Platelet Aggregation Inhibitors

Question 1

What do the platelet aggregation inhibitors inhibit ?

Answer 1

Question 2

Platelet aggregation inhibitors are beneficial in what

Answer 2

Question 3

List the platelet aggregation inhibitors

Answer 3

Aspirin
Thienopyridines
Blockade of platelet glycoprotein IIb/IIIa receptors
Dipyridamole

Question 4

What is the mechanism of action of aspirin

Answer 4

Question 5

What is the difference between aspirin and other NSAIDs and salicylates

Answer 5

Question 6

What are the side effects of aspirin

Answer 6

Question 7

Explain combination therapy of aspirin

Answer 7

Question 8

List the thienopyridines

Answer 8

Question 9

Explain the mechanism of action of thienopyridines

Answer 9

Question 10

Explain the pharmacokinetics of ticlopidine and clopidogrel

Answer 10

Question 11

Explain the CYP2C19 genotyping individuals

Answer 11

Question 12

What are the uses of ticlopidine

Answer 12

Question 13

What are the uses of clopidogrel

Answer 13

Question 14

What are the side effects of ticlopidine

Answer 14

Question 15

What are the side effects of clopidogrel

Answer 15

Question 16

List the blockade of platelet glycoprotein IIb/IIIa receptors

Answer 16

Question 17

What is the mechanism of action of the blockade of platelet glycoprotein IIb/IIIa receptors

Answer 17

Question 18

What is the therapeutic use of the blockade of platelet glycoprotein IIb/IIIa receptors

Answer 18

Question 19

What is the adverse effect of the blockade of platelet glycoprotein IIb/IIIa receptors

Answer 19

Question 20

What is the additional anti-platelet directed drug

Answer 20

Dipyridamole

Question 21

Explain the combination therapy of dipyridamole

Answer 21