physiology Flashcards

1
Q

what is the function of skeletal muscles

A
maintain posture
respiration
heat production (shivering)
metabolism
movement
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2
Q

what are the 3 types of muscle

A

cardiac
skeletal
smooth

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3
Q

describe cardiac muscle

A

striated and involuntary

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4
Q

describe smooth muscle

A

non-striated and involuntary

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5
Q

describe skeletal muscle

A

striated and voluntary

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6
Q

what innervates cardiac muscles

A

ANS

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7
Q

what innervates smooth muscles

A

ANS

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8
Q

what innervates skeletal muscle

A

somatic nervous system,

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9
Q

what is the transmitter at the skeletal muscle neuromuscular junction

A

acetylcholine

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10
Q

what initiates skeletal muscle

A

neurogenic mechanism

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11
Q

what initiates cardiac muscle

A

myogenic (pacemaker potenital)

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12
Q

what is a motor neurone

A

a single alpha motor neurone and all the skeletal muscle fibres that it innervates

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13
Q

what does the number of muscle fibres per motor unit depend on

A

the function served by the muscle. if precision is more important than power then there will be fewer fibres and vice versa

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14
Q

how are skeletal muscles organised

A

whole muscle to muscle fibre to myofibrils to sarcomere which are made up of myosin and actin

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15
Q

what is a myofibril

A

a specialised intracellular structure

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16
Q

what is a functional unit

A

the smallest component capable of performing the functions of the organ

17
Q

where is a sarcomere located

A

between two z-lines

18
Q

what is a z-line

A

connects the thin filaments of two adjoining sarcomeres

19
Q

what are the 4 zones of a sarcomere

A

A-band
H-zone
M-line
I-band

20
Q

what is a A-band

A

thick filaments with portions of thin that overlap both ends of the thick

21
Q

what is the H-zone

A

lighter areas within the middle of the A-band where the thin filaments don’t reach

22
Q

what is the M-line

A

extends vertically down the middle of the A-band, within the centre of the H-zone

23
Q

what is the I-band

A

consists of the remains portion of thin filaments that don’t project onto the A-band

24
Q

how is muscle tension produced

A

the sliding of actin on myosin

25
Q

what is ATP needed for in muscle contraction

A

contraction
relaxation
to release cross bridges
pump Ca2+ back into the SR

26
Q

what is Ca2+ needed for in muscle contraction

A

switch on cross-bridge formation

27
Q

what is excitation contraction coupling

A

the process where the surface AP results in activation coupling of the contractile structures of muscle fibres

28
Q

explain muscle contraction

A

acetylcholine is released by the motor neurone
the surface AP spreads down the transverse T-tubles
this triggers the release of Ca2+ from the SR
Ca2+ binds to troponin which pulls the troponin-tropomysoin complex aside to expose the bind site
cross-bridge formation occurs