PJE Spotter Qs & EoW Qs (also copied to qs) Flashcards

1
Q

This is a photograph of the lower back of a one day old baby who is still in hospital. What is the most likely cause of this lesion?

  1. Child abuse
  2. Blood coagulation defect
  3. Meningicoccal septicaemia
  4. Strawberry haemangioma
  5. Mongolian blue spot
A

This is a photograph of the lower back of a one day old baby who is still in hospital. What is the most likely cause of this lesion?

  1. Child abuse
  2. Blood coagulation defect
  3. Meningicoccal septicaemia
  4. Strawberry haemangioma
    5. Mongolian blue spot

Dermal melanocytosis is the name of a kind of birthmark that is flat, blue, or blue-gray. They appear at birth or in the first few weeks of life. Dermal melanocytosis was formerly called Mongolian blue spots

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2
Q

This centile chart shows the weight of a newborn baby plotted against gestation. The baby is

  1. extremely low birthweight
  2. small for gestational age
  3. normal birthweight
  4. low birthweight
  5. very low birthweight
A

This centile chart shows the weight of a newborn baby plotted against gestation. The baby is

  1. extremely low birthweight
  2. small for gestational age
  3. normal birthweight
    4. low birthweight
  4. very low birthweight
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3
Q

a. greater vestibular (Bartholin’s) gland
b. perineal body
c. Cowper’s gland
d. crus of clitoris
e. bulbospongiosus

A

a. greater vestibular (Bartholin’s) gland
b. perineal body
c. Cowper’s gland
d. crus of clitoris
e. bulbospongiosus

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4
Q

This photograph is of a new born with hydrocele. This occurs as a result of

a. patent processus vaginalis
b. cryptorchidism
c. androgen insufficiency
d. ectopic testes
e. patent ductus arteriosus

A

This photograph is of a new born with hydrocele. This occurs as a result of

a. patent processus vaginalis
b. cryptorchidism
c. androgen insufficiency
d. ectopic testes
e. patent ductus arteriosus

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5
Q

This girl had difficulty swallowing. The arrow indicates a/an

  1. inflamed palatine tonsil
  2. inflamed adenoid
  3. normal adenoid
  4. normal palatine tonsil
  5. inflamed uvula
  6. normal uvula
  7. inflamed appendix
A

This girl had difficulty swallowing. The arrow indicates a/an

1. inflamed palatine tonsil
2. inflamed adenoid
3. normal adenoid
4. normal palatine tonsil
5. inflamed uvula
6. normal uvula
7. inflamed appendix

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6
Q

What is structure Z?

a. yolk sac
b. polar body
c. extraembryonic mesoderm
d. amnion
e. chorionic villi

A

What is structure Z?

a. yolk sac
b. polar body
c. extraembryonic mesoderm
d. amnion
e. chorionic villi

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7
Q

This diagram is the anterior view of the cervix and uterus. The supports of the cervix indicated are

  1. cardinal ligaments
  2. levator ani muscle
  3. round ligaments
  4. ovarian ligaments
A

This diagram is the anterior view of the cervix and uterus. The supports of the cervix indicated are

1. cardinal ligaments
2. levator ani muscle
3. round ligaments
4. ovarian ligaments

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8
Q

A baby was born at 27/40. She was given three doses of surfactant and ventilated. On day 4, a chest x-ray showed ‘solid’ lungs. The photomicrograph shows

  1. hyaline membrane disease
  2. normal lung for this age
  3. pneumonia
  4. pneumothorax
  5. pneumopericardium
  6. intraventricular haemmorhage
A

A baby was born at 27/40. She was given three doses of surfactant and ventilated. On day 4, a chest x-ray showed ‘solid’ lungs. The photomicrograph shows

1. hyaline membrane disease
2. normal lung for this age
3. pneumonia
4. pneumothorax
5. pneumopericardium
6. intraventricular haemmorhage

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9
Q

This diagram shows the inguinal canal of a 3-week old baby. What abnormality is shown?

  1. Hydrocoele
  2. Complete inguinal hernia
  3. Ectopic testis
  4. Intra-abdominal testis
  5. Teratoma
A

This diagram shows the inguinal canal of a 3-week old baby. What abnormality is shown?

  1. Hydrocoele
    2. Complete inguinal hernia
  2. Ectopic testis
  3. Intra-abdominal testis
  4. Teratoma
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10
Q

A 2-year-old girl is vomiting, refuses to eat and has a fever. She has a non-blanching haemorhagic rash. She is up to date with all her vaccinations. Which infective agent is
most likely to be associated with her condition?

  1. Haemophilus influenza
  2. Herpes simplex virus
  3. Mycobacterium tuberculosis
  4. Neisseria meningitides
  5. Streptococcus pyogenes
A

A 2-year-old girl is vomiting, refuses to eat and has a fever. She has a non-blanching haemorhagic rash. She is up to date with all her vaccinations. Which infective agent is
most likely to be associated with her condition?

  1. Haemophilus influenza
  2. Herpes simplex virus
  3. Mycobacterium tuberculosis
    4. Neisseria meningitides
  4. Streptococcus pyogenes
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11
Q

The photo shows

  1. syringomyelia
  2. exomphalos
  3. Meckel-Gruber syndrome
  4. sirenomelia
  5. amniotic band disruption
  6. gastroschisis
A

The photo shows

  1. syringomyelia
    2. exomphalos
  2. Meckel-Gruber syndrome
  3. sirenomelia
  4. amniotic band disruption
  5. gastroschisis
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12
Q

The photo shows

  1. syringomyelia
  2. exomphalos
  3. Meckel-Gruber syndrome
  4. sirenomelia
  5. amniotic band disruption
  6. gastroschisis
A

The photo shows

  1. syringomyelia
  2. exomphalos
  3. Meckel-Gruber syndrome
  4. sirenomelia
  5. amniotic band disruption
    6. gastroschisis
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13
Q

The photomicrograph shows

  1. normal prostate
  2. prostatic adenocarcinoma
  3. normal testis
  4. papillary serous tumour of the testis
  5. transitional cell carcinoma
A

The photomicrograph shows

1. normal prostate
2. prostatic adenocarcinoma
3. normal testis
4. papillary serous tumour of the testis
5. transitional cell carcinoma

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14
Q

A 24 year old man presented to his GP complaining of a lump in the right testis. The patient was referred to his local urology department and underwent a right orchidectomy. In
this histopathology specimen of the tissue, the arrow indicates

  1. seminomatous tumour cells
  2. non-seminomatous tumour cells
  3. lymphocytes
  4. papillary serous carcinoma
  5. Sertoli cell tumour cells
A

A 24 year old man presented to his GP complaining of a lump in the right testis. The patient was referred to his local urology department and underwent a right orchidectomy. In
this histopathology specimen of the tissue, the arrow indicates

1. seminomatous tumour cells
2. non-seminomatous tumour cells
3. lymphocytes
4. papillary serous carcinoma
5. Sertoli cell tumour cells

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15
Q

State each type of testicular cancer shown [3]

A

The large images show a general histology pattern of a seminoma (upper panel)

**undifferentiated embryonal carcinoma (middle panel) **

teratoma: a tumor displaying differentiation into various somatic tissues (bottom panel).

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16
Q

This ovarian tumour is a/an

  1. adenocarcinoma
  2. teratoma
  3. dysgerminoma
  4. granulosa cell tumour
  5. choriocarcinoma
  6. seminoma
A

This ovarian tumour is a/an

  1. adenocarcinoma
  2. teratoma
  3. dysgerminoma
  4. granulosa cell tumour
  5. choriocarcinoma
  6. seminoma
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17
Q
  1. Human papilloma virus
  2. Herpes simplex virus
  3. Tricomonas vaginalis
  4. Neisseria gonorrhoea
  5. Chlamydia trachomatis
A

1. Human papilloma virus
2. Herpes simplex virus
3. Tricomonas vaginalis
4. Neisseria gonorrhoea
5. Chlamydia trachomatis

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18
Q

A caudal epidural would
1. anaesthetise the lower pelvic viscera, but would leave the legs unaffected.
2. anaesthetise the lower pelvic viscera and the legs.
3. anaesthetise the pudendal nerve.
4. anaesthetise just the perineum and the lower quarter of the vagina.
5. anaesthetise the area below the waist

A

A caudal epidural would
1. anaesthetise the lower pelvic viscera, but would leave the legs unaffected.
2. anaesthetise the lower pelvic viscera and the legs.
3. anaesthetise the pudendal nerve.
4. anaesthetise just the perineum and the lower quarter of the vagina.
5. anaesthetise the area below the waist

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19
Q
A
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20
Q

What is the most likely syndrome that this baby has?

