Physiology final- digestive system Flashcards

1
Q

4 processes of the digestive system

A

motility, secretion, digestion and absorption

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2
Q

Muscularis Externa

A

major smooth muscle that lines digestive tract. circular inner layer and longitudinal outer layer.

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3
Q

digestive muscles

A

innervated by the vagus nerve and the parasympathetic nervous system.

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4
Q

Gastric Emptying

A

factors in the stomach: amount of chyme in stomach influences strength of contraction. Factors in Duodenum: fat, acid, hypertonicity, and distension (too much stuff in stomach)

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5
Q

Chief Cells

A

produce pepsinogen and when activated begin protein digestion

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6
Q

Parietal Cells

A

secrete HCl

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7
Q

Gastric mucosal Barrier

A

enables stomach to contain acid without injuring itself

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8
Q

Pancreatic secretion is regulated by

A

CCK (regulates gall bladder contraction) and secretin

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9
Q

Secretin

A

stimulates secretion of bicarbonate in response to low stomach pH/acidic levels.

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10
Q

CCK

A

Digests fat and protein. signals the gall bladder to contract. negative feedback loop for satiety, tells you to stop eating.

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11
Q

liver

A

largest and most metabolic organ in the body. makes and secretes bile salts

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12
Q

gall bladder

A

sits under the liver. release of bile comes from cck. common bile duct takes bile from the gall bladder to the lumen of the small intestine.

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13
Q

hepatic portal vein

A

takes drained blood from the digestive tract to the liver for processing and storage of absorbed nutrients. blood also then leaves the liver through the hepatic portal vein back to the heart. fat doesn’t go to the liver for absorption

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14
Q

Bile

A

made by hepatocytes, stored and concentrated in the gall bladder. made up of bile salts, cholesterol, lecithin and bilirubin

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15
Q

Bile salts

A

derivatives of cholesterol to break up fats into smaller molecules. function as detergents. 95% of bile salts are reabsorbed by the terminal ileum.

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16
Q

Liver functions not related to digestion

A

makes bile, detoxifying or degrading body wastes, synthesizes plasma proteins, stores glycogen, removes bacteria and worn out rbc’s

17
Q

brush-border enzymes

A

fixed on microvilli in the small intestine. activate enzymes that break down proteins and carbs. not secreted into the lumen.

18
Q

small intestine

A

almost all absorption occurs here. brush-border enzymes are here

19
Q

tripsinogen

A

made in the pancreas and is activated by brush-border enzymes to make active tripsin.

20
Q

digestion and absorption of carbs

A

carbs break down lactose, maltose and sucrose into monosaccharides. secondary active transport by sodium is used to move glucose from lumen into the capillary venous space.

21
Q

digestion and absorption of fats

A

bile salts coat fat droplets. pancreatic lipase breaks fats down into monoglycerides and fatty acids stored in micelles. monoglycerides and fatty acids then move out of micelles. monoglycerides and fatty acids move in through diffusion and cholesterol is transported into the cell. everything is added back together in the cell and make chylomicrons and moved to the lymphatic system to make lacteal.

22
Q

Gastrin (G cells)

A

stomach cells, stimulate parietal cells

23
Q

zymogens

A

inactive, secreted by the pancreas into the lumen of the small intestine to be activated. includes tripsinogen.