Pilosebaceous unit Flashcards
What are the 4 segments of the pilosebaceous unit?
keratinized follicular infundibulum
hair
sebacous gland
sebaceous duct
People who develop too much sebum have what pathology?
seborrheic dermatitis
What are some common features of Acne fulminans?
primarily occurs in men 13-16
characterized by abrupt eruption of nodular and suppurative acne with systemic manifestations
arthralgias, myalgias and HSM
lesions are inflamed and coalesce into painful and oozing friable plaques with hemorrhagic crusts
What is the occulusion triad?
acne conglobata, Hiradenitis suppurativa, and dissecting cellulitis (pilonidal cyst)
What are common features of acne mechanica?
result of mechanical and frictional obstruction of the pilosebaceous unit
often characterized by linear and geometric distribution
What are common features of Acne exoriee?
result of excoriation and manipulation
often associated with mental disorder
What drugs tend to cause drug-induced acne?
anabolic steroids, corticosteroids and lithium
What hormone tends to cause infantile acne?
DHEA
What are common retinoids?
tretinoin and adapalene
what do retinoids do?
normalizes follicular keratinization, expulsion of existing comedones and prevention of new lesions
What is BPO
a topical anti-inflammatory agent
Which of the oral antibiotics cause photosensitivity?
tetracycline, doxycycline, and isotretinoin
which of the oral antibiotics cause myalgias and arthraligias?
minocycline and isotretinoin
What is the treatment for grade 1 acne?
topical retinoids and BPO
What is the treatment for grade 2 acne?
topical retinoids, BPO and topical antibiotics