CR2 Drugs Flashcards

Question

How would you manange an acute TIA?

Answer 1

300mg aspirin

Answer 2

Treatment: **prostaglandin inhibitor,** such as **ibuprofen**; **surgery**

Answer 3

Always follow yourlocal area guidelines. These are developed by looking at the bacteria in the local area for theirantibiotic resistanceso are specific to that population. CRB Score 0: **Amoxicillin or Doxycycline or Clathromycin** CRB Score 1-2: **Amoxicillin** AND **Clathromycin** OR **Doxycycline** CRB Score 3-4: **Benzylpenicillin**

Answer 4

ACE inhibitors AT II receptor antagonists

Answer 5

A Offer ACE inhibitor or Angiotensin receptor blockers (ARBs) if have: type 2 diabetes under 55 but not black African / African-Caribbean OR Offer calcium-channel blocker (CCB) who: aged 55 or over AND no type 2 diabetes black African / African-Caribbean

Answer 6

If on ACE inhibitor: **- Add CCB or thiazide-like diuretic [2]** If on CCB: **- Add ACE inhibitor or ARB or thiazide-like diuretic**

Answer 7

**Dobutamine** Verapamil Diltiazem Amlodipine Clopidogrel

Answer 8

**Sympathomimetic β1 agonist** which is used in cardiac stress test and imaging **Increases contractility not rate**

Answer 9

**99m-technetium**

Answer 10

Isosorbide mono/dinitrate

Answer 11

Which of the following acts as a nitrate and also opens potassium channels which hyperpolarises the cell and prevents opening of voltage gated calcium channels so net effect is vasodilation. **Nicorandil** Amlodipine Nifedipine Verapamil Diltiazem

Answer 12

Aten**olol** Propran**olol**

Answer 13

Beta blocker **causes down regulation of RAAS** as well as acting as a anti-sympathomimetic

Answer 14

Which of the following calcium channel blockers are selective for voltage gated calcium channels in myocardium to reduce HR and O2 demand Dobutamine **Verapamil** Diltiazem Amlodipine Clopidogrel

Answer 15

Which of the following calcium channel blockers act on both myocardium and vessels for dual effect Dobutamine Verapamil **Diltiazem** Amlodipine Clopidogrel

Answer 16

Which of the following calcium channel blockers are selective for voltage gated calcium channels in **blood vessels** to cause vasodilation and decrease TPR. Dobutamine Verapamil Diltiazem **Amlodipine** **Nifedipine**

Answer 17

**Aspirin**

Answer 18

Clopidogrel

Answer 19

Fava beans, primaquine, cotrimoxazole, dapsone

Answer 20

**Anticoagulant** **Vit K** antagonist Acts agaisnt **factors II, VII, IX, X** AND **protein C &/ S**

Answer 21

Which of the following an heparin antagonist Fondaparinux Warfarin **Protamine** Folate *Binds heparin to inactivate it. Does not work as well on LMWH*

Answer 22

Which of the following is used in treatment of VTE / DVT and PE and is a has high selectivity for just anti-Xa activity and little antithrombin activity. **Fondaparinux** Warfarin Protamine Folate

Answer 23

LMWH Anti-Xa effect

Answer 24

Heparin induced thrombocytopaenia(HIT) 5-14 days after start(rare) bleeding

Answer 25

Which of the following blocks the Na/K/2Cl symporter in the ascending loop of Henle? Chlorthalidone Bendroflumethiazide **Furosemide** Spironolactone

Answer 26

Hypokalaemia

Answer 27

Which of the following blocks the Na/Cl symporter in the distal convoluted tubule to prevent sodium reabsorption? Chlorthalidone **Bendroflumethiazide** Furosemide Spironolactone

Answer 28

Capto**pril**, lisino**pril**

Answer 29

Whoch of the following blocks angiotensin II receptor preventing its vasoconstrictive effects? lisinopril Captopril Spironolactone **Losartan** Amiloride

Answer 30

Whoch of the following blocks aldosterone transporter? lisinopril Captopril **Spironolactone** Losartan Amiloride

Answer 31

Which of the following may you prescribe alongside spironlactone to normalise potassium levels? lisinopril Captopril **Furosemide** Losartan Amiloride

Answer 32

Which of the following blocks epithelial sodium channels(ENaC) in the late DCT, collecting tubules and collecting ducts inhibiting sodium reabsorption there lisinopril Captopril Furosemide Losartan **Amiloride**

