Immunology Flashcards
how do tears provide protection to the eye?
physical barrier
wipes away things that shouldn’t be there
the mucous layer is anti adhesive
name three anti microbial chemicals in tears
lysozyme
lactoferrin
IgA
name three immune cells found in tears
neutrophils
macrophages
conjunctival mast cells
what is the main antigen presenting cell of the external eye?
langerhans cells
where are langerhans cells most abundant in the external eye?
the limbus
less in the peripheral cornea
where are langerhans cells absent in the external eye?
the central third of the cornea
what is the only part of the eye with lymphatic drainage?
the conjunctiva
what is immune privilege?
the ability to tolerate introduction of antigens without eliciting an inflammatory immune response
name three body parts that have immune privilege
testes
placenta
eyes
name a type I hypersensitivity reaction affecting the eye
acute allergic conjunctivitis
name a type II hypersensitivity reaction affecting the eye
ocular cicatricial pemphigoid
what is ocular cicatricial pemphigoid?
a type of autoimmune conjunctivitis causing blistering and scarring of the conjunctiva
name a type III hypersensitivity reaction affecting the eye
autoimmune corneal melting
name a type IV hypersensitivity reaction affecting the eye
corneal graft rejection
