Physiology Flashcards

1
Q

what are the three layers of the retina from inner to outer?

A

ganglion cells
bipolar cells
photoreceptors

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2
Q

what two lateral connections influence signal processing in the retina?

A

horizontal cells

amacrine cells

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3
Q

what does the photoreceptor cell do?

A

converts light to neural signals

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4
Q

what are the four main regions of the photoreceptor?

A

outer segment
inner segment
cell body
synaptic terminal

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5
Q

which part of the photoreceptor cell contains the receptors?

A

outer segment

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6
Q

which part of the photoreceptor synapses with the bipolar cells?

A

synaptic terminal cells

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7
Q

what are the two types of photoreceptors?

A

rods

cones

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8
Q

what is the membrane potential of a photoreceptor in the dark and why?

A

depolarised (+)

sodium channel is open in the dark

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9
Q

what is the membrane potential of a photoreceptor in the light and why?

A

hyperpolarised (-)

sodium channel is closed

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10
Q

what are visual pigment molecules called?

A

rhodopsin

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11
Q

what is rhodopsin made of?

A

11-cis-retinal and opsin

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12
Q

what effect does light have on rhodopsin?

A

converts 11-cis-retinal to its active form, all trans retinal

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13
Q

what determines visual acuity?

A
photoreceptor spacing (closer the better)
refractive power
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14
Q

what light do rods see?

A

dim light

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15
Q

describe the convergence of rods

A

high - multiple rods to one ganglion

increased sensitivity to light, decreased visual acuity

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16
Q

where are rods found?

A

equally around the retina

not the fovea

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17
Q

what light do cones see?

A

normal daylight

18
Q

describe the convergence of cones

A

low - few cones to one ganglion

decreased sensitivity to light, increased visual acuity

19
Q

where are cones found?

A

concentrated to the fovea

20
Q

how can cones provide colour vision?

A

they contain different opsins that respond to light of specific wavelengths

21
Q

what three colours can cones see?

A

red
blue
green

22
Q

what is the visual field of one eye called?

A

the monocular visual field

23
Q

what is the visual field of both eyes called?

A

the binocular visual field

24
Q

what divides the retina in half?

A

the fovea

25
Q

what are the two halves of the retina?

A

nasal

temporal

26
Q

what happens to the fibres from the nasal retina at the optic chiasma?

A

cross over to form the optic tracts

27
Q

what is contained in an optic tract?

A

the nasal and temporal fibres from one eye

28
Q

where does the optic tract pass to?

A

the lateral geniculate nucleus

then the primary visual cortex

29
Q

what is aqueous humour?

A

a specialised fluid that bathes the structures within the eye

30
Q

what does aqueous humour do?

A

provides oxygen

contains bicarbonate which buffers hydrogen ions

31
Q

where is aqueous humour produced?

A

the epithelial layer of the ciliary body

32
Q

where is aqueous humour secreted into?

A

the posterior chamber of the eye

33
Q

where does aqueous humour flow?

A

into the anterior chamber

34
Q

where does aqueous humour drain?

A

scleral venous sinus

canal of Schlemm

35
Q

where is the canal of Schlemm found?

A

the iridocorneal angle

36
Q

what are the two layers of the ciliary epithelium?

A

PE

NPE

37
Q

what is PE?

A

a forward continuatio of the pigment epithelium of the retina

38
Q

what is NPE?

A

non pigmented epithelium

39
Q

what does the basolateral side of the PE face?

A

the blood

40
Q

what causes raised intra ocular pressure in glaucoma?

A

imbalance in rate of production and drainage of aqeuous humour

41
Q

what drugs can be used to reduce pressure in glaucoma?

A

carbonic anhydrase inhibitors

42
Q

name two carbonic anhydrase inhibitors

A

dorzolamide

acetazolamide