Answer 33

Which of the following is an antihypertensive alpha 2 agonist that causes a decrease in CO and vascular tone? **Clonidine** Carvedilol Propranolol atenolol doxazosin

Answer 34

Which of the following is an alpha 1 antagonist that causes a decrease in CO and vascular tone? Clonidine Carvedilol Propranolol atenolol **doxazosin** **and prazosin**

Answer 35

Which of the following is a β2 agonist that causes short acting smooth muscle relaxation in the bronchioles Salmeterol Beclomethasone **Salbutamol** Prednisolone Indaceterol

Answer 36

Which of the following is a β2 agonist that causes long acting smooth muscle relaxation (LABA) in the bronchioles [2] **Salmeterol** Beclomethasone Salbutamol Prednisolone **Indaceterol**

Answer 37

Which of the following acts on steroid receptor to modify nuclear expression, in this case it prevents inflammatory expression for asthma / COPD treatment? Salmeterol Beclomethasone Salbutamol **Prednisolone** Indaceterol

Answer 38

Asthma treatments is a corticosteroid? Salmeterol **Beclomethasone** Salbutamol **Prednisolone** Indaceterol

Answer 39

Which of the following is associated with Cushings syndrome in long term use? Salmeterol Beclomethasone Salbutamol **Prednisolone** Indaceterol

Answer 40

Which of the following is associated with Cushings syndrome in long term use? Salmeterol Beclomethasone Salbutamol **Prednisolone** Indaceterol

Answer 41

Which of the following is a corticosteroid used to treat asthma but acts locally upon inhalation? Salmeterol **Beclomethasone** Salbutamol Prednisolone Indaceterol

Answer 42

Which of the following is a SAMA used in asthma / COPD control? Tiotropium **Ipratropium** Montelukast Theophylline Beclomethasone

Answer 43

Which of the following treatments for TB blocks causes mycoloic acid synthesis Rifampicin **Isoniazid** Pyrazinamide **Ethambutol**

Answer 44

Which of the following stains bodily secretions orange **Rifampicin** Isoniazid Pyrazinamide Ethambutol

Answer 45

Which of the following blocks bacterial RNA polymerase for the treatment of TB **Rifampicin** Isoniazid Pyrazinamide Ethambutol

Answer 46

Which of the following is a prodrug which is converted to pyrazinoic acid and disrupts the membrane potential in TB causing death Rifampicin Isoniazid **Pyrazinamide** Ethambutol

Answer 47

You are attending a cardiology clinic one afternoon. A 56-year-old man presents for a medication review. He is currently taking a beta-blocker but is still frequently symptomatic. From his medication history, it is evident that he does not tolerate calcium channel blockers. The consultant considers the option of starting him on a new drug called nicorandil. Strangely enough, the patient feels that nicorandil is a calcium channel blocker and is not keen to try it out. You have been asked to explain the mechanism of the new drug to this patient. What is the mechanism through which the new drug exerts its effect? Causes vasoconstriction by activating guanylyl cyclase which causes an increase in cGMP Causes vasodilation by inactivating ATP-sensitive potassium channels Causes vasodilation by increasing intracellular calcium load **Causes vasodilation by activating guanylyl cyclase which causes an increase in cGMP** Causes vasodilation by inhibiting guanylyl cyclase which causes an increase in cGMP

Answer 48

A 65-year-old lady attends the GP surgery for a routine hypertension review. She has been taking amlodipine for a year and although her blood pressure is well controlled her ankles often become swollen. The ankle swelling is worse at the end of the day since starting amlodipine. The GP decides to prescribe a diuretic instead of amlodipine. Which of the following diuretics acts on the sodium-chloride transporter of the distal tubule? Acetazolamide (carbonic anhydrase inhibitor) **Bendroflumethiazide (thiazide diuretic)** Furosemide (loop diuretic) Spironolactone (potassium-sparing diuretic) Mannitol (osmotic diuretic)

Answer 49

A 71-year-old gentleman is admitted to the renal ward with acute kidney injury after having diarrhoea and vomiting for 4 days. Blood tests show that his potassium is below normal limits. You note that this is likely due to his gastrointestinal symptoms. You check his medications to ensure nothing is making the situation worse. You find that he is on diuretic therapy for the treatment of heart failure. Which of the following diuretics is associated with hypokalaemia? Triamterene **Bumetanide** Amiloride Spironolactone Eplerenone Loop diuretics may cause hypokalaemia