A. Amniotic band syndrome

B. Angelman syndrome

C. Down syndrome

D.Edwards syndrome

E. Prader-Willi syndrome

A

What is the most likely syndrome that this baby has?

A. Amniotic band syndrome

B. Angelman syndrome

C. Down syndrome

D.Edwards syndrome

E. Prader-Willi syndrome

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21
Q

What structure is A pointing to in this photomicrograph of an ovary?

A Corpus albicans

B. Corpus luteum

C. Primordial follicle

D. Primary follicle

E. Oocyte

A

What structure is A pointing to in this photomicrograph of an ovary?

A Corpus albicans

B. Corpus luteum

C. Primordial follicle

D. Primary follicle

E. Oocyte

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22
Q

What is the blue arrow pointing at?

A. posterior vaginal fornix

B. broad ligament

C. rectouterine pouch (of Douglas)

D. rectovesical pouch

E. vesicouterine

A

What is the blue arrow pointing at?

A. posterior vaginal fornix

B. broad ligament

C. rectouterine pouch (of Douglas)

D. rectovesical pouch

E. vesicouterine

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23
Q

The arrow is pointing to what structure in the breast?

A Lactiferous sinus
B. Lactiferous duct
C. Areola
D. Smooth muscle cells
E. Suspensory ligament

A

The arrow is pointing to what structure in the breast?

A Lactiferous sinus
B. Lactiferous duct
C. Areola
D. Smooth muscle cells
E. Suspensory ligament

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24
Q

This diagram shows the changes that occur after fertilisation and before implantation.
Name structure (e).

A. zygote
B. morula
C.blastocyst
D. embryo
E. fetus

A

This diagram shows the changes that occur after fertilisation and before implantation.
Name structure (e).

