Physiology in Pregnancy Flashcards
What happens to Hg in pregnancy?
Decreases
What happens to WCC in pregnancy?
Increases
What happens to platelets in pregnancy?
Stays the same
What happens to CRP in pregnancy?
Stays the same
What happens to ESR in pregnancy?
Increases
What happens to urea in pregnancy?
Decreases
What happens to creatinine in pregnancy?
Decreases
What happens to urate in pregnancy?
Decreases but increases with gestation
What happens to D dimer in pregnancy?
Increases
What happens to bile acids in pregnancy?
Stays the same
What happens to Alkaline Phosphates in pregnancy?
Increase ++
What happens to liver enzymes (ALT/AST/GGT) in pregnancy?
Stay the same
What happens to albumin in pregnancy?
Decreases
What happens to total protein in pregnancy?
Decreases
What happens to 24hr protein in pregnancy?
Increases
Why does alkaline phosphate increase so much in pregnancy?
Placenta produces it
What is an increase in bile acid associated with in pregnancy?
Stillbirth (deliver at 37 wks)
In what circumstances would urea and creatinine increase during pregnancy?
Pre-eclampsia
What are the haematological changes that occur within pregnancy?
Hypercoaguable
Plasma volume increases
Decreased platelet count
2-3 fold increase in requirement for iron
10-20 fold increase in requirement for folate
WCC increase
RCC, Hg decrease
What changes occur to the renal system during pregnancy?
Dilatation off urinary collecting system Increased renal plasma flow GFR increases Protein excretion increased Glycosuria common Oedema Urea and creatinine decrease Microscopic haematuria may be present
In what circumstances will uric acid be higher in pregnancy?
Twin pregnancy
Overweight
What respiratory changes occur in pregnancy?
Significant increase in oxygen demand Increased respiratory rate Increased tidal volume Decreased functional residual capacity PCO2 decreases PEFR and FEV1 unchanged
What changes occur to breasts during pregnancy?
Increased size Increased vascularity Increased pigmentation of areola and nipple Secondary areola appears Montgomery tubercles appear on areola
What cardiovascular changes occur during pregnancy?
Increased circulating blood volume Systemic vascular resistance falls Increased blood flow Increased cardiac output Increased heart rate and stroke volume Increased O2 consumption
