physiology Flashcards
What is a bipotential tissue
Tissue that hasnt differentiate
What protein direct development as a male
SRY
With sry protein, gonadal medulla develops into…
Testis
In absence of SRY protein, gonadal cortex becoes…
Ovarian tissue
View sexual differentiation table
View
2 type of cells in testis
Leydig cells
Sertoli cells
In women , Mullerian duct develops into … and wolffian duct …
Vagina
Uterus
Fallopian tubes
…degenerate
What is the pathway for male genitalia development
Presence of SRY gene => produces the SRY proteins
production of proteins SRY => gonad medulla differentiate into testis
testis has leydig cells and Sertoli cells
Leydig cells secrete testosterone => causes development of wolffian duct into vas deferens, epididymis and seminal vesicles
DHT control development of external genitalia
Sertoli cells secrete antimullarian hormone which causes regression of mullerian duct
Pathway for female genitalia development
No SRY gene so no proteins
Gonadal cortex diff differentiate into ovarian tissue
Gonadal medulla degenerate
Mullerian duct become vagina uterus fallopian tubes
wolffian duct degenerates
What are the sex steroid hormones Produced by the ovary
Estrogen
progesterone
What are the sex steroids produced by the testis
dihydrotestosterone
Testosterone
Do adrenal glands produce small amounts of sex steroids
Yes they do
What is the precursor of all sex steroids
Cholesterol
What’s enzyme convert testosterone to estradiol
Aromatase
What enzyme converts testosterone to dihydrotestosterone
5 reductase
In reproduction what hormone is produced by the hypothalamus
Gonadotropin releasing hormone GnRH
In reproduction what hormones are produced by the anterior pituitary
luteinizing hormone LH
follicle-stimulating hormone FSH
Pathway of hormonal control of reproduction
Stimuli comes to central nervous system
hypothalamus releases gonadotropin releasing hormone
gonadotropin releasing hormone causes release of Luiteinizing Hormone and follicle stimulating hormone from the anterior pituitary
Luiteinizing Hormone causes release of steroids and peptides from endocrine cells in the gonads
follicle-stimulating hormone Induce gamete production from the gonads
What is the effect if you have low androgen or estrogen
Absence or negative feedback with increased gonadotrophin level
Moderates estrogen or androgen effects
negative feedback with decreased gonadotropin level
High androgen level effect feedback
Negative feedback with decreased gonadotropin level
Sustain high estrogen affect on feedback
Positive feedback with increased Gonadotropin level
What are the external genitalia of males
Scrotum
penis
What is the common passageway in male genitalia
Urethra
What are the accessory glands and ducts of the male reproductive system
Prostate gland
seminal vesicle
bulbourethral gland
What organ produces sperm
Testes through seminiferous tubules
Where do sperm mature in the testis
Epididymis
What is the passage way of sperm from the testes to the abdomen to get into the urethra
Vas deferens
What is the function of the Sertoli cells
Support and surrounds developing sperm
How do you LH & SSH act on leydig and Sertoli cells
LH act on Leydig cells to produce testosterone
FSH act on Sertoli cells to produce cell products like paracrine signals needed for sperm development , androgen binding protein and inhibin
Accessory glands - Seminal vesicles ,prostate gland , Bulbourethral gland
What are all the function of the seminal vesicles
Sperm volume
fructose
vitamin C
prostaglandins
What are all the function of the prostate gland
Sperm volume
buffers
citric acid
enzymes
What are the function of the bulbourethral gland
Mucus
buffers
sperm volume
What is the composition of semen
Sperm mucus water Buffers nutrients( fructose citric acid vitamin C carnitine ) enzymes zinc prostaglandins
What are the secondary sexual characteristics of male
General body shape muscle development body hair deep voice beard male sexual behavior like libido
What are the general function of estrogen and progesterone
Prepare the uterus for possible pregnancy
What are the J external genitalia of female
Labia majora labia minora clitoris vagina with hymen urethral opening in labia minora
What are the internal organs of the female reproductive system
Vagina
uterus- cervix ,endometrium ,myometrium
fallopian tube with fimbriae
ovary
What are the follicle in the ovary
The structure where oocytes develop