A. zygote
B. morula
C.blastocyst
D. embryo
E. fetus

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25
A baby who is described as small for gestational age is one whose weight at birth falls below which centile for their gestational age? A. 3rd centile B. 15th centile C. 10th centile D. 5th centile E. 20th centile
A baby who is described as small for gestational age is one whose weight at birth falls below which centile for their gestational age? A. 3rd centile B. 15th centile **C. 10th centile** D. 5th centile E. 20th centile
26
What structure is labelled A in this photomicrograph of seminiferous tubules? A. Primary spermatocytes B. Secondary spermatocytes C. Spermatogonia D. Spermatids E. Spermatozoa
What structure is labelled A in this photomicrograph of seminiferous tubules? A. Primary spermatocytes B. Secondary spermatocytes C. Spermatogonia D. Spermatids **E. Spermatozoa**
27
What cells do you see in this photomicrograph of a cervical smear? A. Chondrocytes B. Epithelial cells C. Fibroblasts D. Lymphocytes E. Myocytes
What cells do you see in this photomicrograph of a cervical smear? A. Chondrocytes **B. Epithelial cells** C. Fibroblasts D. Lymphocytes E. Myocytes
28
What hormone is responsible for stimulating uterine contractions, production of placental prostaglandin A. Gonadotrophin-releasing hormone B. Luteinising hormone C.Oxytocin D. Prolactin E. Progesterone
What hormone is responsible for stimulating uterine contractions, production of placental prostaglandin A. Gonadotrophin-releasing hormone B. Luteinising hormone **C.Oxytocin** D. Prolactin E. Progesterone
29
What is structure X? A. Corpus luteum B. Primary oocyte C. Secondary oocyte D.Graafian follicle E. Corpus albicans
What is structure X? A. Corpus luteum B. Primary oocyte C. Secondary oocyte **D.Graafian follicle** E. Corpus albicans
30
What is the most likely syndrome that images in this photograph suggest? A. Amniotic band syndrome B. Angelman syndrome C. Down syndrome D. Edwards syndrome E. Prader- Willi syndrome
What is the most likely syndrome that images in this photograph suggest? A. **Amniotic band syndrome** B. Angelman syndrome C. Down syndrome D. Edwards syndrome E. Prader- Willi syndrome
31
What is the congenital heart defect shown in this diagram? A. Critical pulmonary stenosis B. Coarctation of the aorta C. Pulmonary valve atresia D. Ventricular septal defect E. Tetralogy of Fallot
What is the congenital heart defect shown in this diagram? A. Critical pulmonary stenosis B. Coarctation of the aorta C. Pulmonary valve atresia D. Ventricular septal defect **E. Tetralogy of Fallot**
32
Identify this neural tube defect. A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
Identify this neural tube defect. A. Encephalocoele B. Meningocoele C. Spina bifida occulta **D. Myelomeningocoele** E. Anencephaly
33
Identify this neural tube defect. A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
Identify this neural tube defect. A. Encephalocoele **B. Meningocoele ** C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
34
Identify this neural tube defect. A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
Identify this neural tube defect. **A. Encephalocoele** B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
35
In this photograph of a baby with meningococcus septicaemia what is the most likely cause? A. Haemophilus influenzae B.Neisseria meningitidis C. Pseudomonas sp. D. Staphylococcus sp. E. Streptococcus pneumoniae
In this photograph of a baby with meningococcus septicaemia what is the most likely cause? A. Haemophilus influenzae **B.Neisseria meningitidis** C. Pseudomonas sp. D. Staphylococcus sp. E. Streptococcus pneumoniae
36
The diagram shows a sagital section of an embryo at about day 16. Idnetify A A. definative yolk sac B. extraembryonic mesoderm C. chorionic cavity D. hypobalst 0% E. amniotic cavity
The diagram shows a sagital section of an embryo at about day 16. Idnetify A **A. definative yolk sac** B. extraembryonic mesoderm C. chorionic cavity D. hypobalst 0% E. amniotic cavity
37
What type of follicle is labelled A in this photomicrograph of an ovary? A. Antral B. Graafian C. Primary D. Primordial E. Secondary (Growing)
What type of follicle is labelled A in this photomicrograph of an ovary? A. Antral B. Graafian C. Primary **D. Primordial ** E. Secondary (Growing)
38
What structure in this photomicrograph of the male reproductive system is labelled A? A. Ductus (vas) deferens B. Epididymis C. Penis D. Prostate gland E. Seminiferous tubules
A. Ductus (vas) deferens **B. Epididymis** C. Penis D. Prostate gland E. Seminiferous tubules
39
These graphs show hormonal changes throughout the menstrual cycle. In pregnancy, which hormone maintains the corpus luteum and the production of hormone A until the placenta produces hormone A. A. Oestradiol B. Human chorionic gonadotrophin C. Progesterone D. Insulin-like growth factor E. Gonadotrophin- releasing hormone
These graphs show hormonal changes throughout the menstrual cycle. In pregnancy, which hormone maintains the corpus luteum and the production of hormone A until the placenta produces hormone A. A. Oestradiol **B. Human chorionic gonadotrophin** C. Progesterone D. Insulin-like growth factor E. Gonadotrophin- releasing hormone
40
This picture shows brain calcification in an infant. What is the most likely condition? A. Chronic renal failure B. Toxoplasmosis C. Congenital cytomegalovirus D. Intracerebral haemorrhage E. Cavernous angioma
A. Chronic renal failure B. Toxoplasmosis **C. Congenital cytomegalovirus** D. Intracerebral haemorrhage E. Cavernous angioma
41
From what cells of the ovary did this tumour originate? A. Epithelial cells B. Germ cells C. Sex cord stromal cells D. Smooth muscle cells E. Mixture of A, B and C
From what cells of the ovary did this tumour originate? A. Epithelial cells **B. Germ cells** C. Sex cord stromal cells D. Smooth muscle cells E. Mixture of A, B and C
42
This graph shows hormonal changes throughout pregnancy. Hormone C is measured as part of the 1st and 2nd trimester screening tests for Down's syndrome. What is hormone C? gonadotrophin- releasing hormone Insulin-like growth factor Progesterone human chorionic gonadotrophin Oestradiol
This graph shows hormonal changes throughout pregnancy. Hormone C is measured as part of the 1st and 2nd trimester screening tests for Down's syndrome. What is hormone C? gonadotrophin- releasing hormone Insulin-like growth factor Progesterone **human chorionic gonadotrophin** Oestradiol
43
On the diagram of the female perineum, identify A A. Cowper's gland B. perineal body C. crura of clitoris D. Bartholin's gland E. bulb of vestibule
On the diagram of the female perineum, identify A A. Cowper's gland B. perineal body C. crura of clitoris D. **Bartholin's gland** E. bulb of vestibule
44
The definition of antepartum haemorrhage is? 1. significant bleeding from the birth canal after the 24th week of pregnancy 2. significant bleeding from the birth canal after 32nd week of pregnancy 3. significant bleeding from the birth canal before the 24th week of pregnancy
The definition of antepartum haemorrhage is? **1. significant bleeding from the birth canal after the 24th week of pregnancy** 2. significant bleeding from the birth canal after 32nd week of pregnancy 3. significant bleeding from the birth canal before the 24th week of pregnancy
45
Which of the following is not a pre-requisite for the use of these obstetric instruments? 1. The greatest diameter of the fetal head must have passed the pelvic brim 2. The cervix must be fully dilated 3. The membranes must have ruptured 4. The bladder must be empty 5. The patient must have adequate analgesia 6. The pregnancy must be 37+ weeks
Which of the following is not a pre-requisite for the use of these obstetric instruments? 1. The greatest diameter of the fetal head must have passed the pelvic brim 2. The cervix must be fully dilated 3. The membranes must have ruptured 4. The bladder must be empty 5. The patient must have adequate analgesia **6. The pregnancy must be 37+ weeks**
46
Which of the following is not a risk factor for intrauterine growth retardation? 1. Pre-eclampsia 2. Congenital abnormalities 3. Infections 4. Placental insufficiency 5. First pregnancy
Which of the following is not a risk factor for intrauterine growth retardation? 1. Pre-eclampsia 2. Congenital abnormalities 3. Infections 4. Placental insufficiency **5. First pregnancy**
47
Dizygotic twinning is more likely to occur....... 1. in younger women 2. as a result of fertility treatments 3. parity <5 4. by chance
Dizygotic twinning is more likely to occur....... 1. in younger women **2. as a result of fertility treatments** 3. parity <5 4. by chance
48
The puerperium is the period which...... 1. Begins with the delivery of the baby and ends 6 weeks later 2. Begins with the delivery of the placenta and ends 6 weeks later 3. Begins with the delivery of the baby and ends 6 months later
The puerperium is the period which...... 1. Begins with the delivery of the baby and ends 6 weeks later **2. Begins with the delivery of the placenta and ends 6 weeks later** 3. Begins with the delivery of the baby and ends 6 months later
49
This is not a cause of recurrent miscarriage........... 1. autoimmune disease 2. chromosomal abnormalities 3. endometriosis 4. cervical incompetence 5. infection 6. hormonal disturbances
This is not a cause of recurrent miscarriage........... 1. autoimmune disease 2. chromosomal abnormalities **3. endometriosis** 4. cervical incompetence 5. infection 6. hormonal disturbances
50
Light & painless PV bleeding with a closed cervical os & the uterus is size expected from dates is termed..... 1. A threatened miscarriage 2. A complete miscarriage 3. A missed miscarriage 4. Ongoing miscarriage
Light & painless PV bleeding with a closed cervical os & the uterus is size expected from dates is termed..... 1. **A threatened miscarriage** 2. A complete miscarriage 3. A missed miscarriage 4. Ongoing miscarriage