Answer 50

A 55-year-old man is admitted to the emergency department with sudden onset chest pain. His ECG shows ST depression in leads II, III, & aVF. His troponin is also found to be raised. He is treated for an NSTEMI (non-ST-elevation myocardial infarction), and as part of this treatment regime, he is given ticagrelor. What is the mechanism of action of this drug? Activates antithrombin III which mainly inhibits factors Xa and IIa **Inhibits ADP binding to platelet receptors** Inhibits prothrombinase complex-bound and clot-associated factor Xa Inhibits the production of prostaglandins Inhibits vitamin K epoxide reductase complex 1 Ticagrelor has a similar mechanism of action to clopidogrel - inhibits ADP binding to platelet receptors

Answer 51

A 45-year-old female is found to have a blood pressure of 185/102mmHg following ambulatory blood pressure monitoring. She is started on the ACE inhibitor Ramipril. What is the most common side effect of this drug? **A dry cough** Oedema Shortness of breath Excessive urine output Headaches

Answer 52

You are a medical student in general practice. A 67-year-old female attends for an annual checkup of her blood pressure. She has GTN spray at home. How does nitric oxide result in vasodilation? Directly opens K+ channels Directly opens Ca2+ channels **Activates guanylate cyclase** Inhibits the release of Bradykinin Activates cAMP

Answer 53

A baby is born at 36 weeks via an emergency cesarean section. His mother lives in a cottage up in the mountains. The baby looks healthy and is administered a dose of Vitamin K soon after birth. She is discharged the next day with a happy, healthy baby. Six weeks later, she presents to the hospital with the baby after she noticed increased work of breathing and difficulty while feeding. On auscultation of her heart, a continuous 'machinery' murmur is heard and is loudest at the left sternal edge. The cardiologist arrives at the scene and instructs that the child is given a dose of indomethacin. What is the mode of action of indomethacin? Endothelin receptor antagonist Phosphodiesterase inhibitor **Prostaglandin synthase inhibitor** Endothelin receptor agonist Adenosine receptor antagonist *Indomethacin inhibits prostaglandin synthesis in infants with patent ductus arteriosus*

Answer 54

A 74-year-old female was with urinary incontinence presents to the urogynaecology clinic. She was diagnosed with overactive bladder incontinence, and was started on pharmacological treatment which antagonises the parasympathetic pathway. Which of the following have a similar mechanism of action with the drug she was prescribed? Alfuzosin Meropenem Mirabegron **Atropine** Adenosine | Atropine is an antimuscarinic

Answer 55

Whilst in general practice, you review Susan a 48-year-old patient with hypertension. Despite taking ramipril, her blood pressure remains clinically elevated. Based on current guidelines you consider add-on therapy with a thiazide-like diuretic. Which of the following electrolyte disturbances may occur with this new treatment? Hypercalciuria Hyperkalaemia Hypermagnesemia **Hypokalaemia** Hypolipidaemia

Answer 56

A 65-year-old patient with chronic kidney disease is found to have a deficiency of antithrombin III after he presented to emergency department with left leg pain and swelling. A doppler-ultrasound scan of the leg confirms deep venous thrombosis (DVT). The patient is started on dabigatran. What is the mechanism of action of dabigatran? Activates anti-thrombin III P2Y12 inhibitor Glycoprotein IIb/IIIa inhibitor **Direct thrombin inhibitor** Direct factor X activator

Answer 57

Question 103 of 203 An 82-year-old lady with a history of heart failure presents to the general practice with a 5-day history of constipation. On further questioning, she tells you that she has been feeling weaker this week, and has been getting muscle cramps regularly On examination, there is reduced tone and hyporeflexia bilaterally in both the upper and lower limbs. You think this lady's presentation may be due to hypokalaemia. The patient takes a number of diuretics to control her heart failure. Which of the following diuretics is associated with hypokalaemia? Triamterene **Furosemide** Spironolactone Eplerenone Amiloride

Answer 58

A patient with a history of peripheral vascular disease presents to his GP with essential hypertension. Which of the following drugs may exacerbate his peripheral vascular symptoms? Ramipril **Atenolol** Spironolactone Hydrochlorothiazide Furosemide

