Physiological Psychology and Pharmacology Flashcards
Recent studies suggest that, for patients who develop tardive dyskinesia (uncontrollable facial or body movements) as a result of long-term neuroleptic use symptoms
May eventually improve to some degree following neuroleptic withdrawal
Following a head injury, an adult exhibits a period of post-traumatic amnesia that lasts for nearly one hour. Two days later, he is still experiencing a number of symptoms including headache, fatigue, irritability, visual disturbances, and impair attention. What can he expect in terms of recovery?
Most or all of the neurological functions and resolution of most or all symptoms within 3-6 months.
Which of the following describes the most likely outcome for a one-year old child who sustains left hemisphere brain injury that involves extensive damage to Broca’s area?
The child will eventually exhibit language abilities in the low-normal to normal range due to takeover of language functions by the right hemisphere.
An MRI of a patient with Huntington’s disease is most likely to show atrophy in which brain structure?
Caudate Nucleus
In comparison to conventional neuroleptics, risperidone (risperdal) is ____ likely to produce tardive dyskinesia
Less
Practical Clinical Trials
Designed to evaluate the effects of interventions delivered under typical community conditions
What is the correct sequence of events that occur during action potential?
Sodium enters the cell and the cell depolarizes. Then potassium leaves the cell and the cell repolarizes.
When working with a “split-brain” patient, you would notice that they have the most difficulty with what?
Sensory functions
What are the symptoms of a common migraine?
Does not begin with aura and may be exacerbated by bending over or lifting
Kandel and Schwartz (1982) studied habituation to Aplysia, an invertebrate marine animal, in order to obtain information on
Neuronal processes underlying memory
L-dopa acts as a
Dopamine agonist (activate dopamine receptors)
Following a head injury, a middle-aged man experiences a loss of sensation in the fingers of his left hand. Most likely the damage involves the
Postcentral gyrus
Drugs that block the activity of _____ produce dry mouth, blurred vision, postural hypotension, tachycardia, and sedation.
ACh
What medications are useful for alleviating psychotic symptoms associated with schizophrenia and psychotic disorder?
Risperidone (Risperdal), olanzapine (Zyprexa), chlorpromazine (Thorazine)
The complete loss of color vision resulting from lack of functioning cone cells is referred to as:
Achromatopsia
Anomia (difficulty recalling the names of everyday objects) is a likely outcome of damage to which area of the brain?
Wernicke’s area (manages speech)
A tumor in the medial hypothalamus is most likely to produce what?
Outbursts of aggressive behavior
To reduced symptoms of tardive dyskinesia, what would be the most effective treatment?
A drug that decreases dopamine levels
Where is the Wernicke’s area located in the brain?
Temporal Lobe
For most patients with Parkinson’s Disease, depression
Appears to be endogenous to the disorder and may precede motor symptoms, especially in younger patients
Agnosia
Inability to recognize familiar objects or sounds
Akathisia
Inability to sit or stand still; uncomfortable sense of restlessness
Akinesia
Complete or almost complete loss of movement
Anosognosia
Failure to recognize one’s own neurological symptoms
Aphasia
Disturbance in previously acquired language skills
Apraxia
Inability to carry out purposeful movements despite normal muscle power and control
Asomatognosia
Inability to recognize parts of one’s own body
Ataxia
Incoordination, clumsiness, lack of balance
Athetosis
Slow writhing involuntary movements
Bradykinesia
Slowness of movement
Chorea
Irregular, involuntary, rapid jerky movements, usually in the face, limbs, and trunk
Dyskinesia
Abnormal muscle movement including twitchy, jerky, and writhing movements (chorea, tics, tremors)
Dysprosody
Disturbance in the stress, pitch, and rhythm of speech
Parkinsonism
Masklike face, hand tremor, increasing rigidity, slowed voluntary movement
Paresthesia
Altered sensation in the skin that causes numbness or tingling
Prosopagnosia
Inability to recognize familiar faces
Tardive Dyskinesia
Repetitive oral and facial grimaces, tongue movements, spasms of the neck and head, jerky movements of the limbs and trunk
Computed Tomography
CT utilizes X-rays to obtain images of horizontal slices of the brain and is used to diagnose tumors, blood clots, multiple sclerosis, and other conditions.
Magnetic Resonance Imaging
MRI uses magnetic fields and radio waves to produce cross-sectional images of the brain. It provides clearer images than a CT scan.
Positron-Emission Tomography (PET)
When using PET, the individual is injected with a radioactive tracer that is taken up by active brain cells. PET scans provide information on regional cerebral blood flow, glucose metabolism, and oxygen consumption, which are presumed to correlate with level of neural activity.
Single Proton Emission Computed Tomography (SPECT)
SPECT is similar to PET but is easier and less expensive to use but produces less detailed images.