51
What is the potential impact on the unborn fetus of Toxoplasma gondii? 1. Stillbirth 2. Premature delivery 3. physical damage,eg eye disorders 4. Neurological disorders leading to learning difficulties 5. None of the above 6. All of the above
**6. All of the above**
52
Administration of live vaccines (such as MMR) is often delayed until after one year of age. Which of the following factors may interfere with live vaccines in babies under 6 months of age? 1. Lactoferrin in breastmilk 2. Immunoglobulin G acquired before birth 3. Neutrophil immaturity 4. Absence of an adjuvant in the vaccine 5. Immunological naivety
Administration of live vaccines (such as MMR) is often delayed until after one year of age. Which of the following factors may interfere with live vaccines in babies under 6 months of age? 1. Lactoferrin in breastmilk **2. Immunoglobulin G acquired before birth** 3. Neutrophil immaturity 4. Absence of an adjuvant in the vaccine 5. Immunological naivety
53
Which of the following factors are most important in preventing collapse of aerated alveoli in the newborn baby? 1. The first gasp 2. Hepatic glycogen 3. Pulmonary surfactant 4. Closure of the ductus arteriosus 5. Bradykinin
Which of the following factors are most important in preventing collapse of aerated alveoli in the newborn baby? 1. The first gasp 2. Hepatic glycogen **3. Pulmonary surfactant** 4. Closure of the ductus arteriosus 5. Bradykinin
54
The 5 components of the Apgar score are: 1. Colour, respiratory effort, muscle tone, reflex irritability, heart rate 2. Appearance, breathing rate, grimace, pulse, activity 3. complexion, respiration, floppiness, cry, pulse rate
The 5 components of the Apgar score are: **1. Colour, respiratory effort, muscle tone, reflex irritability, heart rate** 2. Appearance, breathing rate, grimace, pulse, activity 3. complexion, respiration, floppiness, cry, pulse rate
55
Common neonatal problems: Which of the following is a cause of jaundice in the first 24 hours of life? 1. Hepatitis B 2. Biliary atresia 3. Physiological jaundice 4. ABO immune haemolysis 5. Breastmilk jaundice
**4. ABO immune haemolysis**
56
Problems of prematurity: Respiratory Distress Syndrome (RDS) is caused by: 1. Lack of brown fat 2. Surfactant deficiency 3. Lack of alveolar development 4. Pulmonary hypoplasia 5. High surface area-to- volume ratio
Problems of prematurity: Respiratory Distress Syndrome (RDS) is caused by: 1. Lack of brown fat **2. Surfactant deficiency** 3. Lack of alveolar development 4. Pulmonary hypoplasia 5. High surface area-to- volume ratio
57
This lesion, found on the lower back of a newborn baby, arises from abnormal development of which embryonic structure(s)? 1. Frontonasal process 2. Endoderm 3. Angiogenic cells 4. Yolk sac 5. Neural folds
This lesion, found on the lower back of a newborn baby, arises from abnormal development of which embryonic structure(s)? 1. Frontonasal process 2. Endoderm 3. Angiogenic cells 4. Yolk sac **5. Neural folds**
58
Congenital Heart Disease: Which of the following is not a feature of Tetralogy of Fallot? 1. Atrial septal defect 2. Pulmonary stenosis 3. Right ventricular hypertrophy 4. Ventricular septal defect 5. Over-riding aorta
Congenital Heart Disease: Which of the following is not a feature of Tetralogy of Fallot? **1. Atrial septal defect** 2. Pulmonary stenosis 3. Right ventricular hypertrophy 4. Ventricular septal defect 5. Over-riding aorta
59
Select the statement below which best describes Low Birth Weight (LBW) babies 3. 1. All premature babies are LBW 2. Conditions related to immaturity are the leading cause of neonatal death in the UK 3. 8% of births in Yemen are Low Birth Weight 4. In the UK, LBW babies have the same survival as normal birth weight babies 5. If a baby is small-for-gestational age they will also be LBW
1. All premature babies are LBW **2. Conditions related to immaturity are the leading cause of neonatal death in the UK** 3. 8% of births in Yemen are Low Birth Weight 4. In the UK, LBW babies have the same survival as normal birth weight babies 5. If a baby is small-for-gestational age they will also be LBW
60
Which congenital infection causes fetal anaemia, heart failure and hydrops fetalis? 1. Rubella 2. Cytomegalovirus 3. Toxoplasmosis 4. Parvovirus B19 5. Varicella
Which congenital infection causes fetal anaemia, heart failure and hydrops fetalis? 1. Rubella 2. Cytomegalovirus 3. Toxoplasmosis **4. Parvovirus B19** 5. Varicella
61
Genetic disease in childhood: A polymorphic genetic marker is: 1. Responsible for a number of different inherited diseases 2. Gives rise to several alternative phenotypes 3. Present at a frequency of >1% in the normal population 4. A series of linked alleles 5. A genetic tag that is unique to a particular person
Genetic disease in childhood: A polymorphic genetic marker is: 1. Responsible for a number of different inherited diseases 2. Gives rise to several alternative phenotypes **Present at a frequency of >1% in the normal population** 4. A series of linked alleles 5. A genetic tag that is unique to a particular person
62
Developmental delay and disability: Which of the following will be most helpful for a pre-school child with uncomplicated learning disabilities? 1. Physiotherapy 2. Portage service 3. Acute Paediatrician 4. Intensive care unit 5. The AA
Developmental delay and disability: Which of the following will be most helpful for a pre-school child with uncomplicated learning disabilities? 1. Physiotherapy **2. Portage service** 3. Acute Paediatrician 4. Intensive care unit 5. The AA
63
Which of the following statements about wheezing in infancy is incorrect? 1. It is mainly triggered by viral infections 2. The wheeze occurs in the expiratory phase of respiration 3. Most children with wheezing in infancy will develop allergic asthma in later life 4. Maternal smoking is a risk factor for wheezing in infancy 5. The airways tend to narrow during the expiratory phase of respiration
Which of the following statements about wheezing in infancy is incorrect? 1. It is mainly triggered by viral infections 2. The wheeze occurs in the expiratory phase of respiration **3. Most children with wheezing in infancy will develop allergic asthma in later life** 4. Maternal smoking is a risk factor for wheezing in infancy 5. The airways tend to narrow during the expiratory phase of respiration
64
Child Psychiatry: which of the following is a feature of autism? 1. Impaired communication 2. Bed wetting 3. Criminal behaviour 4. Hallucinations 5. Truancy
Child Psychiatry: which of the following is a feature of autism? **1. Impaired communication** 2. Bed wetting 3. Criminal behaviour 4. Hallucinations 5. Truancy
65
Childhood infections: This 4-year old boy has a fever and a vesicular rash. What is the most likely cause? 1. Smallpox 2. Measles 3. Meningococcal disease 4. Tuberculosis 5. Chickenpox
Childhood infections: This 4-year old boy has a fever and a vesicular rash. What is the most likely cause? 1. Smallpox 2. Measles 3. Meningococcal disease 4. Tuberculosis **5. Chickenpox**
66
Malignant disease in children: Which of the following malignancies is not seen in childhood: 1. Retinoblastoma 2. Teratoma 3. Wilm’s tumour 4. Bronchial carcinoma 5. Acute leukemia
Malignant disease in children: Which of the following malignancies is not seen in childhood: 1. Retinoblastoma 2. Teratoma 3. Wilm’s tumour **4. Bronchial carcinoma** 5. Acute leukemia
67
The majority of patients referred with short stature have the following..... 1. Constitutional growth delay 2. Endocrine disorders 3. Chronic diseases 4. Psychosocial deprivation 5. Dysmorphic syndromes 6. Variation of normal growth
The majority of patients referred with short stature have the following..... 1. Constitutional growth delay 2. Endocrine disorders 3. Chronic diseases 4. Psychosocial deprivation 5. Dysmorphic syndromes **6. Variation of normal growth**
68
Red circle is 1. pterion 2. inion 3. asterion 4. nasion 5. glabella
**pterion**
69
A indicates 1. transition zone of the prostate gland 2. peripheral zone of the prostate gland 3. central zone of the prostate gland 4. seminal vescicle 5. bladder
A indicates 1. transition zone of the prostate gland **2. peripheral zone of the prostate gland** 3. central zone of the prostate gland 4. seminal vescicle 5. bladder
70
A baby was born at 27/40. She was given three doses doses of surfactant and ventilated. On day 4, a chest x-ray showed 'solid' lungs. The photomicrograph shows 1. hyaline membrane disease 2. normal lung for this age 3. pneumonia 4. pneumothorax 5. pneumopericardium 6. intraventricular haemmorhage
**1. hyaline membrane disease**
71
Characteristics depicted suggest 1. Kleinfelter syndrome 2. Cushing syndrome 3. Turner syndrome 4. Acromegaly 5. Congenital adrenal hyperplasia
Characteristics depicted suggest **1. Kleinfelter syndrome** 2. Cushing syndrome 3. Turner syndrome 4. Acromegaly 5. Congenital adrenal hyperplasia
72
This diagram shows the inguinal canal of a 3-week old baby. What abnormality is shown? 1. Hydrocoele 2. Complete inguinal hernia 3. Ectopic testis 4. Intra-abdominal testis 5. Teratoma
2. Complete inguinal hernia
73
A 2-year-old girl is vomiting, refuses to eat and has a fever. She has a non-blanching haemorhagic rash. She is up to date with all her vaccinations. Which infective agent is most likely to be associated with her condition? 1. Haemophilus influenza 2. Herpes simplex virus 3. Mycobacterium tuberculosis 4. Neisseria meningitides 5. Streptococcus pyogenes
A 2-year-old girl is vomiting, refuses to eat and has a fever. She has a non-blanching haemorhagic rash. She is up to date with all her vaccinations. Which infective agent is most likely to be associated with her condition? 1. Haemophilus influenza 2. Herpes simplex virus 3. Mycobacterium tuberculosis **4. Neisseria meningitides** 5. Streptococcus pyogenes
74
This is the nose of a newborn baby. This appearance is characteristic of: 1. staphylococcal infection 2. acne 3. eczema 4. milia 5. erythema toxicum
