physiology Flashcards
cardiac impulse
electrical signals which control the heart are generated within the heart itself
autorhythmic
heart is capable of beating rhythmically in the absence of external stimuli
SA node
sino atrial
in the upper right atrium close to where the superior vena cava enters
normally drives the entire heart
controlled by the SA is in sinus rhythm
AV node
atrio ventricular
small bundle of specialised cardiac cells
junction of the atria and ventricles
conduction is delayed in the AV node allowing atrial systole to precede ventricular systole
bundle of his and Purkinje fibres
allow rapid spread of action potential to the ventricles
SA to AV node
communication via gap junctions some internodal pathways
impulse in muscle cell
Na influx
decrease Na, increase Ca
decrease Ca, increase K
K efflux
actin
thin filament
causes the lighter appearance in myofibrils and fibres
myosin
thick filament
causes the darker appearance
refractory period
period following an action potential in which it is not possible to produce another action potential
stroke volume
end diastolic - end systolic
regulated by intrinsic and extrinsic mechanisms
end diastolic volume determines the cardiac preload
end diastolic volume is determined by venous return to the heart
Frank-Starling curve
relationship between venous return, end diastolic volume and stroke volume
afterload
the resistance into which the heart is pumping
extra load is imposed after the heart has contracted
cardiac output
stroke volume x heart rate
cardiac cycle
passive filling atrial contraction isovolumetric ventricular contraction ventricular ejection isovolumetric ventricular relaxation
passive filling
pressure in atria and ventricle are almost zero
AV valves open so venous returns flow into ventricles
aortic valve is closed
ventricles 80% full by passive filling
atrial contraction
P wave signal atrial depolarisation
atria contract between P wave and QRS
complete the end diastolic volume
isovolumetric ventricular contraction
after QRS
ventricular pressure rises
when ventricular pressure exceeds atrial pressure the AV valve closes LUB
ventricular pressure rises steeply as aortic valve is still closed