Answer 59

A 60-year-old man presents to the emergency department complaining of sudden numbness of his right arm and right leg. On examination, he has decreased sensation and 3 out of 5 power throughout his right arm and right leg. A head CT reveals ischaemia along the area of the left middle cerebral artery. After initial management, he is deemed to be unfit to be prescribed clopidogrel and instead is prescribed aspirin and another antiplatelet that works by inhibiting phosphodiesterase. What medication was this patient likely prescribed in addition to the aspirin? **Dipyridamole** Heparin Ticagrelor Prasugrel Apixaban

Answer 60

A 63-year-old male presents to GP with mild chest pain and dyspnoea. The patient is normally fit and well with no significant medical history. He has a family history of heart disease with his dad passing away following a heart attack last year. The GP decides to do an ECG to confirm the diagnosis and suspects atrial flutter. Given the diagnosis, which of the following findings would you expect to see on an ECG? Broad complex tachycardia **Narrow complex tachycardia** Heart rate of 175/min Heart rate of 58/min Prolonged QT interval

Answer 61

A 53-year-old woman is reviewed in the hypertension clinic. Her past medical history includes depression and gout. Two months ago she was started on lisinopril for hypertension. The dose was gradually titrated up and her urea and electrolytes were monitored. Today she complains of a dry cough which has got gradually worse over the past four weeks. She describes it as being 'really annoying' and complains that it keeps her up at night. She is a non-smoker and a chest x-ray performed during an Emergency Department visit six weeks ago was normal. What is the most appropriate action with respect to her anti-hypertensive medications? Reassure her that the majority of ACE related coughs resolve within three months **Switch her to an angiotensin II receptor blocker** Switch her to bendroflumethiazide Switch her to amlodipine Explain that as the cough developed four weeks after starting treatment it is unlikely to be ACE related

Answer 62

A 53-year-old woman is reviewed in the hypertension clinic. Her past medical history includes depression and gout. Two months ago she was started on lisinopril for hypertension. The dose was gradually titrated up and her urea and electrolytes were monitored. Today she complains of a dry cough which has got gradually worse over the past four weeks. She describes it as being 'really annoying' and complains that it keeps her up at night. She is a non-smoker and a chest x-ray performed during an Emergency Department visit six weeks ago was normal. What is the most appropriate action with respect to her anti-hypertensive medications? Reassure her that the majority of ACE related coughs resolve within three months **Switch her to an angiotensin II receptor blocker** Switch her to bendroflumethiazide Switch her to amlodipine Explain that as the cough developed four weeks after starting treatment it is unlikely to be ACE related

Answer 63

A 68-year-old man has recently been discharged from hospital following a non-ST-elevation myocardial infarction (NSTEMI). He has a history of angina, hypertension and hypercholesterolaemia and was already taking aspirin, atorvastatin, bisoprolol and ramipril prior to his NSTEMI. Following his hospital discharge, he has been instructed to also take ticagrelor for the next 12 months. What is the mechanism of action of this newly-started drug? Activated factor X (Xa) inhibitor Cyclooxygenase inhibitor Direct thrombin inhibitor Glycoprotein IIb/IIIa receptor antagonist **P2Y12 receptor antagonist**

Answer 64

Immediately: Pharmalogical: **O2 & duiretic** Non Pharmalogical: **ventilation; ultrafiltration** After stabalisation: **ACE-I/ARB, beta-blocker, aldosterone inhibitor** Ongoing management: **Valve surgery; revasc; transplant**

Answer 65

Pirfenidone

Answer 66

Thalassaemia major (a+b) treatment: **Regular blood transfusion** BUT: can get Iron overload from constant blood transfusion: this happens because excess haemolysis can lead to excess free iron in blood (usually bound to ferritin in the spleen), which is oxidising

Answer 67

Medication to treat blood clots (**anti coagulants)** **Pacemaker**: control rhythm of heart **ICD**: shock heart if need to go into normal rhythm **Surgery**: remove areas of heart muscle / whole heart transport

Answer 68

Which of the following class of drug does indapamide fall into? ACE inhibitors: Angiotensin-II receptor antagonists Calcium-channel blocker **Diuretics** thiazide-like diuretic Beta-blockers

Answer 69

Which of the following class of drug does metoprolol fall into? ACE inhibitors: Angiotensin-II receptor antagonists Calcium-channel blocker Diuretics **Beta-blockers**

Answer 70

Which of the following class of drug does amlodipine fall into? ACE inhibitors: Angiotensin-II receptor antagonists **Calcium-channel blocker** Diuretics Beta-blockers

Answer 71

Which of the following class of drug does enalapril fall into? **ACE inhibitors**: Angiotensin-II receptor antagonists Calcium-channel blocker Diuretics Beta-blockers

