Physiology Qs Flashcards
What best describes the secondary peristalsis? 2017, 2014, 2013
- Starts at the site where food is stuck in the esophagus after a wave of primary peristalsis
- initiated after swallowing
- Starts at the site where food is stuck in the esophagus after a wave of primary peristalsis
What is the difference between the primary salivary secretion and oral saliva? 2017, 2014
- The primary secretion is hypotonic and saliva is hypertonic
- The primary secretion contains more Na+
- Saliva has less HCO3
- Both have the same composition of electrolytes
- The primary secretion contains more Na+
Which of the following factors is responsible for the copious secretions of the salivary gland? 2016, 2015
- NE and NO by sympathetic
- NE and Ach by ANS
- Ach and VIP by parasympathetic
- Ach and NE by sympathetic
- Ach and VIP by parasympathetic
What factor increases blood flow to salivary glands? 2014
- Vagal cholinergic
- Glossopharyngeal cholinergic
- Bradykinin
- Bradykinin
What increases blood supply to the salivary glands? 2013, Final 2010
- VIP & bradykinin
- VIP & Ach
- VIP & bradykinin
What causes movement of water in the salivary glands? 2013
- Active transport of Na and isotonic fluid secretion
- Paracellular Na transport and isotonic fluid secretion
- Paracellular Na transport and isotonic fluid secretion
What is the difference between the primary salivary secretion and oral saliva? Final 2013, 2010, 2008
- Saliva has less HCO3
- Both have the same composition of electrolytes
- The primary secretion contains more K+
- The primary secretion is hypotonic and saliva is hypertonic
- The primary secretion contains more K+
If primary peristalsis fails to clear the bolus, a wave of secondary peristalsis is initiated at the site of the bolus. Where does that take place? Final 2011
Esophagus
Which of the following is true regarding the effect of parasympathetic fibers on blood vessels of the salivary glands? 2011
VIP and bradykinin are vasodilators
What are intercalated duct cells responsible for? 2010, 2009
- HCO3- absorption
- Cl- secretion
- K+ absorption
- K+ secretion
- HCO3- secretion
- HCO3- secretion
What is the difference between primary secretion of saliva gland and the modified secretion? Final 2009
Tonicity
If a person swallowed repeatedly every 1-2 seconds. What will happen? Final 2009, 2009
Esophagus will only contract after the last swallow
What does the intercalated duct secrete? 2008
- Na and HCO3-
- Cl and K
- Na and HCO3-
Which of the following causes receptive relaxation of the stomach? Final 2017, 2011, 2009
- Somatostatin
- Gastrin
- Norepinephrine
- VIP
- VIP
What increases both the duration and amplitude of the stomach AP? Final 2017, 2016, 2015
- Adrenaline
- Sympathetic
- Acetylcholine
- Secretin
- Acetylcholine
High activity of fibers that secrete VIP on LES smooth muscle but vagal cholinergic fibers show no action potential. What does it indicate? 2016
- LES maintaining resting tone
- Over tightening of LES
- LES relaxation
- Absence of ANS control
- LES relaxation
A manometer is inserted into a patient’s mouth passing through the pharynx, UES, esophageal body, and LES. What are the pressure readings? 2016, Final 2015, Final 2012, 2012, 2011, 2008
- 0 → 50 → 0 → 30
- 50 → 30 → 0 → 0
- 0 → 30→ 0 → 50
- 0 → 50 → 0 → 30
Which recording of vagal inhibitory fibers (VIF) and vagal excitatory fibers (VEF) will be seen with receptive opening of the lower esophageal sphincter? Final 2015, 2012, 2011
- Both VIF and VEF action potentials are increased
- Both VIF and VEF action potentials are decreased
- Increased firing of VIF but absent firing of VEF
- Increased firing of VIF but absent firing of VEF
Retropulsion and grinding is the main movement of which organ? 2015, 2014, 2009
- Esophagus
- Stomach
- Small Intestines
- Cecum
- Ascending Colon
- Stomach
A movement that occurs in both esophagus and stomach during swallowing? Final 2014, 2011