4. milia
75
The photo shows 1. syringomyelia 2. exomphalos 3. Meckel-Gruber syndrome 4. sirenomelia 5. amniotic band disruption 6. gastroschisis
The photo shows 1. syringomyelia **2. exomphalos** 3. Meckel-Gruber syndrome 4. sirenomelia 5. amniotic band disruption 6. gastroschisis
76
A 24 year old man presented to his GP complaining of a lump in the right testis. The patient was referred to his local urology department and underwent a right orchidectomy. In this histopathology specimen of the tissue, the arrow indicates 1. seminomatous tumour cells 2. non-seminomatous tumour cells 3. lymphocytes 4. papillary serous carcinoma 5. Sertoli cell tumour cells
A 24 year old man presented to his GP complaining of a lump in the right testis. The patient was referred to his local urology department and underwent a right orchidectomy. In this histopathology specimen of the tissue, the arrow indicates **1. seminomatous tumour cells** 2. non-seminomatous tumour cells 3. lymphocytes 4. papillary serous carcinoma 5. Sertoli cell tumour cells
77
A represents a. ischial tuberosity b. ischial spine c. ramus of ischium d. pubic tubercle e. pubis
A represents **a. ischial tuberosity** b. ischial spine c. ramus of ischium d. pubic tubercle e. pubis
78
What is the most likely syndrome that this baby has? A. Amniotic band syndrome B. Angelman syndrome C. Down syndrome D. Edwards syndrome E. Prader- Willi syndrome
What is the most likely syndrome that this baby has? A. Amniotic band syndrome B. Angelman syndrome C. Down syndrome **D. Edwards syndrome** E. Prader- Willi syndrome
79
A. Corpus albicans B. Corpus luteum C. Primordial follicle D. Primary follicle E. Oocyte
**A. Corpus albicans**
80
A. posterior vaginal fornix B. broad ligament C. rectouterine pouch (of Douglas) D. rectovesical pouch E. vesicouterine
**C. rectouterine pouch (of Douglas)**
81
Name structure (e). A. zygote B. morula C. blastocyst D. embryo E. fetus
**C. blastocyst**
82
A. bladder B. posterior fornix C. vaginal canal D. cervix E. fundus ofuterus
A. bladder B. posterior fornix C. vaginal canal **D. cervix** E. fundus ofuterus
83
What structure is labelled A in this photomicrograph of seminiferous tubules? A. Primary spermatocytes B. Secondary spermatocytes C. Spermatogonia D. Spermatids E. Spermatozoa
What structure is labelled A in this photomicrograph of seminiferous tubules? A. Primary spermatocytes B. Secondary spermatocytes C. Spermatogonia D. Spermatids **E. Spermatozoa**
84
What hormone is responsible for stimulating uterine contractions, production of placental prostaglandin and is missing in this diagram? A. Gonadotrophin-releasing hormone B. Luteinising hormone C. Oxytocin D. Prolactin E. Progesterone
What hormone is responsible for stimulating uterine contractions, production of placental prostaglandin and is missing in this diagram? A. Gonadotrophin-releasing hormone B. Luteinising hormone **C. Oxytocin** D. Prolactin E. Progesterone
85
A. Corpus luteum B. Primary oocyte C. Secondary oocyte D. Graafian follicle E. Corpus albicans
A. Corpus luteum B. Primary oocyte C. Secondary oocyte **D. Graafian follicle** E. Corpus albicans
86
A. Amniotic band syndrome B. Angelman syndrome C. Down syndrome D. Edwards syndrome E. Prader- Willi syndrome
**A. Amniotic band syndrome** B. Angelman syndrome C. Down syndrome D. Edwards syndrome E. Prader- Willi syndrome
87
A. obturator internus B. coccygeus C. levator ani D. piriformis E. illiacus
A. obturator internus B. coccygeus **C. levator ani** D. piriformis E. illiacus
88
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele B. Meningocoele C. Spina bifida occulta **D. Myelomeningocoele** E. Anencephaly
89
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele B. Meningocoele C. Spina bifida occulta **D. Myelomeningocoele** E. Anencephaly
90
A. definative yolk sac B. extraembryonic mesoderm C. chorionic cavity D. hypobalst E. amniotic cavity
**A. definative yolk sac** B. extraembryonic mesoderm C. chorionic cavity D. hypobalst E. amniotic cavity
91
These graphs show hormonal changes throughout the menstrual cycle. In pregnancy, which hormone maintains the corpus luteum and the production of hormone A until the placenta produces hormone A. A. Oestradiol B. Human chorionic gonadotrophin C. Progesterone D. Insulin-like growth factor E. Gonadotrophin-releasing hormone
These graphs show hormonal changes throughout the menstrual cycle. In pregnancy, which hormone maintains the corpus luteum and the production of hormone A until the placenta produces hormone A. A. Oestradiol **B. Human chorionic gonadotrophin** C. Progesterone D. Insulin-like growth factor E. Gonadotrophin-releasing hormone
92
This picture shows brain calcification in an infant. What is the most likely condition? A. Chronic renal failure B. Toxoplasmosis C.Congenital cytomegalovirus D. Intracerebral haemorrhage E. Cavernous angioma
This picture shows brain calcification in an infant. What is the most likely condition? A. Chronic renal failure B. Toxoplasmosis **C.Congenital cytomegalovirus** D. Intracerebral haemorrhage E. Cavernous angioma
93
This graph shows hormonal changes throughout pregnancy. Hormone C is measured as part of the 1st and 2nd trimester screening tests for Down's syndrome. What is hormone C? A. Oestradiol B. Human chorionic gonadotrophin C. Progesterone D. Insulin-like growth factor E. Gonadotrophin-releasing hormone
This graph shows hormonal changes throughout pregnancy. Hormone C is measured as part of the 1st and 2nd trimester screening tests for Down's syndrome. What is hormone C? A. Oestradiol **B. Human chorionic gonadotrophin** C. Progesterone D. Insulin-like growth factor E. Gonadotrophin-releasing hormone
94
This picture shows one of the major causes of death in a pre-term baby. What is this condition? Waterhouse-Friderichsen syndrome Meningitis Periventricular haemorrhage Hyaline membrane disease Neonatal sepsis
This picture shows one of the major causes of death in a pre-term baby. What is this condition? Waterhouse-Friderichsen syndrome Meningitis **Periventricular haemorrhage** Hyaline membrane disease Neonatal sepsis
95
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
**E. Anencephaly**
96
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele B. Meningocoele C. Spina bifida occulta **D. Myelomeningocoele** E. Anencephaly
97
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele B. Meningocoele **C. Spina bifida occulta** D. Myelomeningocoele E. Anencephaly
98
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele B. Meningocoele C. Spina bifida occulta **D. Myelomeningocoele** E. Anencephaly
99
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele **B. Meningocoele** C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
100
Red circle is 1. pterion 2. inion 3. asterion 4. nasion 5. glabella
**pterion**
101
A indicates 1. transition zone of the prostate gland 2. peripheral zone of the prostate gland 3. central zone of the prostate gland 4. seminal vescicle 5. bladder
A indicates 1. transition zone of the prostate gland **2. peripheral zone of the prostate gland** 3. central zone of the prostate gland 4. seminal vescicle 5. bladder
102
A baby was born at 27/40. She was given three doses doses of surfactant and ventilated. On day 4, a chest x-ray showed 'solid' lungs. The photomicrograph shows 1. hyaline membrane disease 2. normal lung for this age 3. pneumonia 4. pneumothorax 5. pneumopericardium 6. intraventricular haemmorhage
**1. hyaline membrane disease**
103
Characteristics depicted suggest 1. Kleinfelter syndrome 2. Cushing syndrome 3. Turner syndrome 4. Acromegaly 5. Congenital adrenal hyperplasia
Characteristics depicted suggest **1. Kleinfelter syndrome** 2. Cushing syndrome 3. Turner syndrome 4. Acromegaly 5. Congenital adrenal hyperplasia
104
This diagram shows the inguinal canal of a 3-week old baby. What abnormality is shown? 1. Hydrocoele 2. Complete inguinal hernia 3. Ectopic testis 4. Intra-abdominal testis 5. Teratoma
2. Complete inguinal hernia
105
A 2-year-old girl is vomiting, refuses to eat and has a fever. She has a non-blanching haemorhagic rash. She is up to date with all her vaccinations. Which infective agent is most likely to be associated with her condition? 1. Haemophilus influenza 2. Herpes simplex virus 3. Mycobacterium tuberculosis 4. Neisseria meningitides 5. Streptococcus pyogenes
A 2-year-old girl is vomiting, refuses to eat and has a fever. She has a non-blanching haemorhagic rash. She is up to date with all her vaccinations. Which infective agent is most likely to be associated with her condition? 1. Haemophilus influenza 2. Herpes simplex virus 3. Mycobacterium tuberculosis **4. Neisseria meningitides** 5. Streptococcus pyogenes
106
This is the nose of a newborn baby. This appearance is characteristic of: 1. staphylococcal infection 2. acne 3. eczema 4. milia 5. erythema toxicum
4. milia
107
The photo shows 1. syringomyelia 2. exomphalos 3. Meckel-Gruber syndrome 4. sirenomelia 5. amniotic band disruption 6. gastroschisis
The photo shows 1. syringomyelia **2. exomphalos** 3. Meckel-Gruber syndrome 4. sirenomelia 5. amniotic band disruption 6. gastroschisis
108
A 24 year old man presented to his GP complaining of a lump in the right testis. The patient was referred to his local urology department and underwent a right orchidectomy. In this histopathology specimen of the tissue, the arrow indicates 1. seminomatous tumour cells 2. non-seminomatous tumour cells 3. lymphocytes 4. papillary serous carcinoma 5. Sertoli cell tumour cells
A 24 year old man presented to his GP complaining of a lump in the right testis. The patient was referred to his local urology department and underwent a right orchidectomy. In this histopathology specimen of the tissue, the arrow indicates **1. seminomatous tumour cells** 2. non-seminomatous tumour cells 3. lymphocytes 4. papillary serous carcinoma 5. Sertoli cell tumour cells
109
