Pituitary

Question 1

What lobe of the pituitary is oxytocin and Vasopressin released from

Answer 1

Posterior lobe

Question 2

What pathway does growth hormone signal through

Answer 2

Jak/stat pathway

Question 3

What pathway does LH, FSH, and TSH signal through

Answer 3

GPCR

Question 4

What does growth hormone increase the production of that cause increase in bone growth

Answer 4

Insulin like growth factor

Question 5

What does SST hormone do

Answer 5

It blocks the GHRH from stimulating the anterior pituitary gland to make Growth hormone

Question 6

Describe the structure of growth hormone

Answer 6

It is a single chain protein hormone

Question 7

Describe the structures of TH, FSH, and LH

Answer 7

They are dimeric proteins that all share common alpha chain

Question 8

What are the catabolic and anabolic effects of growth hormone

Answer 8

Catabolic effects: reduces central adiposity in lipid cells. Anabolic effects: increases lean body mass.

Question 9

How does growth hormone affects insulin

Answer 9

It reduces insulin sensitivity

Question 10

What is the recombinant form of human growth hormone(GH) called

Answer 10

Somtotropin or rhGH

Question 11

What are ocreotide and Lanreotide

Answer 11

Somatostatin analogs

Question 12

What are recombinant form of IGF-1

Answer 12

Mecasermin

Question 13

What is pegvisomant

Answer 13

GH receptor antagonist

Question 14

What are menotropins

Answer 14

Mixture of FSH and LH

Question 15

What is the recombinant form of HCG called

Answer 15

Choriogonadotropin

Question 16

What is desmopressin. Explain its affinity

Answer 16

It is a synthetic analog of vasopressin. It is 4000 times much more selective for V2 receptors than V1 which means it will have more anti diuretic effects than vasoconstriction effects

Question 17

List the counter indications for oxytocin

Answer 17

Fetal stress Abnormal fetal presentation. Cephalopelvic disproportion(the baby head is too big for the birth canal)