Plague Flashcards

1
Q

What were the three major plague pandemics?

A

Justinian Plague
Black Death
Modern plague

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2
Q

When was the Black Death?

A

1347

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3
Q

When was the Justinian Plague?

A

541

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4
Q

When was the modern plague?

A

1894

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5
Q

What the plague caused by?

A

Y pestis (bacteria)

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6
Q

Where does the Y Pestis habituate?

A

Stomach of a flea at ambient temp

Blood or tissue it mammalian host

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7
Q

Who are the natural hosts if the plague?

A

Rats and other rodents

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8
Q

What are symptoms of the plague?

A

Flu like
Body aches
Fever
Vomiting

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9
Q

What are the three forms of the plague?

A

Bubonic plague
Septicemic plague
Pneumonic plague

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10
Q

What happens during bubonic plague?

A

Bacteria enters body and multiplies at site of entry
Lymph nodes infected and swell
Fever
Sites of infection may burst

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11
Q

What’s the most common form of the plague?

A

Bubonic

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12
Q

What plague is Black Death?

A

Septicaemic plague

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13
Q

What happens during septicaemic plague?

A

Flea bite if direct contact with infected material
Infection spreads in blood
Blood clots and organ failure

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14
Q

What happens during pneumonic plague?

A

Person to person contact
Infection spreading to the lungs
Can’t take in oxygen
Sepsis and toxic shock

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15
Q

What are the ways of plague transmission?

A

Flea bites
Contact with contaminated tissue
Infectious droplets

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16
Q

How is the plague diagnosed?

A

Visualisation of bipolar staining

17
Q

What are sourced of bi polar staining?

A

Lymph nodes
Blood
Sputum
Bronchial washing

18
Q

How can plague be treated?

A

Antibiotics

19
Q

How long does it take for pneumonic plague to kill?

A

18-24 hours

20
Q

How is plague prevented?

A

Quarantine
Vaccines
Avoid direct contact
Rodent control

21
Q

What did Y pestis diverge from?

A

Y pseudotuberculosis