A represents a. ischial tuberosity b. ischial spine c. ramus of ischium d. pubic tubercle e. pubis
A represents **a. ischial tuberosity** b. ischial spine c. ramus of ischium d. pubic tubercle e. pubis
110
What is the most likely syndrome that this baby has? A. Amniotic band syndrome B. Angelman syndrome C. Down syndrome D. Edwards syndrome E. Prader- Willi syndrome
What is the most likely syndrome that this baby has? A. Amniotic band syndrome B. Angelman syndrome C. Down syndrome **D. Edwards syndrome** E. Prader- Willi syndrome
111
A. Corpus albicans B. Corpus luteum C. Primordial follicle D. Primary follicle E. Oocyte
**A. Corpus albicans**
112
A. posterior vaginal fornix B. broad ligament C. rectouterine pouch (of Douglas) D. rectovesical pouch E. vesicouterine
**C. rectouterine pouch (of Douglas)**
113
Name structure (e). A. zygote B. morula C. blastocyst D. embryo E. fetus
**C. blastocyst**
114
A. bladder B. posterior fornix C. vaginal canal D. cervix E. fundus ofuterus
A. bladder B. posterior fornix C. vaginal canal **D. cervix** E. fundus ofuterus
115
What structure is labelled A in this photomicrograph of seminiferous tubules? A. Primary spermatocytes B. Secondary spermatocytes C. Spermatogonia D. Spermatids E. Spermatozoa
What structure is labelled A in this photomicrograph of seminiferous tubules? A. Primary spermatocytes B. Secondary spermatocytes C. Spermatogonia D. Spermatids **E. Spermatozoa**
116
What hormone is responsible for stimulating uterine contractions, production of placental prostaglandin and is missing in this diagram? A. Gonadotrophin-releasing hormone B. Luteinising hormone C. Oxytocin D. Prolactin E. Progesterone
What hormone is responsible for stimulating uterine contractions, production of placental prostaglandin and is missing in this diagram? A. Gonadotrophin-releasing hormone B. Luteinising hormone **C. Oxytocin** D. Prolactin E. Progesterone
117
A. Corpus luteum B. Primary oocyte C. Secondary oocyte D. Graafian follicle E. Corpus albicans
A. Corpus luteum B. Primary oocyte C. Secondary oocyte **D. Graafian follicle** E. Corpus albicans
118
A. Amniotic band syndrome B. Angelman syndrome C. Down syndrome D. Edwards syndrome E. Prader- Willi syndrome
**A. Amniotic band syndrome** B. Angelman syndrome C. Down syndrome D. Edwards syndrome E. Prader- Willi syndrome
119
A. obturator internus B. coccygeus C. levator ani D. piriformis E. illiacus
A. obturator internus B. coccygeus **C. levator ani** D. piriformis E. illiacus
120
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele B. Meningocoele C. Spina bifida occulta **D. Myelomeningocoele** E. Anencephaly
121
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele B. Meningocoele C. Spina bifida occulta **D. Myelomeningocoele** E. Anencephaly
122
A. definative yolk sac B. extraembryonic mesoderm C. chorionic cavity D. hypobalst E. amniotic cavity
**A. definative yolk sac** B. extraembryonic mesoderm C. chorionic cavity D. hypobalst E. amniotic cavity
123
These graphs show hormonal changes throughout the menstrual cycle. In pregnancy, which hormone maintains the corpus luteum and the production of hormone A until the placenta produces hormone A. A. Oestradiol B. Human chorionic gonadotrophin C. Progesterone D. Insulin-like growth factor E. Gonadotrophin-releasing hormone
These graphs show hormonal changes throughout the menstrual cycle. In pregnancy, which hormone maintains the corpus luteum and the production of hormone A until the placenta produces hormone A. A. Oestradiol **B. Human chorionic gonadotrophin** C. Progesterone D. Insulin-like growth factor E. Gonadotrophin-releasing hormone
124
This picture shows brain calcification in an infant. What is the most likely condition? A. Chronic renal failure B. Toxoplasmosis C.Congenital cytomegalovirus D. Intracerebral haemorrhage E. Cavernous angioma
This picture shows brain calcification in an infant. What is the most likely condition? A. Chronic renal failure B. Toxoplasmosis **C.Congenital cytomegalovirus** D. Intracerebral haemorrhage E. Cavernous angioma
125
This graph shows hormonal changes throughout pregnancy. Hormone C is measured as part of the 1st and 2nd trimester screening tests for Down's syndrome. What is hormone C? A. Oestradiol B. Human chorionic gonadotrophin C. Progesterone D. Insulin-like growth factor E. Gonadotrophin-releasing hormone
This graph shows hormonal changes throughout pregnancy. Hormone C is measured as part of the 1st and 2nd trimester screening tests for Down's syndrome. What is hormone C? A. Oestradiol **B. Human chorionic gonadotrophin** C. Progesterone D. Insulin-like growth factor E. Gonadotrophin-releasing hormone
126
This picture shows one of the major causes of death in a pre-term baby. What is this condition? Waterhouse-Friderichsen syndrome Meningitis Periventricular haemorrhage Hyaline membrane disease Neonatal sepsis
This picture shows one of the major causes of death in a pre-term baby. What is this condition? Waterhouse-Friderichsen syndrome Meningitis **Periventricular haemorrhage** Hyaline membrane disease Neonatal sepsis
127
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
**E. Anencephaly**
128
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele B. Meningocoele C. Spina bifida occulta **D. Myelomeningocoele** E. Anencephaly
129
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele B. Meningocoele **C. Spina bifida occulta** D. Myelomeningocoele E. Anencephaly
130
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele B. Meningocoele C. Spina bifida occulta **D. Myelomeningocoele** E. Anencephaly
131
A. Encephalocoele B. Meningocoele C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
A. Encephalocoele **B. Meningocoele** C. Spina bifida occulta D. Myelomeningocoele E. Anencephaly
132
A 30 year old women is pregnant with her 3rd baby. She is now 31+2 weeks. She was concerned that the fetus seemed to have decreased movement and was referred for a umbilical cord and MCA Doppler. (she had an umbilical cord and MCA Doppler at the same stage of gestation for one of her previous pregnancies the normal umbilical cord Doppler is shown at the top). Her present umbilical cord Doppler is shown at the bottom. **Explain the blood flow pattern seen in the normal ultrasound**
At the **end of the diastolic filling of the atria**, there is **still flow going through the umbilical cord**; so there is still depth to it. Flow **never stops flowing** all the way through **even if the fetal heart stops beating** !
133
A 30 year old women is pregnant with her 3rd baby. She is now 31+2 weeks. She was concerned that the fetus seemed to have decreased movement and was referred for a umbilical cord and MCA Doppler. (she had an umbilical cord and MCA Doppler at the same stage of gestation for one of her previous pregnancies the normal umbilical cord Doppler is shown at the top). Her present umbilical cord Doppler is shown at the bottom. **What is the pattern shown in the present Doppler and what could be the consequence of this flow pattern?** [2]
**Absent flow** throughout the **diastole phase**; blood is **only flowing through systole** **IUGR**
134
A 30 year old women is pregnant with her 3rd baby. She is now 31+2 weeks. She was concerned that the fetus seemed to have decreased movement and was referred for a umbilical cord and MCA Doppler. (she had an umbilical cord and MCA Doppler at the same stage of gestation for one of her previous pregnancies the normal umbilical cord Doppler is shown at the top). Her present umbilical cord Doppler is shown at the bottom. **Explain why the pattern shown in the present Doppler is occurring** [2]
(Absent flow in diastole) as blood is bein diverted to the MCA; vasoconstriction of the umbilical cord vessels is occuring
135
A 30 year old women is pregnant with her 3rd baby. She is now 31+2 weeks. She was concerned that the fetus seemed to have decreased movement and was referred for a umbilical cord and MCA Doppler. (she had an umbilical cord and MCA Doppler at the same stage of gestation for one of her previous pregnancies the **normal MCA Doppler is shown at the top**). **Her present MCA is shown at the bottom**. What specific type of IUGR is shown here if you compare the umbilical cord and the MCA? Explain how you can tell form the diagram
Asymmetric IUGR with brain sparing **There is no low point in the diastole phase in the MCA** (due to vasodilation)
136
A baby is born by spontaneous vaginal delivery at 34 weeks to a mother who had tested positive for Covid-19. The baby boy weighed 2,065g. The neonate was admitted to the NICU, he was breathing room air without tachypnea and was started on feeds of expressed milk supplemented with formulae when breast milk was not available. 15 hrs after delivery they developed tachypnea and at 20 hrs they developed a fever, at 25 hrs they developed feed intolerance. An x-ray was taken at 30 hrs and repeated at 36 hrs. They tested positive for Covid-19 at 48 hrs after delivery. What is the most likely diagnosis?
**Necrotizing** **enterocolitis**
137
Necrotising fasciitis in children may follow [] infection Varicella-zoster infection Herpes simplex virus Cytomegalovirus T. gondii HIV
Necrotising fasciitis in children may follow [] infection **Varicella-zoster infection** Herpes simplex virus Cytomegalovirus T. gondii HIV
138
Necrotising fasciitis in children may be caused by infection from which pathogen, aftern an initial infection from VZV? [1]
Group A streptococcus (GAS): e.g. Streptococcus pyogenes
139
140
This picture is from an autopsy. What is the pathology? exomphalos omphalocele necrotising enterocolitis peritonitits
This picture is from an autopsy. What is the pathology? exomphalos omphalocele **necrotising enterocolitis** peritonitits
141
An 8 year old child presents to her local A&E department with a 5 day history of progressively worsening fever, cough, nasal congestion and conjunctivitis. A rash started to appear on their face the day before. On examination of the oral mucosa small white spots are observed opposite the 1st and 2nd molars. Their vaccination status is unknown. What is the most likely diagnosis? Covid 19 Measles Mumps Rubella Streptococcal scarlet fever
