Pleural Effusion Flashcards

1
Q

What is pleural effusion?

A

Collection of fluid in the pleural cavity

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2
Q

What are the two types of pleural effusion?

A

Exudative
Transudative

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3
Q

What does it mean for pleural effusion to be exudative?

A

A high protein count (>3g/dL)

Related to inflammation

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4
Q

What does it mean for pleural effusion to be transudative?

A

A lower protein count (<3g/dL)

Fluid moving across into the pleural space (trans- meaning moving across). Think of the causes of fluid shifting

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5
Q

What are exudative causes?

A

Lung cancer
Pneumonia
Rheumatoid arthritis
Tuberculosis

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6
Q

What are transudative causes?

A

Congestive cardiac failure
Hypoalbuminaemia
Hypothroidism
Meig’s syndrome (right sided pleural effusion with ovarian malignancy)

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7
Q

Presentation

A

Shortness of breath
Dullness to percussion over the effusion
Reduced breath sounds
Tracheal deviation away from the effusion if it is massive

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8
Q

What will a CXR show

A

Blunting of the costophrenic angle

Fluid in the lung fissures

Larger effusions will have a meniscus.

This is a curving upwards where it meets the chest wall and mediastinum.

Tracheal and mediastinal deviation if it is a massive effusion

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9
Q

What is the treatment of pleural effusion?

A

Pleural aspiration - sticking a needle in and aspirating the fluid
Thoracocentesis

Chest drain - drain effusion and prevent it recurring

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10
Q

When it Light’s criteria used in the diagnosis of pleural effusion?

A

If pleural fluid protein is 25-35g/L, Light’s criteria are used to distinguish transudative from exudative pleural effusions.

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11
Q

What does Light’s criteria state?

A

The fluid is an exudate if one or more of the following criteria are met:

Pleural fluid protein divided by serum protein is >0.5
Pleural fluid LDH divided by serum LDH is >0.6
Pleural fluid LDH is >⅔ the upper limit of the laboratory normal value for serum LDH

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12
Q

What would be seen in clinical examination?

Peripheral

A

Nicotine staining of fingers

Clubbing (lung cancer)

Evidence of joint deformity (rheumatoid arthritis)

Signs of fluid overload (heart failure)

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13
Q

What would be seen in clinical examination?

Closer inspection of chest

A

Reduced chest movement on the affected side

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14
Q

What would be seen in clinical examination?

Palpation

A

Tracheal deviation away from affected side

Reduced chest expansion on affected side

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15
Q

What would be seen in clinical examination?

Percussion and auscultation

A

Sounds ‘stony’ dull.

When auscultating, breath sounds and vocal resonance are reduced or absent over an effusion.

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16
Q

What are pleural tumours?

A

Malignant - poor outcome

Primary malignancy: mesthoelioma

17
Q

What is mesothelioma?

A

A rare agressive cancer

Commonly found in men - those who work as plumbers, electricians, shipbuildings, power plants, boilers and engines

18
Q

How does mesothelioma happen?

A

Inhaled asbestos fibres reach the pleura and cause inflammation provokes tumour formation

19
Q

Mesothelioma diagnosis

A
  • CT Thorax and Biopsy: needed to stage (gauge extent eg any distant spread ect)
  • Thickened pleura, pleural nodules or masses, pleural plaques, an effusion, soft tissue infiltration
20
Q

Features of pleural pressure

A
  • Subatmospheric
  • -3 to -5cm of water
  • Gradient: apex to base
21
Q

What are the three pleural problems?

A
  • Collection of fluid: Pleural Effusion
  • Collection of Air: Pneumothorax
  • Pleural Malignancy: Mesothelioma
22
Q

Investigations

A

First line CXR - needs 100/200ml for visualisation
US more sensitive

Pleural fluid analysis - Aspiration, inspect fluid

23
Q

Management

A

pH < 7.2 = suggest pnuemonia -> chest drain

Transduative - treat underlying cause

Exudative - treat infection/further imaging + biopsy cause not identified