATER - ANTIBACTERIAL PROPERTY
5.CHLOROFORM - WATER SOLVENT

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4
Q

Chalk Mixture |
Chemical Name
Other Name
Generic Name

A

CHEMICAL NAME : CALCIUM CARBONATE (CACO3)
OTHER NAME : CALCI-AID, CALCI-CHEW ,TUMS
GENERIC: CALCIUM CARBONATE

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5
Q

Chalk Mixture |
Pharma Classification
Common Condition

A

PHARMACEUTICAL CLASSIFICATIION:
ANTACID , MINERAL & ELECTROLYTES

Common conditions :
ACID INDIGESTION, HEART BURN AND STOMACH UPSET FOR CALCIUM DEFICIENCY

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6
Q

Chalk Mixture |
Brand Name:

A

Calci-Chew, Oysco 500, Os-Cal 500, Oyst Cal 500, Oyster Shell Calcium 500,

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7
Q

Chalk Mixture Mixture |
Dosage Forms

A

oral suspension (1250 mg/5 mL),
oral tablet (1250 mg; 600 mg; 648 mg),
oral tablet, chewable (1000 mg; 1177 mg; 400 mg; 420 mg; 500 mg; 550 mg; 600 mg; 750 mg; 850
mg; base 500 mg)

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8
Q

Precautions abt Chalk Mixture

A
  • kidney disease;
  • kidney stones;
  • cancer;
  • a parathyroid gland disorder; or
  • high levels of calcium in your blood.
  • Ask a doctor before using calcium carbonate if you are pregnant or breastfeeding. Your dose needs may be different during pregnancy or while you are nursing.
  • Store at room temperature away from moisture and heat. Do not freeze
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9
Q

Chalk Mixture | Warning
AVOID FOODS HIGH IN _____ LIKE SPINACH OR _____ LIKE BRAN & AND WHOLE GRAINS MAY
DECREASE CALCIUM ABSORTION.

A

Oxalic Acid; Phytic Acid

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10
Q

Chalk Mixture | BEST TAKEN WITH _____FOR FASTER ABSORPTION OF CALCIUM

A

VITAMIN C OR ORANGE JUICE

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11
Q

Chalk Mixture | Dosage Regimen
TAKEN WITH FOOD LESS THAN _____ PER DAY

A

600MG

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12
Q

Chalk Mixture | Side Effects

A

VOMITING,CONSTIPATION,DRY MOUTH , INCREASE URINATION , LOSS OF APPETITE

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13
Q

Chalk Mixture |
Store at _____ temperature away from moisture and heat. Do not ____

A

room ; freeze

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14
Q

MANUFACTURING PRODUCT #9

A

MINERAL OIL EMULSION

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15
Q

MINERAL OIL EMULSION |
STANDARD QUANTITY:
ACTUAL ORDER QUANTITY :

A

STANDARD QUANTITY: 1000ML
ACTUAL ORDER QUANTITY : 250ML

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16
Q

MINERAL OIL EMULSION INGREDIENTS (5)

A
  1. MINERAL OIL - ACTIVE INGREDIENTS
    2.ACACIA - EMULSIFYING AGENT
    3.SYRUP - VEHICLE
    4.VANILLIN - FLAVORANT
    5.PURIFIED WATER - SOLVENT
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17
Q

Mineral Oil Emulsion
CHEMICAL NAME :
PHARMACEUTICAL CLASSIFICATION:

A

CHEMICAL NAME : MINERAL OIL
PHARMACEUTICAL CLASSIFICATION: LAXATIVE

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18
Q

_______is a lubricant laxative that works by coating the waste matter inside your intestines to
help seal in water. When too much water seeps out of your stools they can become hard and cause
constipation.

A

Mineral Oil Emulsion

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19
Q

______ (applied in the rectum) is used to treat constipation.

A

Mineral Oil Emulsion Rectal

20
Q

Preparation of Emulsion (3)

A

-Wet gum method
-Dry gum method
-Bottle method

21
Q

Emulsifier is triturated with the oil in perfectly dry porcelain mortar.

