Physiology Extra Flashcards

1
Q

how much oxygen per dissolved blood at 100mmhg

A

3ml/l

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2
Q

whats in LARGE synaptic vesicles

A

neuropeptides

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3
Q

what happens to alveolar ventilation as RR increases

A

decreases

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4
Q

what does anatomical dead space equal in a healthy person

A

physiological dead space

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5
Q

how does noradrenaline increase HR

A

increase calcium and depolarising membrane in stage 4

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6
Q

what has the greatest effect on bloods ability to transport o2

A

Hb

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7
Q

normal gfr

A

125ml.min

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8
Q

activates pepsin

A

HCL

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9
Q

terminates pepsin

A

pancreatic juice

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10
Q

adrenergic receptors that increase AV node

A

B1 B2

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11
Q

What does HDL to

A

takes cholesterol to liver

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12
Q

what does a deficiency of B oxidation fatty acids cause

A

cardiomyopathy

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13
Q

what initially happens to o2 curve at altitude

A

goes left as increase RR

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14
Q

dig and K

A

high makes tox worse, low increases chance of tox

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15
Q

what do CD4 cells lack

A

Fc

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16
Q

what does ACH do to renal flow

A

increases

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17
Q

what do medullary chemoreceptors monitor

A

H and indirectly co2

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18
Q

Glomerular pressure compared to systemic

A

40%

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19
Q

what do carotid and aortic bodies respond to

A

ph, co2 and o2

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20
Q

o2 needed at depth
v/q mismatch

A

less
exaggerated

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21
Q

how do thyroid hormones work

A

same as steroid

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22
Q

M and H gate

A
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23
Q

where in tubule is interstitial and intratublar osmolality the same

A

descending limb

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24
Q

why does LV work harder

A

greater afterload

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25
where do prostaglandins mainly act
where they are produced
26
role of surfactant
reduce surface tension and stop pulmonary oedema
27
particles less than 0.1 microns
absorbed by alveoli
28
respiration control in exercise sleep
above medulla medulla
29
what is saltatory conduction decreased NA
myelin decreases impulse
30
what increases smooth muscle contraction
ACh and phospho p opposite to skeletal
31
mass action
desaturated HB carring co2
32
what can happen to the curve in stored blood/
shift left
33
antibodies to what with repeated transfusions
m n kel duffy
34
greatest wall thickness to lumen ratio temp
arterioles AV anastamoses
35
where does blood go during fainting
skeletal muscle
36
highest o2 consumption at rest
heart
37
what clots milk
rennin
38
what is linked to heriditary angioedema
kinins
39
where does NA/K/CL exchange occur togther N/H N/CL
thick ascending limb via co-transporter thick ascending limb via exchanger DCT co transporter
40
Troponin T I C
binds T to **T**ropomysin **I**nhibits binding site for **C**alcium
41
significant ST change in chest leads
0.5mm
42
hypokalaemia ecg
long PR st depression flattened T U Long QT **QRS WIDE HYPER**
43
where does true acethylcholine esterase function
nerve endings
44
what goes up after partial hepatectomy
oestrogen
45
what fat has SNS
brown
46
co2 excretion at exercise
8l/min
47
what is needed for alveolar gas equation
fi02
48
sodium in renal disease
increased resorption
49
what gas to CAI cause
hypokalaemic metabolic acidosis
50
where is pepsin formed
stomach
51
cardiac axis
52
normal Na reabsorbed over 24 hours
99%
53
what does a high V/Q ratio cause
anatomical dead space
54
how is co2 carried
60% bicarb via carbonic anhydrase and carbonic acid 10% dissolved
55
how much sodium is reabsorped in collecting duct
3%
56
how much more soluble in blood is co2 over o2
20
57
equation for compliance
C =V/P use litres
58
summary kidney ion transport
aldosterone causes H secretion via h/atpase pump h/K exchanger in collecting duct k/na/cl co transporter in PCT or na/h exchange
59
how does norad cause coronary vessel dilatation
secondary mediators via b adrenergic
60
how does urinary sodium compare to plasma usually?
lower
61
how many ach vesicles released per time
60
62
small dense vesicles
catecholamines
63
when is a third heart sound normal
young healthy people
64
what to PG do to renal blood flow
increase cortex decrease medulla
65
carbonic anhydrase equation
66
what does ANP do to capillaries
leaky
67
how is ATP used in muscle contraction
contraction and relaxation
68
what removes ACH outside of synapose
non specific ACHesterase
69
gastric PH when fasting?
1
70
what do thyroid hormones to do circuation
reduce peripheral vascular resistance same as valsalva
71
how may you measure physiolical dead space
bohr
72
when is lung best ventilated
on its side
73
why does more air go to alveoli at base? where is V/Q the lowest
more compliant base
74
what can conrol pancretic secretion
ACH
75
principal buffer in interstitial fluid
carbnic acid
76
main buffers
blood - protein intracellular - phosphate interstitum - carbonic acid