An 8 year old child presents to her local A&E department with a 5 day history of progressively worsening fever, cough, nasal congestion and conjunctivitis. A rash started to appear on their face the day before. **On examination of the oral mucosa small white spots are observed opposite the 1st and 2nd molars.** Their vaccination status is unknown. What is the most likely diagnosis? Covid 19 **Measles** Mumps Rubella Streptococcal scarlet fever
142
An 7 year old boy is referred to an educational psychologist by the school because of concerns over their impaired communication development. During the assessment this behaviour is noted What is the most likely diagnosis? Attention deficit hyperactivity disorder Autistic spectrum disorder Conduct disorder Obsessive compulsive disorder Schizophrenia
**Autistic spectrum disorder**: Not playing ‘pretend’ games (e.g. feeding a doll with play food) Not smiling back when you smile at them Not playing social games like ‘peek-a-boo’ Being over-sensitive or reacting strangely to some tastes, smells or sounds Not pointing at interesting objects or looking when you point Being very late starting to ‘babble’ and talk, not talking as much as other children or being able to say fewer than ten words at age 2 years old Repetitive movements, for example rocking their body, flicking their fingers or hand-flapping Repeating the same phrases over and over.
143
An individual is diagnosed with attention deficit hyperactivity disorder. When reviewing the mothers antenatal history what would be the most likely behaviour or condition that the mother had during her pregnancy? Continued to drink alcohol Continued to smoke Had gestational diabetes Had pre-eclampsia Was obese
An individual is diagnosed with attention deficit hyperactivity disorder. When reviewing the mothers antenatal history what would be the most likely behaviour or condition that the mother had during her pregnancy? Continued to drink alcohol **Continued to smoke** Had gestational diabetes Had pre-eclampsia Was obese
144
A female child was diagnosed with Turner syndrome at age of 4 years. She was given oxandrolone and her height was within target height. She was referred for further assessment at 7 year 10 months because of vaginal bleeding. On assessment she was assessed as Tanner stage 3. How would this be best managed? Counselling Do nothing Give GnRH analogues Give growth hormone Stop oxandrolone
A female child was diagnosed with Turner syndrome at age of 4 years. She was given oxandrolone and her height was within target height. She was referred for further assessment at 7 year 10 months because of vaginal bleeding. On assessment she was assessed as Tanner stage 3. How would this be best managed? **Counselling** Do nothing Give GnRH analogues - can't do this because stage 3. Give growth hormone Stop oxandrolone
145
A baby is born at 36 weeks Their length and weight are assessed at 8 weeks when they have their 1st set of vaccinations. What is their gestationally corrected age?
40 weeks - 36 weeks = **4 weeks preterm** Start the plot at plotted at **4 week not 8 weeks**
146
A 75 year old man has an open prostatectomy because of longstanding urinary problems that have not been managed by medication. What is the most likely diagnosis? Benign prostate hyperplasia Embryonal carcinoma Prostate cancer Prostatis Testicular cancer
A 75 year old man has an open prostatectomy because of longstanding urinary problems that have not been managed by medication. What is the most likely diagnosis? **Benign prostate hyperplasia** Embryonal carcinoma Prostate cancer Prostatis Testicular cancer
147
A 75 year old man has an open prostatectomy because of longstanding urinary problems that have not been managed by medication. What is the most likely diagnosis? Benign prostate hyperplasia Embryonal carcinoma Prostate cancer Prostatis Testicular cancer
A 75 year old man has an open prostatectomy because of longstanding urinary problems that have not been managed by medication. What is the most likely diagnosis? Benign prostate hyperplasia Embryonal carcinoma **Prostate cancer** Prostatis Testicular cancer
148
A 20 year old male goes to their GP concerned that their left testis / scrotum looks like a bag of worms. What anatomical issue means that the left side is predominately at risk? There are no valves on the left side The pampiniform plexus is more complex on the left The left testicular vein is longer and drains to left renal vein at a right angle The left testicular vein is shorter and drains into the IVC Left renal has a longer course to reach the IVC
A 20 year old male goes to their GP concerned that their left testis / scrotum looks like a bag of worms. What anatomical issue means that the left side is predominately at risk? There are no valves on the left side The pampiniform plexus is more complex on the left **The left testicular vein is longer and drains to left renal vein at a right angle** The left testicular vein is shorter and drains into the IVC Left renal has a longer course to reach the IVC
149
This 30 year old male has both a direct and indirect inguinal hernia. What structure is the yellow arrow pointing to? Superficial ring Deep ring Hesselbach’s triangle Linea alba Aponeurosis of internal, external oblique and transversus abdominis muscles
This 30 year old male has both a direct and indirect inguinal hernia. What structure is the yellow arrow pointing to? Superficial ring **Deep ring** Hesselbach’s triangle Linea alba Aponeurosis of internal, external oblique and transversus abdominis muscles
150
Which structure in this image helps you determine if a hernia is direct or indirect? [1]
Inferior epigastric vessels
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Label A-C
A: Vas deferens B: IEV C: gonadal vessels
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Is the hernia labelled at A a direct or indirect hernia?
Indirect
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Which of the following is the vas deferens? A B C D E
Which of the following is the vas deferens? A B C **D** E
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Which of the following is the inferior epigastric vessels? A B C D E
Which of the following is the inferior epigastric vessels? A **B** C D E
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Which of the following is the gonadal vessels? A B C D E
Which of the following is the gonodal vessels? A B C D **E**
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Is this a direct or indirect hernia?
Indirect
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A 30 year old woman has a routine PAP smear and on investigation the pathologist notes these large glassy inclusions. What infectious pathogen is most likely to have caused these? Chlamydia trachomatis Neisseria gonorrhoeae Herpes simplex virus type I Human papilloma virus type 16 Treponema pallidum
**Chlamydia trachomatis**
158
Which of the following is leiomyoma, leiomyosarcoma and normal?
A: **normal** B: **fibroids** C: a **malignant leiomyosarcoma** is hypercellular and less fascicular, and consists of **atypical smooth-muscle cells with hyperchromatic, enlarged nuclei**. Increased mitotic figures and necrosis are frequent histological findings in leiomyosarcomas
159
A 30 year old woman has a routine PAP smear and on investigation the pathologist notes these abnormalities. What infectious pathogen is most likely to have caused these? Chlamydia trachomatis Neisseria gonorrhoeae Herpes simplex virus type I Human papilloma virus type 16 Treponema pallidum
A 30 year old woman has a routine PAP smear and on investigation the pathologist notes these abnormalities. What infectious pathogen is most likely to have caused these? Chlamydia trachomatis **Neisseria gonorrhoeae** Herpes simplex virus type I Human papilloma virus type 16 Treponema pallidum
160
A 30 year old woman has a routine PAP smear and on investigation the pathologist isolates the pathogen. What is the most likely pathogen? [1]
A 30 year old woman has a routine PAP smear and on investigation the pathologist isolates the pathogen. What is the most likely pathogen? **syphilis**
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During a routine ultrasound the image below was generated the largest depth of amniotic fluid was measured at 10 cm? What is this condition called? Oligohydramnios Normal amniotic volume Polyhydramnios
During a routine ultrasound the image below was generated the largest depth of amniotic fluid was measured at 10 cm? What is this condition called? Oligohydramnios Normal amniotic volume **Polyhydramnios**
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A mother gives birth to a baby with chorioretintitis, hydrocephalus and intracranial atherosclerosis. A biopsy of the mothers muscle is shown below. What is the causative pathogen? Toxoplasma gondii Treponema pallidum Parvovirus B19 Chlamydia trachomatis Neisseria gonorrhoeae
A mother gives birth to a baby with chorioretintitis, hydrocephalus and intracranial atherosclerosis. A biopsy of the mothers muscle is shown below. What is the causative pathogen? **Toxoplasma gondii** Treponema pallidum Parvovirus B19 Chlamydia trachomatis Neisseria gonorrhoeae
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A mother gives birth to a baby who lafter a couple of weeks looks like this. What is he infected with? Toxoplasma gondii Treponema pallidum Parvovirus B19 Chlamydia trachomatis Neisseria gonorrhoeae
Parvovirus B19: slapped cheeks
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At the routine 24 week antenatal visit the BP is measured at 142/92mmHg for the second time after the 1st reading was also 145/95mmHg 4 hrs previously. There is protein detected in her urine as well. What is the most likely diagnosis? Gestational diabetes Placental abruption Placental praevia Pre-eclampsia Chronic hypertension of pregnancy
