peripheral vascular disease Flashcards
aneurysm
dilation of a vessel by more than 50% of its normal diameter
true aneurysm
vessel wall is intact
false aneurysm
breach in vessel wall
mycotic aneurysm
arises secondary to an infectious process
AAA presentation
75% are asymptomatic, identified on imaging
symptomatic - pain, thrashing, rupture
AAA rupture
sudden onset apigastric/central pain a radiate through to back may mimic renal colic collapse examination - hypo/hypertensive, pulsatile expansive mass, tender, transmitted pulse, peripheral pulses, tachycardia
AAA imaging
duple ultrasound
CT
AAA management
open repair - laparotomy, clamp aorta and iliacs, Dacron graft, tube vs bifurcated graft
endovascular aneurysm repair EVAR - exclude AAA from inside the vessel, inserted via peripheral artery, x-ray guided, modular component
plaque formation
activated platelets
LDL cholesterol
inflammatory response
intermittent claudication
when insufficient blood reaches exercising muscles
pain free at rest
after variable periods of exercise ischaemic pain in affected limb
relieved by further rest
ABPI
ankle brachal pressur index
normal 0.9-1.2
claudication 0.4-0.85
severe <0.4
intermittent claudication investigations
non invasive - ABPI, duplex ultrasound scanning
invasive - magnetic resonance angiography, CT, catheter angiography
intermittent claudication treatment
slow progress - smoking, lipid lowering, antiplatelet, hypertension Rx, diabetes Rx,
information/realistic expectation
exercise training and drugs - 30 min 3 times a week, cilostozol, pentoxifylline, naftidrofuryl
angioplasty +/- stent
surgery - inflow and outflow bypass
critical limb ischaemia
rest pain - toe/foot ischaemia
ulcers/gangrene - severe ischaemia and damage
requires strong analgesia
worse at night
helped by sitting and putting the leg in a dependent position and getting up and walking about
results inn lower limb amputation
critical limb ischaemia clinical exam
cool to touch, no peripheral pulses, colour change, poor tissue nutrition, venous guttering, ulcers, gangrene