Pleural Effusion Flashcards
Excess quantity of fluid in the pleural space which should normally contain a very thin layer of fluid
Pleural effusion
Etiology of pleural effusion
Pleural fluid formation > pleural fluid absorption
*Decreased lymphatic drainage
Due to alteration of SYSTEMIC factors that influence formation and absorption of pleural fluid
Transudative
Due to alteration of LOCAL factors that influence the formation and absorption of pleural fluid
Exudative
Leading causes of transudative effusion
LV failure: MC
cirrhosis
Leading causes of exudative effusion
Bacterial pneumonia
Malignancy
Viral Infection
Pulmonary Embolism
Light Criteria (exudative effusions)
PF/serum protein >0.5
PF/serum LDH >0.6
PF LDH >2/3 upper normal serum limit
At least one
Considerations for increased amylase
Esophageal rupture
Pancreatic pleural effusion
Malignancy
Considerations for glucose <60 mg/dL
Malignancy
Bacterial Infections
Rheumatoid pleuritis
Diagnostic modality if no diagnosis and no improvement of symptoms
Thoracoscopy or Open pleural biopsy
Serum-PF gradient likely to be transudative
> 31 g/L
Indications for diagnostic thoracentesis in effusion due to heart failure
Unilateral or unequal effusion, (+) fever, (+) pleuritic chest pain
Measurement if effusion persists despite therapy
Pleural fluid proBNP
> 1500 diagnostic of CHF
Mechanism of hepatic hydrothorax
Direct movement of peritonea fluid through small holes in the diaphragm into the pleural space
MC exudative pleural effusion
Parapneumonic