Answer 72

Which of the following class of drug does losartan fall into? ACE inhibitors: **Angiotensin-II receptor antagonists** Calcium-channel blocker Diuretics Beta-blockers

Answer 73

Which of the following prevents the conversion of arachidonic acid to thromboxane A2 Heparin Warfarin **Aspirin** Dabigatran Edoxaban

Answer 74

Non-selective for **COX-1 and COX 2** enzymes (prevent aggregation) COX 2 inhibition **prevents arachidonic acid** conversion to **Thromboxane A2** Thus preventing Thromboxane A2 formation, **preventing platelet aggregation**.

Answer 75

Which of the following can cause thrombocytopenia **Heparin** Warfarin Aspirin Dabigatran Dipyridamole

Answer 76

Which of the following should not be used in pregnancy Heparin **Warfarin**: teratogenic Aspirin Dabigatran Dipyridamole

Answer 77

**Fondaprinux**

Answer 78

Which of the following is a non-specific phosphodiesterase inhibitor **Dipyridamole** Inhibits both adenosine deaminase and phosphodiesterase, preventing the degradation of cAMP, an inhibitor of platelet function

Answer 79

Dabigatran Rivaroxaban Apixaban Edoxaban

Answer 80

**Direct factor Xa inhibitor** (more modern version of heparin)

Answer 81

**Direct thrombin inhibitor**

Answer 82

Which of the following is not a direct factor Xa inhibitor Rivaroxaban Apixaban Edoxaban **Dabigatran**: direct thrombin inhibitor

Answer 83

Streptokinase Alteplase (tPA)

Answer 84

**Streptokinase**: Clot buster; Activates fibrinolytic pathway **Alteplase (tPA)**: Increase clot; breakdown by increasing Plasmin formation

Answer 85

Which of the following inhibits L type calcium channel **Amlodipine** Nicorandil Diatelzem Lisinopril **Verapamil**

Answer 86

Which of the following drug is for voltage gated calcium channels in myocardium to reduce HR and O2 demand? Amlodipine Nicorandil Diatelzem Lisinopril **Verapamil** - CCB

Answer 87

Which of the following is a CCB that acts on both myocardium and vessels for dual effect? Amlodipine Nicorandil **Diatelzem** Lisinopril Verapamil

Answer 88

Which of the following is a vasodilator that opens potassium channels which hyperpolarises the cell and prevents opening of voltage gated calcium channels and causes release of NO? Amlodipine **Nicorandil** Diatelzem Lisinopril Verapamil

Answer 89

Which of the following that particularly reduces peripheral vascular resistance / lowers peripheral BP? **Amlodipine** Bind to L-Type calcium channel Peripheral arterial vasodilator Reduce peripheral vascular resistance – lower BP Calcium channel antagonist (smooth + cardiac muscle)

Answer 90

**Verapamil** - CCB Inhibit L-Type calcium channel Reduce contractility and peripheral resistance Reduce heart rate by prolonging refractory period of AVN.

Answer 91

Which of the following can cause severe hypotension as an AE? **Amlodipine** Nicorandil Diatelzem Lisinopril Verapamil

Answer 92

Rosuvostatin

Answer 93

**Competitive inhibitor** of **HMG-CoA Reductase** Reduction of the **mevalonate** **pathway** **Inhibit cholesterol synthesis** **Inhibit LDL uptake, VLDL synthesis.**

Answer 94

rhabdomyolysis

Answer 95

Ramipril Lisinopril Captopril

Answer 96

Converted to **ramiprilat** **Inhibits ACE**, stop ACE-1 --> ACE-II conversion **Reduce sodium and H2O reabsorption** Reduces **peripheral vascular resistance.**

Answer 97

ACE breaks down **bradykinin**: causes **Dry COUGH**

Answer 98

**Hyperkalaemia** (Less Angiotensin II, NO aldosterone, less K secreted, less Na reabsorbed)

Answer 99

Valsartan Losartan

Answer 100

Which of the following would you prescribe if a patient has ACE-I intolerance? **Losartan** - ARB Captopril lisinopril Digoxin Ivabradine

Answer 101

Which of the following is an inotrope? Losartan Captopril lisinopril **Digoxin** increases the force of **myocardial contraction** and **reduces conductivity within the atrioventricular (AV) node.** Ivabradine