Water is added at one triturated immediately, rapidly and continuously (until get a clicking sound and thick white cream is formed, this is the primary emulsion)

the remaining quantity of water is slowly added to form the final emulsion

A

Continental or Dry Gum Method

22
Q

As the name implies, in this method first gum and water are triturated together to form a mucilage. The required qty of oil is then added gradually in small proportions with thorough trituration to form the primary emulsion.

Once the primary emulsion has been formed remaining quantity of water is added to make the final emulsion.

A

Wet Gum Method

23
Q

It is extemporaneous preparation for volatile oils or oil with low viscosity.

Water (volume equal to oil) is added in portions with vigorous shaking to form primary emulsion

the remaining quantity of water is added to make the final emulsion

A

Bottle or Forbes Bottle Method

24
Q

Dry Gum Method aka

A

Continental Method

25
Q

Wet Gum Method aka

A

English Method

26
Q

Forbes Bottle Method

A

Bottle Method

27
Q

are widely used in the pharmaceutical industry to prepare lotions and creams that can be absorbed by the body
easily.

A

Emulsions

28
Q

Commonly used disinfectants like _____, when poured in water, works as oil-in-water type emulsion

A

phenyl

29
Q

The emulsification process helps in the ____process of the human body

A

digestion

30
Q

Emulsions like _____ are a type of coolant used in metalworking

A

cutting fluid

31
Q

This test can be conducted by adding water or oil to the emulsion. If water is added, and it gets
mixed with the emulsion, then the emulsion is of the oil-in-water (o/w) type. If water does not mix with the emulsion, then it is known as the water-in-oil (w/o) type. Apart from water, if oil is added to the emulsion, and it gets mixed, then it is called the water-in-oil type.

A

Dilution Test

32
Q

This test can be conducted by adding a water-soluble dye to the emulsion. If the
emulsion becomes red, it means that it is the oil-in-water type and vice-versa.

A

Dye Solubility Test

33
Q

In this test, some amount of electrolyte is added to the emulsion to measure its
conductance. If it shows an increase in conductance, the emulsion is of the oil-in-water type. On the other
hand, if there is no change in conductance, the emulsion is water-in-oil type

A

Conductivity Test

34
Q

According to this theory, the emulsifying agent makes a film over one stage, which leads to forming globules, and these globules repel each other, and the repulsive force between them forces them to remain suspended in the dispersion medium

A

Repulsion Theory

35
Q

According to this theory, emulsification is a process that arises by the reduction of interfacial tension between the two mediums.

A

Surface Tension Theory

36
Q

Do not give mineral oil oral emulsion to a child younger than ____ of age. Tell your doctor if you are breast-feeding.

A

6 years

37
Q

Mineral Oil Emulsion is sometimes used to remove _______ from your colon after you have undergone a CT scan or other radiologic (x-ray) examination of your intestines.

A

Barium residue

38
Q

An emulsion contains small droplets of oil that are dispersed in water.

A

Oil-in-water

39
Q

An emulsion has small droplets of water that are dispersed in an oil.

A

Water-in-oil

40
Q

Used to aid in the processing of foods and also to help maintain quality and freshness.

A

Emulsifiers

41
Q

In ______, emulsifiers can help to prevent the growth of moulds which would happen if the oil and fat separated,

A

low fat spreads

42
Q

A colloidal mixture of two or more liquids that normally don’t mix,

A

Emulsion

43
Q

Examples of Emulsion (5)

A

Mayonnaise
Butter
Milk
Salad Dressing
Moisturizer

44
Q

Example of Pharmaceutical Emulsion (2)

A

-Scott’s Emulsion
-Frelax

45
Q

Example of Pharmaceutical Emulsion (2)

A

-Scott’s Emulsion
-Frelax

MIDTERMS (8 decks)

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