Occupational and Environmental Lung Diseases Flashcards

1
Q

Small rounded opacities in CXR

A

Silicosis

Coal worker’s

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2
Q

Small linear opacities in CXR

A

Asbestosis

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3
Q

Water soluble gases predilection

A

Ammonia and sulfur dioxide: lining of upper and proximal airways

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4
Q

Less soluble gases predilection

A

Nitrogen dioxide and Phosgene: bronchioles and alveoli: life-threatening

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5
Q

Particles ~2.5 to 10um

A

Coarse-mode fraction: tracheobronchial tree

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6
Q

Particles <2.5 um

A

fine-mode fraction: lower airways

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7
Q

Particles <0.1 um

A

Remain in the airstream

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8
Q

Inorganic Dusts

A
Asbestos
Berrylium
Silica
Coal dust
Other metals
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9
Q

Organic dusts

A
Toxic chemicals
Grain dust
Cotton dust
Other agricultural dusts
Other respi environmental agents
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10
Q

Diffuse interstitial fibrosing of the lung directly related to intensitu and duration of exposure of pipe-fitters, boilermakers, exposure to friction materials

A

Asbestosis

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11
Q

Mechanism of asbetosis

A

Oxidative injury

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12
Q

PFT in asbestosis

A

Restrictive

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13
Q

MC cancer associated with asbestosis

A

Lung Ca associated with smoking

Mesothelioma (not associated with smoking)

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14
Q

At risk of exposure are those in mining, stone cutting, employment in abrasive industries, foundry work, packing of silica flour and quarrying

A

Silicosis

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15
Q

“Crazy paving” in HRCT

A

Acute silicosis: ~10 months of heavy exposure

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16
Q

Treatment of acute silicosis

A

Whole-lung lavage

17
Q

“Egg shell pattern” in CXR

A

Simple silicosis: 15-20 years exposure

18
Q

PFT in complicated silicosis

A

Restrictive and Obstructive

19
Q

Caplan’s syndrome

A

Coal miners with silicosis + seropositive RA + pneumoconiotic nodules

20
Q

More common berrylium exposure

A

Chronic granulomatous inflammatory disease

21
Q

PFT of beryllium disease

A

Restrictive and/or obstructive

22
Q

Risk associated with cotton dust

A

Byssinosis

23
Q

Monday chest tightness

A

Byssinosis