Pathology extra Flashcards

1
Q

hepatitis is what type of virus

A

hepadnaviradae

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2
Q

where does cytostolic Ca come from

A

Mitochondria

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3
Q

common cancer in males and females

A

lung

doubled in last 40 years

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4
Q

most common site of MI

when does irreversible cell injury occur

A

LAD

20-40 mins

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5
Q

most prominent risk reduction for stopping smoking

A

MI

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6
Q

transfusion reaction hypersensitivity

serum sickness/arthus

tuburculin

A

2

3

4

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7
Q

what dont familial tumours have

A

specific phenotypes

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8
Q

what collagen is deposited in cirrhosis

A

1.3

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9
Q

most common cause AVN

A

steroids

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10
Q

is metaplasia reversible

A

yes

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11
Q

benign bone tumour

A

osteochondroma

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12
Q

percentage with islet cell antibodies in t1dm

A

70-80

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13
Q

oestrogen and osteoclasts

A

inhibits them

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14
Q

RSV and x-ray

A

interstitial infiltrates

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15
Q

in hopsital death rate MI

A

7%

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16
Q

hypersensitivity involving lymphocytes

A

3

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17
Q

what is the major cause of tissue damage in tb

A

granulomas

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18
Q

what channel causes insulin release

A

VGCC

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19
Q

perecentage of MI causing arrthymia

A

90

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20
Q

most common cause pericarditis

A

viral

post mi

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21
Q

bigger effect on tissues - T3 or T4?

A

T3

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22
Q

compound commonly lost in OA

A

hyaluronan

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23
Q

how long does EPO take to work

what stops it

A

5-7 days

theophylline

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24
Q

how long are stored platelets viable for

A

24 hours

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25
characteristics of aids
cd4 loss greater less hypersensitivity increased circulating immune complexes
26
what defines hep b carrier state
HBsAg for over 6 months
27
what are the majority of HIV cases from
heterosexual
28
what inactivates free radicals
glutathione
29
how does rhabo damage muscles
damages sarcomere
30
what size are most infarcts biggest risk for infarcts
wedge bed
31
ATP loss in infarction
depletion in seconds 50% normal 10 mins 10% normal 40 mins
32
when do fatty streaks appear in the aorta
1yr old
33
what causes conjunctivitis
adenovirus
34
anatomy of blood vessel
35
what does SCA anaemia do to bone marrow
normoplastic hyperplasia
36
lines of zahn no RBC in supernatant
antimortem post
37
key in melanoma
nodule development
38
key transporter in insulin
GLUT2
39
contraction bands in MI
reperfusion injury
40
common presentation of appendicits in preschool
gastro NB neutrophil invasion of muscular layer
41
what percentage of endocarditis culture nothing
10%
42
why does metaplasia occur
reprogramming of cells
43
most common site of malignancy haem spread
liver and lung
44
what happens to haptoglobins in haemolysis
go up
45
what does tetanus produce perfringens
heavy and light chain alpha
46
where is serotonin pre formed
mast cells and platelets
47
where is Iga found
resp GI
48
mitotic signal protein
RAS
49
highest risk in male smokers
lip, oral
50
what causes croup
parainfluenze
51
endothelium v epithelium
endo enclosed epi outside world
52
what forms bradykini
kallikrellin
53
what GI cancer does smoking cause
pancreatic also saccular aneurysms
54
hepatitis A incubation
2-6 weeks
55
what stimulates IL1 in osteroporosis
low oestrogen
56
H in getsmashed
hypercalcaemia hypertriglycerides
57
Acyanotic heart disease
VSD
58
sign of irreversible cell injury
swelling and fatty change
59
how does botulism work
inhibits ACH
60
where do lymphocytes usually live
lymph nodes spleen thymus
61
segmental glomerulosclerosis
loss of foot processes
62
vegetarian stones
calcium oxalate
63
what is phimosis linked to?
carcinomas