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Infection and Immunology > Adaptive Immune System > Flashcards

Adaptive Immune System Flashcards

1
Q

What are features of the adaptive immune system?

A

Specific to certain antigens
Gained after exposure
Delay before effective
Memory

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2
Q

What is adaptive system carried out in?

A

Lymphatic system

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3
Q

Who can carry out adaptive immune systems?

A

Vertebrates

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4
Q

What cells are in the adaptive immune system?

A

Lymphocytes
Cytotoxic T cells
T helper cells
B cells

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5
Q

Where do lymphocytes originate?

A

Bone marrow

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6
Q

Where do T cells mature?

A

Thymus

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7
Q

Where do B cells mature?

A

Bone marrow

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8
Q

What are the secondary lymphoid organs?

A

Lymph nodes

Spleen

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9
Q

What do lymph nodes filter?

A

Lymph

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10
Q

What does the spleen filter?

A

Blood

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11
Q

What are examples of APC?

A

Dendritic cells
B cells
Macrophages

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12
Q

What’s the humoral defence?

A

Defend against pathogens and toxins in extracellular fluid

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13
Q

What cells are involved in humoral defence?

A

B cells

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14
Q

What’s the role of cell mediated response?

A

Defence against infected cells, cancer cells and transplants

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15
Q

Who carries out cell mediated response?

A

T cells

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16
Q

What’s an epitope?

A

Antigenic determinant

17
Q

Where are B and T cell receptors?

A

In their plasma membranes

18
Q

How many antigen epitope is a B or T cell specific for?

A

1

19
Q

Which cells are removed when B cells undergo selection process when developing?

A

Self reactive cells

20
Q

What are the types of antibodies produced?

A 
IgM 
IgD
IgE
IgA
IgG
21
Q

Which Ig is the first to be further after antigen exposure?

A

IgM

22
Q

What two processes do T cells go under?

A

Positive selection

Negative selection

23
Q

What T cells get selected?

A

Cells that’s don’t recognise self MHC

Cells that recognise self MHC too strongly

24
Q

How do T cells get activated?

A

By recognition of antigen presented on MHC molecules

Infection and Immunology (11 decks)

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