Answer 102

increases the **force of myocardial contraction** and **reduces conductivity** within the **atrioventricular (AV) node** **Stimulate Vagus Nerve**, **reduce** **circulating** **noradrenaline** = lower heart rate

Answer 103

Gynaecomastia

Answer 104

Which of the following has a risk of gynaecomastia? Losartan Captopril lisinopril **Digoxin** Ivabradine

Answer 105

Name the diuretic that works by blocking epithelial sodium channels in in the late DCT, collecting tubules and collecting ducts **Amiloride** Spironolactone Atenolol Propranolol Carvedilol

Answer 106

Both decrease HR and RAAS. Propranolol is **non-selective** Atenolol is **β1 selective**

Answer 107

Which of the following is an α2-agonist that causes a decrease in CO and vascular tone **Clonidine** Propranolol Atenolol Prazosin Doxazosin

Answer 108

Which of the following is an α2-agonist that causes a decrease in CO and vascular tone **Clonidine** Propranolol Atenolol Prazosin Doxazosin

Answer 109

Which of the following blocks α1 in vascular smooth muscle causing it to vasodilate Clonidine Propranolol Atenolol **Prazosin** **Doxazosin**

Answer 110

**Pirfenidone**: used to treat IPF

Answer 111

**Ivabradine** Hyperpolarization-activated cyclic nucleotide-gated (**HCN**) **channel blockers** **Slows heart rate**

Answer 112

What is the first line treatment for Asthma? **Salbutamol** Salmeterol Beclomethasone (Becotide) Montelukast Ipratropium

Answer 113

**trembling, particularly in the hands** nervous tension headaches suddenly noticeable heartbeats (palpitations) muscle cramps

Answer 114

Which of the following is a Long-Acting Beta-2 Agonist (LABA) Salbutamol **Salmeterol** Beclomethasone (Becotide) Montelukast Ipratropiuma

Answer 115

Which of the following is a maintenance therapy and combined with glucocorticoid for asthma treatment? Salbutamol **Salmeterol** Beclomethasone (Becotide) Montelukast Ipratropiuma

Answer 116

Which of the following is a maintenance therapy and combined with glucocorticoid for asthma treatment? Salbutamol **Salmeterol** Beclomethasone (Becotide) Montelukast Prednisolone

Answer 117

Which of the following is a corticosteroid used to treat asthma and acts more globally Salbutamol Salmeterol Beclomethasone (Becotide) Montelukast **Prednisolone**

Answer 118

Which of the following is a corticosteroid used to treat asthma and acts more locally Salbutamol Salmeterol **Beclomethasone (Becotide)** Montelukast Prednisolone

Answer 119

Which of the following is associated with Cushings disease if long term use occurs Salbutamol Salmeterol Beclomethasone (Becotide) Montelukast **Prednisolone**

Answer 120

Which of the following treatment for asthma can be associated with oral thrush? Salbutamol Salmeterol **Beclomethasone (Becotide)** Montelukast Prednisolone

Answer 121

Which of the following is a leukotriene antagonist to treat asthma? Salbutamol Salmeterol Beclomethasone (Becotide) **Montelukast** Prednisolone

Answer 122

What are the 4 drugs used to treat TB? [4] Rifampicin Isoniazid Pyrazinamide Ethambutol

Answer 123

Which of the following treats TB by blocking mycolic acid synthesis required for mycobacterial cell wall synthesis? Rifampicin **Isoniazid** Pyrazinamide Ethambutol

Answer 124

Which of the following is a prodrug which is converted to pyrazinoic acid and disrupts the membrane potential in TB causing death? Rifampicin Isoniazid **Pyrazinamide** Ethambutol

Answer 125

Which of the following blocks mycolic acid synthesis? Rifampicin Isoniazid Pyrazinamide **Ethambutol**

Answer 126

Which of the following blocks bacterial RNA polymerase to treat TB? **Rifampicin** Isoniazid Pyrazinamide Ethambutol

Answer 127

Alongside prescribing oxygen, which other drug would you give someone with acute heart failure? **diuretic** ACE-I/ARB beta-blocker aldosterone inhibitor

Answer 128

Which of the following is a leukotriene antagonist? Tiotropium Ipratropium **Montelukast** Theophylline Beclomethasone

Answer 129

Which of the following pithelial sodium channels(ENaC) in the late DCT, collecting tubules and collecting ducts inhibiting sodium reabsorption there lisinopril Captopril Furosemide Losartan **Amiloride**