At the routine 24 week antenatal visit the BP is measured at 142/92mmHg for the second time after the 1st reading was also 145/95mmHg 4 hrs previously. There is protein detected in her urine as well. What is the most likely diagnosis? Gestational diabetes Placental abruption Placental praevia **Pre-eclampsia** Chronic hypertension of pregnancy
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At the routine 18 week antenatal visit the BP is measured at 142/92mmHg for the second time after the 1st reading was also 145/95mmHg 4 hrs previously. There is protein detected in her urine as well. What is the most likely diagnosis? Gestational diabetes Placental abruption Placental praevia Pre-eclampsia Chronic hypertension of pregnancy
At the routine 18 week antenatal visit the BP is measured at 142/92mmHg for the second time after the 1st reading was also 145/95mmHg 4 hrs previously. There is protein detected in her urine as well. What is the most likely diagnosis? Gestational diabetes Placental abruption Placental praevia Pre-eclampsia **Chronic hypertension of pregnancy**: up to week 20
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An ultrasound is taken at 28 weeks showing the head (H) of the fetus is engaged with the internal os (white arrow). The red Doppler shows the umbilical vessels. What is the name of this issue? Placenta previa Placental abruption Vasa previa Placenta increta Placenta accreta
**Vasa previa** - **umbilical vessels** connecting the **placenta** to the baby are **covering the internal os**
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A 27 year old in her 3rd pregnancy is having a routine ultrasound which is shown below. The uterus is to the left hand side of the image and the bladder is at the bottom of the image. What is the problem shown? Complete molar pregnancy Incompetent cervix Placental abruption Placenta previa Vasa praevia
**Placenta previa**: The US shows that the placenta is covering the OS opening completely
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This is an ultrasound from a 16 week pregnant woman with heavy vaginal bleeding on examination the cervical os is dilated. The arrows are indicating the significant detachment of the placenta with hemorrahge. What is the type of miscarriage shown? Complete Incomplete Inevitable Missed Threatened
**Inevitable** The arrows are pointing to bleeding between the sac and the uterine wall. From the symptoms reported this would be inevitable miscarriage. The difference to a threatened miscarriage is that the cervical os is open compared to closed in a threatened
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What is the aroow pointing at urethra vagina rectum ureter anal canal
**urethra**
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These images show a childhood respiratory condition. They show congenital lobar emphysema a bronchogenic cyst asthma pneumonia tuberculosis
**congenital lobar emphysema**
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Corpus luteum
172
what is the principal venous drainage of the anal cancl above the line indicated here? superior rectal vein to internal iliac vein middle rectal vein to inferior mesenteric vein middle rectal ven to internal iliac vein superior rectal vein to inferior mesenteric vein inferior rectal vein to inferior mesenteric vein
superior rectal vein to inferior mesenteric vein
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Which nerve loops around the ligament highlight here? [1]
pudendal nerve
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The inguinal ligament runs from the ASIS to the pubic tubercle. What structure is located at its mid-point? [1]
**femoral artery**
175
The structure highlighted in this cross section of the prostate gland serves what function? passage of ejaculant from seminal vesciles and vas deferens entrance of prostatic fluid into urethra vestigal / remnant uterus prevent retrograde ejaculation opening of bulbourethral glands
The structure highlighted in this cross section of the prostate gland serves what function? passage of ejaculant from seminal vesciles and vas deferens entrance of prostatic fluid into urethra **vestigal / remnant uterus** prevent retrograde ejaculation opening of bulbourethral glands
176
A collection of striated muscle fibres are highlighted in this picture of the testes and spermatic cord. From which abdominal layer are these fibres derived? external obliique internal oblique transversalis fascia transversalis abdominus parietal peritoneum
A collection of striated muscle fibres are highlighted in this picture of the testes and spermatic cord. From which abdominal layer are these fibres derived? external obliique **internal oblique** transversalis fascia transversalis abdominus parietal peritoneum
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The left testicular artery is hihglighted here. From where is this vessel derived abdominal aorta T12 external iliac internal iliac abdominal aorta L2 pudendal artery
The left testicular artery is hihglighted here. From where is this vessel derived abdominal aorta T12 external iliac internal iliac **abdominal aorta L2** pudendal artery
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what is A? [1]
**obturator artery**
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What is A iliacus obturator internus obturator externus leavtor ani coccygeus
What is A **iliacus** obturator internus obturator externus leavtor ani coccygeus
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A nine month old girl died after a sudden illness. Her adrenal gland is shown in her photograph. What most likekly caused her illness? reye's syndrome meningoccocal septicaemia neonate herpes virus infection congenital adrenal hyperplasia
A nine month old girl died after a sudden illness. Her adrenal gland is shown in her photograph. What most likekly caused her illness? reye's syndrome **meningoccocal septicaemia** neonate herpes virus infection congenital adrenal hyperplasia
181
The prostate gland has zones that are associated with higher prevalence of different conditions. Choose the option for the zone indicated by the arrow the condition most commonly associated with this zone transitional zone - benign prostatc hyperplasia peripheral zone - prostate cancer transitional zone - prostate cancer peripheral zone - benign prostatc hyperplasia
The prostate gland has zones that are associated with higher prevalence of different conditions. Choose the option for the zone indicated by the arrow the condition most commonly associated with this zone **transitional zone - benign prostatc hyperplasia** peripheral zone - prostate cancer transitional zone - prostate cancer peripheral zone - benign prostatc hyperplasia
182
The prostate gland has zones that are associated with higher prevalence of different conditions. Choose the option for the zone indicated by the arrow the condition most commonly associated with this zone transitional zone - benign prostatc hyperplasia peripheral zone - prostate cancer transitional zone - prostate cancer peripheral zone - benign prostatc hyperplasia
The prostate gland has zones that are associated with higher prevalence of different conditions. Choose the option for the zone indicated by the arrow the condition most commonly associated with this zone transitional zone - benign prostatc hyperplasia **peripheral zone - prostate cancer** transitional zone - prostate cancer peripheral zone - benign prostatc hyperplasia
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adenocarcinoma of the prostate, Gleeson Grade 5 adenocarcinoma of the prostate, Gleeson Grade 1 transitional cell carcinoma BPE stratified squamous carcinoma
**adenocarcinoma of the prostate, Gleeson Grade 5**
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dysgerminoma serous adenocarcinoma mucinous adenocarcnoma teratoma granulosa cell tumour
**dysgerminoma** serous adenocarcinoma mucinous adenocarcnoma teratoma granulosa cell tumour
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leimyosarcoma leimyoma fibroadenoma adenocarcinoma of the breast normal breast tissue fibrosarcoma
leimyosarcoma leimyoma fibroadenoma **adenocarcinoma of the breast** normal breast tissue fibrosarcoma
186
Name a cause of encephalitis that is reverisble with acyclovir [1]
Herpes Simplex Virus
187
Depicted is a brain abscess. Which is the most common cause of bacterial caused brain abscess? Streptococcus agalactiae Streptococcus mutans Streptococcus pneumoniae Neisseria meningitidis Staphylococcus aureus
Staphylococcus aureus
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In the UK, the most common cause of bacterial meningitis is infection with Streptococcus agalactiae Streptococcus mutans Streptococcus pneumoniae Neisseria meningitidis Staphylococcus aureus
In the UK, the most common cause of bacterial meningitis is infection with Streptococcus agalactiae Streptococcus mutans Streptococcus pneumoniae **Neisseria meningitidis** Staphylococcus aureus
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Meningococcal bacteria are divided into distinct serogroups, according to their polysaccharide outer capsule. The most common serogroups that cause disease worldwide are groups B, C, A, Y and W. However, the number of cases caused by serogroup [] has significantly reduced in the UK since routine vaccination was introduced in 1999 in those age groups targeted for vaccination meningococcal group B (MenB) meningococcal group C (MenC) meningococcal group A (MenA) meningococcal group Y (MenY) meningococcal group W (MenW)
**meningococcal group C (MenC)**
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Which serotype of meningococcal disease accounts for the vast majority of meningococcal disease in the UK? meningococcal group B (MenB) meningococcal group C (MenC) meningococcal group A (MenA) meningococcal group Y (MenY) meningococcal group W (MenW)
**meningococcal group B (MenB)**