Functional MRI (fMRI)
Functional MRI is similar to MRI but provides information on the brain’s metabolic activity.©2020, AATBS
Somatic Nervous System (SNS)
The SNS contains sensory and motor neurons that link the Central Nervous System to the skeletal muscles.
Autonomic Nervous System (ANS)
The ANS consists of sensory and motor neurons that connect the Central Nervous System muscles of the internal organs and glands.
What is the sympathetic branch of the automatic nervous system?
The sympathetic branch mediates the fight-or-flight response and energy output.
What is the parasympathetic branch of the automatic nervous system?
The parasympathetic branch regulates “housekeeping” functions, relaxation and recuperation, and energy conservation.
Medulla
Located in the hindbrain. The medulla controls important reflexes (e.g., coughing and swallowing) and regulates breathing, heart rate, blood pressure, and other vital functions.
Cerebellum
Located in the hindbrain. The cerebellum is involved in posture and balance, coordinates voluntary movements, and plays a role in motor learning (e.g., riding a bicycle). Damage can cause ataxia (loss of balance, slurred speech, tremors).
Midbrain
The midbrain includes the reticular formation, which is involved in sleep and wakefulness, motor movements, pain perception, and some reflexes. It contains the ascending reticular activating system (ARAS), which is responsible for awareness, arousal, and attention.
Hypothalamus
Located in the forebrain. The hypothalamus is involved in hunger and thirst, sex, sleep, body temperature, movement, and emotional reactions (e.g., physiological reactions associated with fear and rage). It regulates the body’s homeostasis (e.g., temperature, fluid and electrolyte balance, weight) through its influence on the ANS and endocrine glands.
Suprachiasmatic Nucleus
Located in the hypothalamus. It controls circadian and seasonal cycles (e.g., immune response, reproductive activity)
Mammillary Bodies
Located in the hypothalamus. They play a role in memory.
Thalamus
Located in the forebrain. The thalamus is the “relay station” for all senses except olfaction. It’s also involved in memory (e.g., damage can produce Korsakoff syndrome, which involves anterograde amnesia, retrograde amnesia, and confabulation).
Basal Ganglia
Located in the forebrain. The basal ganglia include the caudate nucleus, putamen, and globus pallidus. These structures are important in organizing and coordinating voluntary movements. Abnormalities have been linked to Huntington’s disease, Parkinson’s disease, Tourette’s disorder, OCD, schizophrenia, and ADHD.
Limbic System
Located in the forebrain. The limbic system is involved in the regulation of motivation and emotions and plays a role in some cognitive abilities.
Amygdala
Part of the limbic system. The amygdala controls emotional reactivity and attaches emotion to memory. Bilateral lesions in the amygdala and temporal lobes in primates produce Kluver-Bucy syndrome (reduced fear and aggression, increased docility, compulsive oral behaviors, altered dietary habits, hypersexuality, psychic blindness). Abnormalities have been linked to anxiety disorders and depression.
Hippocampus
Part of the limbic system. The hippocampus is involved in processing spatial, visual, and verbal memories and consolidating declarative memories.A smaller-than-normal hippocampus has been found in some individuals with PTSD and depression.
Frontal Lobe
The frontal lobe contains (1) theprimary motor cortex; (2) the prefrontal cortex (which is involved in emotions, self-awareness, and executive functioning); and (3) Broca’s area. Damage may cause loss of reflexes and muscle tone and other motor impairments; deficits in higher-order cognitive functions; personality and emotional changes (e.g., pseudodepression or pseudopsychopathy); and Broca’s (expressive) aphasia.
Parietal Lobe
The parietal lobe contains the somatosensory cortex which mediates pressure, temperature, pain, taste, and proprioception. Damage may cause contralateral neglect; apraxia; tactile agnosia; asomatognosia; anosognosia; and Gerstmann’s syndrome.
Temporal Lobe
The temporal lobe contains the auditory cortex (which is involved in auditory sensation and perception) and Wernicke’s area. Damage may result in disturbances in auditory sensation and perception (e.g., auditory agnosia, auditory hallucinations); impaired declarative memory; and Wernicke’s (receptive) aphasia.
Occipital Lobe
The occipital lobe contains the visual cortex which is responsible for visual sensation and perception. Damage can cause disturbances in visual sensation and perception (e.g., prosopagnosia, visual agnosia, color agnosia, cortical blindness).
Left (Dominant) Hemisphere
The left hemisphere controls written and spoken language; verbal memory; logical, rational thought; and positive emotions.
Right (Nondominant) Hemisphere
The right hemisphere is responsible for visual-spatial skills; creative, intuitive thought; nonverbal memory; and negative emotions.