- Peristalsis
- Receptive relaxation
- Receptive relaxation
The stomach efficiently mixes food by contracting the antrum against a closed pyloric sphincter. What is this process called? Final 2014, 2011
Retropulsion
What is responsible for receptive relaxation of both lower esophageal sphincter and stomach? 2014, 2012
- VIP
- NE
- Secretin
- Gastrin
- CCK
- Histamine
- VIP
Which of the following factors acts to decrease the amplitude and duration of slow waves of the stomach? 2014
- Secretin
- Gastrin
- Distension of the stomach
- Cholinergic fibers
- Secretin
Which point confers the first and maximal resistance during insertion of a nasogastric tube? Final 2013, Final 2011, 2010
Pharyngoesophageal junction
Which of the following happens during the receptive relaxation of the LES? Final 2013, Final 2010
- Increase in VIP and decrease in Ach
- Increase in VIP and decrease in NE
- Increase in VIP and decrease in Ach
What activates gastric secretions? 2013
Gastric distension
What keeps intragastric pressure constant during eating? Final 2012
- Increased tension and radius in the stomach
- Increased radius with constant tension
-
Where does retropulsion take place? Final 2012, Final 2011, 2009
Stomach
Which of the following factors promote gastric emptying? Final 2011, Final 2010
Gastric distension
What will constrict lower esophageal sphincter? 2010
Vagus Ach
What is responsible for the relaxation of the pyloric sphincter? 2009
VIP
Which neurotransmitter is most responsible for relaxation of the lower esophageal sphincter? 2009
Nitric Oxide
What best describes the slow waves of the intestinal smooth muscle cells? 2017
- Tonic contractions
- Action potentials
- Originate from interstitial cells of cajal
- Same frequency in all the gut
- Originate from interstitial cells of cajal
What is the main plexus for coordinated contraction of the gastrointestinal smooth muscle? Final 2014
- Submucous
- Myenteric
- Celiac
- Myenteric
A gastrointestinal smooth muscle showed 12 slow waves per minute. Which part of GIT does this muscle represent? 2014
- Small intestine
- Colon
- Stomach
- Small Intestines
Which of the following is a characteristic feature of smooth muscles in the gastrointestinal tract? 2013
- Depolarize by stretch
- Hyperpolarize by Ach
- Depolarize by norepinephrine
- Depolarize by stretch
Which of the following is a characteristic feature of smooth muscles in the gastrointestinal tract? 2013
Changing membrane potential
What is the correct sequence of contraction of smooth muscles? 2013
Ca-Calmodulin → MLCK → myosin-p → cross-bridges
Which of the following is present in the muscularis externa? 2011
Auerbach plexus
Decreased stomach Ph stimulates the secretion of which of the following? 2017, 2015
- Gastrin
- Secretin
- Somatostatin
- Histamine
- Somatostatin
Parietal cells secrete H+ ions in exchange of what? Final 2015
K+
After eating, the stomach pH increases even though acid secretion increases. What is the reason behind this? 2015
Buffering effect of food
Which of the following hormones acts as a paracrine to increase the gastric secretion? 2014, 2010
- Gastrin
- Histamine
- CCK
- Secretin
- Histamine
A hormone that inhibits both G cells and parietal cells? 2014
Somatostatin
After a meal, the active acid secretion by the parietal cells in the stomach results in changing the composition of blood leaving the stomach. What does that blood contain? 2014, 2011
- High levels of bicarbonate
- High levels of Potassium
- High levels of Chloride
- Low levels of Sodium
- High levels of bicarbonate
What enzyme is degraded in the alkaline medium? Final 2013, 2009
- Trypsin
- Chymase
- Pepsin
- Pancreatic lipase
- Trypsin
What stimulates secretion of secretin? 2013, 2008
Low duodenal pH
What describes the postprandial effect? Final 2012
Alkaline blood leaving the stomach after increased acid secretion